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Dermatology
Dermatology
Dermatology
Dermatology
Dermatology
The medical specialty that studies the anatomy and
physiology of the integumentary system and uses
diagnostic tests, medical and surgical procedures, and
drugs to treat integumentary diseases.
Figure 7-1 Integumentary system
Anatomy and Physiology
• The integumentary system consists of the skin
(epidermis and dermis), sebaceous glands, hair, and
nails.
• Protects the body and is the first line of defense
against invading microorganisms
• Includes the sense of touch
Anatomy of the Integumentary
System
• Skin consists of two different layers:
The epidermis is categorized as epithelial tissue and
covers the external surface of the body.
The epidermis also includes the mucous membranes
that line the walls of internal cavities that connect to the
outside of the body.
The dermis is categorized as connective tissue.
Anatomy of the Integumentary
System (con't)
• Epidermis
This is the thin, outermost layer of the skin.
It contains cells that have no nuclei and are filled with
keratin, a hard, fibrous protein.
These cells form a protective layer, but they are dead
cells, so they are constantly being shed or sloughed off
in the process known as exfoliation.
Anatomy of the Integumentary
System (con't)
• Epidermis (con't)
The deepest part (basal layer) of the epidermis is
composed of living cells that are constantly dividing and
being forced to the surface (exfoliation).
Does not contain any blood vessels; it receives nutrients
and oxygen from the blood vessels in the dermis
Anatomy of the Integumentary
System (con't)
• Epidermis (con't)
Contains melanocytes, pigment cells that produce
melanin, a dark brown or black pigment that absorbs
ultraviolet light from the sun to protect the DNA in skin
cells from undergoing genetic mutations
Figure 7-2 Epidermis and dermis
Anatomy of the Integumentary
System (con't)
• Dermis
A thicker layer beneath the epidermis
Contains collagen fibers (firm, white protein) and
elastin fibers (elastic, yellow protein)
Contains arteries, veins, and neurons (nerve cells), as
well as hair follicles, sebaceous glands, and sweat glands
A dermatome is a specific area on the skin that sends
sensory information to the spinal cord.
Anatomy of the Integumentary
System (con't)
• Sebaceous and Sweat Glands
Sebaceous glands are a type of exocrine gland in the
dermis that secrete sebum through a duct into a hair
follicle.
Also known as oil glands.
Sweat glands are also exocrine glands.
Sweat contains water, sodium, and small amounts of
body waste (urea, ammonia, creatinine).
Anatomy of the Integumentary
System (con't)
• Sebaceous and Sweat Glands (con't)
Sweat glands help to regulate the body temperature.
The process of sweating and the sweat itself are both
known as perspiration.
The sweat glands are also known as the sudoriferous
glands.
Anatomy of the Integumentary
System (con't)
• Hair
Covers most of the body
Additional facial, axillary, and pubic hairs appear during
puberty.
Forms in a hair follicle in the dermis
Anatomy of the Integumentary
System (con't)
• Hair (con't)
Melanocytes give color to the hair.
Hair cells are filled with keratin, which makes the hair
shaft strong.
Usually, the hair lies flat on the surface of the skin, but
when the skin is cold, a tiny erector muscle at the base of
the hair follicle contracts and causes the hair to stand up
(piloerection).
Xie Qiuping Tran Van Hay
Hair Length = 18’ 5.54” Hair Length = 20’ 3.6”
Anatomy of the Integumentary
System (con't)
• Nails
Cover and protect the distal ends of the fingers and toes
Each nail consists of a nail plate, nail bed, cuticle,
lunula, and nail root.
Figure 7-4 Nail
Anatomy of the Integumentary
System (con't)
• Subcutaneous Tissue
A loose, connective tissue directly beneath the dermis of
the skin
Composed of adipose tissue or fat that contains
lipocytes (fat-storing cells)
Provides a layer of insulation to conserve internal body
heat
Anatomy of the Integumentary
System (con't)
• Subcutaneous Tissue (con't)
Can be thin or as thick as several inches
Subcutaneous layer also acts as a cushion to protect the
bones and internal organs
Physiology of an Allergic
Reaction
An allergy or allergic reaction is a hypersensitivity
response to certain types of antigens known as
allergens.
Allergens include cells from plant and animal sources
(foods, pollens, molds, animal dander), as well as dust,
chemicals, and drugs.
Physiology of an Allergic
Reaction (con't)
The basis of all allergic reactions is the release of
histamine from basophils in the blood and mast cells
in the connective tissue.
A local reaction occurs when an allergen touches the
skin or mucous membranes of a hypersensitive
individual
Anaphylaxis is a severe systemic allergic reaction that
can be life-treatening
Epi-pen
Figure 7-5 Edema
Figure 7-6 Types of skin lesions.
Figure 7-7 Necrosis and pallo
Meyer/Custom Medical Stock Photo, Inc.
Figure 7-9 Second-degree burn of the hand
Logical Images, Inc.
Figure 7-11 Decubitus ulcer
Custom Medical Stock Photo, Inc.
Figure 7-12 Laceration
Gill/Custom Medical Stock Photo, Inc.
Figure 7-13 Shingles
Gill/Custom Medical Stock Photo, Inc.
Figure 7-14 Tinea pedis
SPL/Photo Researchers, Inc.
Figure 7-16 Hemangioma
Custom Medical Stock Photo, Inc.
Figure 7-20 Malignant melanoma
ISM/Phototake, Inc.
Figure 7-21 Kaposi’s sarcoma
Zeva Oelbaum/Peter Arnold, Inc.
Figure 7-22 Psoriasis
NMSB/Custom Medical Stock Photo, Inc.
Table 7-1 Comparison of Acne Vulgaris and Acne Rosacea
Figure 7-26 Allergy skin testing
SIU/Photo Researchers, Inc.
Figure 7-27 Botox injection
Suzanne Dunn/The Image Works
Figure 7-30 Liposuction
James King-Holmes/D. Mercer/Photo Researchers, Inc.
Figure 7-31 Skin grafts
Courtesy Martin R. Eichelberger, M.D., Children’s National Medical Center, Washington, DC
Figure 7-32 Subcutaneous injection