DENSITY & SPECIFIC GRAVITY

Density
Mass (g)
Density () = ---------------------
Volume (mL)

where M - mass or weight of substance

V - volume of substance

Specific gravity
Wt. of substance (g)
Specific gravity = ------------------------------------------
wt of equal vol. of standard (g)
Example: 10 mL of water weighs 10 g
10 mL of Hg weighs 136 g

m 136 g
  of Hg   13.6 g/mL
v 10 mL

wt. of the substance

sp.gr. 
wt. of an equal volume of water

wt. of 10 mL of Hg 136 g
sp.gr. of Hg    13.6
wt. of 10 mL of water 10 g
 DENSITY & SPECIFIC GRAVITY

Density (g/mL) = Specific gravity (no unit)

1 1 v
Specific = ------------ or ---------- or ---------
volume Sp. Gr.  m
DENSITY & SPECIFIC GRAVITY

1. If a prescription order requires 25

g of concentrated HCl (Density
1.18 g/ml), what volume should the
pharmacist measure?

2. What is the wt. of 60 ml of oil

whose density is 0.9624 g/ml?
DENSITY & SPECIFIC GRAVITY

3. Calculate the weight of 30 mL of

sulfuric acid whose density is 1.8
g/mL.

4. 1403 g of Nitric acid occupies a

volume of one liter. What is its
specific volume?
 METHOD
OF DETERMINING
THE SPECIFIC GRAVITY
OF LIQUIDS
A. Pycnometer Method (Leach Pycnometer):

• most accurate method for the

determination of the sp. gr. of
liquids

Ex. Determine the specific gravity

of alcohol

Wpyc w/ alc. - Wpyc empty

Sp.gr. of alc. 
Wpyc w/ water - Wpyc empty
It’s TIME to solve your problem set.

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