BASIC MEDICAL SCIENCE 1

(BONE AND MUSCLE)

HISTOLOGY OF
CARDIAC MUSCLE

Nama : Suci Ilhami Nurul

Hidayah
NPM : 160110180031
Fakultas Kedokteran Gigi
Universitas Padjadjaran
The Heart
Cardiac muscle
The Heart
Cardiac muscle
Position
The Heart
Cardiac muscle
Position
The Heart Cardiac Muscle has cross-striations and is composed
of elongated, often branched cells bound to one
Cardiac muscle another at structures called intercalated discs that are
unique to cardiac muscle. Contraction is involuntary,
vigorous, and rhythmic.
 Autonomic
Nervous System
The Heart
Cardiac muscle
Microscope at 400X
 The Heart
Cardiac muscle
Ultrastructure

(b) Muscle cells from the heart atrium show

TEM of cardiac muscle shows abundant
the presence of membrane-bound granules
mitochondria (M) and rather sparse sarcoplasmic
(G), mainly aggregated at the nuclear poles.
reticulum (SR) in the areas between myofibrils. T
These granules are most abundant in muscle
tubules are less well-organized and are usually
cells of the right atrium (~600 per cell). The
associated with one expanded terminal cistern of
atrial granules contain the precursor of a
SR, forming dyads (D) rather than the triads of
polypeptide hormone, atrial natriuretic factor
skeletal muscle. Functionally, these structures are
(ANF). X10,000.
similar in these two muscle types. X30,000.
The Heart
Cardiac muscle

S : Striation
I : Intercalated disc
N : Nucleus
 Bringing action
potential to the
sarcoplasmic
reticulum

allow action potential

to spread between
cells by allowing Consist of
movement of ions sarcomeres
 The Heart
Cardiac muscle
References

• Eroschenko, V. P., & Di Fiore, M. S. H. (2013). DiFiore’s

atlas of histology with functional correlations.
Lippincott Williams & Wilkins.
• Mescher, A. L., Junqueira, L. C. U., & Mescher, A. L.
(2018). Junqueira’s basic histology : text and atlas.
• Tortora, G. J., & Derrickson, B. H. (2008). Principles of
anatomy and physiology. John Wiley & Sons.