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Farmakologi Antiprotozoa
Farmakologi Antiprotozoa
PHYLUM PHYLUM
SARCOMASTIGOPHORA CILIOPHORA
PHYLUM
APICOMPLEXA
Entamoeba
Trypanosoma
histolitica Plasmodium Paramecium
gambiense
vivax Caudatum
Entamoeba Trypanosoma
coli cruzi P.malariae Balantidium
coli
ENTAMOEBA HISTOLITICA
• -Trypanosoma gambiense,
• -Trypanosoma rhodesiense,
• -Trypanosoma cruzi.
It is pathogen of leishmaniasis
(cutaneous or visceral).
Leishmania tropica is the
causative agent of cutaneous
leishmaniasis which is transmitted
to humans by sand-flies of
Phlebotomus genus.
At the place of sand-flie’s sting a
red papular appears and then ulcer
forms. The ulcer cicatrizes and
forms a scar that remains after
treatment.
Leismania domovani causes visceral leishmaniosis (or Kala-azar).
The parasite attacks blood vessels, lymphatics, spleen, liver, red
bone marrow. The disease manifestes itself by fever, enlargment
of the spleen, liver, by rheumatic pains.
LAMBLIA (GIARDIA).
• - adult forms-trophozoites,
• - cysts.
Gol. Kuinolin :
Kuinine, Kuinidine, Gol. Antibakteri :
Primakuin, Klorokuin, Sulfonamid,Tetrasiklin,
Amodiakuin, Meflokuine, Spiramisin, Azitromisin,
Halofantrin, Klindamisin, Rifampisin
primakuine,piperakuin
Mekanisme
kerja
Golongan Kuinolin
Golongan Artemisin
Malaria berat
Amebiasis adalah penyakit parasit yang manifestasinya pada saluran pencernaan yang spesifik.
• Dry mouth
• Metallic taste in the mouth and,
Commonly
• Nausea occurs
• Headache