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Essentials of Anatomy and Physiology

Fifth edition
Seeley, Stephens and Tate

Chapter 4: Tissues, Glands, and


Membranes

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.1
Histology: Study of Body Tissues
 Cells are specialized for particular functions
 Tissues
 Groups of cells with similar structure and
function
 Four primary tissue types
 Epithelium
 Connective tissue
 Nervous tissue
 Muscle
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.41
Epithelial Tissues
 Locations:

 Body coverings (covers surfaces)


 Body linings (lines cavities)
 Glandular tissue (endocrine and exocrine)

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.42
Epithelial Tissues

 Functions
 Protection
 Absorption
 Filtration
 Secretion

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.42
Epithelium Characteristics

 Cells fit closely together


 Tissue has one “free” surface
 The deeper surface rests on a
basement membrane
 Avascular
 Regenerate easily

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.43
Classification of Epithelium

 Two methods:
[1] Number of cell
layers
 Simple – one layer
 Stratified – more than
one layer
Figure 3.16a

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Classification of Epithelium

 [2] Shape of cells


 Squamous – flattened
 Cuboidal – cube-shaped
 Columnar – column-like

Figure 3.16b

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.44b
Simple Epithelia

 Simple squamous
 Single layer of flat
cells
 Usually forms
membranes
 Lines body cavities
 Lines lungs and
capillaries
Figure 3.17a

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.45
Simple Epithelia
 Simple cuboidal
 Single layer of
cube-like cells
 Common in
glands and ducts
 Forms walls
of kidney tubules
 Covers ovaries
Figure 3.17b

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.46
Simple Epithelia

 Simple columnar
 Single layer of tall
cells
 Often includes
goblet cells
 produce mucus
 Lines digestive
tract Figure 3.17c

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.47
Simple Epithelia
 Pseudostratified
 Single layer, cells
vary in height
 Looks like a double
cell layer
 Sometimes ciliated
 Function in
absorption or
secretion

Figure 3.17d

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.48
Stratified Epithelia
 Stratified squamous
 Cells at the free
surface are flattened
 Function is protection
 Locations
 Skin
 Mouth
 Esophagus
Figure 3.17e

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.49
Stratified Epithelia

 Transitional
epithelium
 Shape of cells
depends upon
tissue stretching
 Lines organs of the
urinary system
Figure 3.17f

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.51
Glandular Epithelium
 Gland – one or more cells that secretes a
particular product

 Two major gland types


 Endocrine glands
 Ductless
 Secretions are hormones (Lots more later…)

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.52
Glandular Epithelium Slide 3.52

 Gland types, con’t…


 Exocrine glands
 Empty through
ducts to the
epithelial surface
 Include sweat
and oil glands
Goblet Cell: a single
celled gland

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings


Connective Tissue

 Found everywhere in the body


 Most abundant and widely distributed
tissues
 Functions
 Binds body tissues together
 Supports the body
 Provides protection
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.53
Connective Tissue Characteristics

 Variations in blood supply


 Some tissue types are well vascularized
 Some have poor blood supply or are
avascular
 Extracellular matrix
 Non-living material that surrounds living
cells

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Extracellular Matrix

 Two main elements


 Ground substance
 mostly water
 adhesion proteins
 polysaccharide molecules

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.55
Extracellular Matrix, main elements

 Fibers
 Produced by cells in matrix
 Types of Fibers
 Collagenous
 Elastic
 Reticular

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.55
Connective Tissue Types
 Bone (osseous tissue)
 Composed of:
 Bone cells in lacunae
(cavities)
 Hard matrix of calcium salts
 Organic component:
collagen fibers
 Used to protect and
support the body
Figure 3.18a

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.56
Connective Tissue Types

 Hyaline cartilage
 Most common
cartilage
 Composed of:
 Abundant collagen
fibers
 Rubbery matrix
 Most of fetal skeleton
Figure 3.18b

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Connective Tissue Types

 Elastic cartilage
 Provides elasticity
 Example: supports the external ear

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Connective Tissue Types

 Fibrocartilage
 Highly compressible
 Example: forms
cushion-like discs
between vertebrae

Figure 3.18c

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Connective Tissue Types
 Dense connective
tissue
 Main matrix element
is collagen fibers
 Cells are fibroblasts
 Examples
 Tendon – attach muscle
to bone
 Ligaments – attach bone
to bone
Figure 3.18d

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.59
Connective Tissue Types
 Areolar (loose)
connective tissue
 Most common
connective tissue
 Soft, pliable
 Contains all fiber
types
 Can hold excess fluid
Figure 3.18e

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.60
Connective Tissue Types
 Adipose tissue
 Areolar tissue specialized to store fat
globules
 Cells contain
large lipid deposits
 Functions
 Insulates the body
 Protects organs
 Site of energy storage
Figure 3.18f

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.61
Connective Tissue Types
 Reticular
connective tissue
 Delicate network of
fibers
 Forms stroma of
lymphoid organs
 Lymph nodes
 Spleen
 Bone marrow

Figure 3.18g
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.62
Connective Tissue Types

 Blood
 Blood cells in a
fluid matrix
 Fibers are visible
during clotting
 Functions in
transport

Figure 3.18h
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.63
Muscle Tissue

 Function to produce movement


 Three types
 Skeletal muscle
 Cardiac muscle
 Smooth muscle

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.64
Muscle Tissue Types

 Skeletal muscle
 Voluntary
 Attached to connective
tissue
 Cells are striated
 Cells have more than
one nucleus

Figure 3.19b

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.65
Muscle Tissue Types
 Cardiac muscle
 Found only in the
heart
 Involuntary
 Attached to other
cardiac muscle cells
 at intercalated disks
 Cells are striated
 One nucleus per cell
Figure 3.19c

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.66
Muscle Tissue Types

 Smooth muscle
 Involuntary
 Surrounds hollow
organs
 Attached to other
smooth muscle cells
 No visible striations
 One nucleus per cell Figure 3.19a

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.67
Nervous Tissue

 Neurons and
support cells
 Function to send
impulses to other
areas of the body
 Irritability
 Conductivity

Figure 3.20

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.68
Tissue Repair
 Regeneration
 Replacement by the same kind of cells
 Fibrosis
 Repair by dense fibrous connective tissue
 Type of repair determined by:
 Type of tissue damaged
 Severity of the injury

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.69
Regeneration of Tissues
 Tissues that regenerate easily
 Epithelial tissue
 Fibrous connective tissue and bone
 Tissues that regenerate poorly
 Skeletal muscle
 Cartilage
 Tissues replaced largely with scar tissue
 Cardiac muscle
 Nervous tissue within the brain and spinal cord

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 3.71

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