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Pre Eclampsia and Eclampsia: A Review and Recent Updates
Pre Eclampsia and Eclampsia: A Review and Recent Updates
Pre Eclampsia and Eclampsia: A Review and Recent Updates
PAMELA FLOOD
PROFESSOR OF ANESTHESIOLOGY,
PERIOPERATIVE AND PAIN MEDICINE
STANFORD UNIVERSITY
Preeclampsia / eclampsia
Expression of placental anemia of
mother
Antenatal giat-
Influenced mother.
Small for gestational
age, fetal effects
Vegetables abruption is
an expression in the
cake is the effect on the
placenta rau.Abruption
endothelial
Uterus
A - Not Pregnant
B - Pregnancy, and not greater than the smooth muscle layer
Maximum relaxation
Prof. Moorefirst, Allshouse AA2, Post ALfirst, Galan HLfirst, Heyborne Dealersfirst. Early
initiation of low-dose aspirin for reduction in preeclampsia risk in high-risk
women: a secondary analysis of the High-Risk MFMU Aspirin Study. J
Perinatol. 4 Dec 2014
statins - Prevent?
What?
Drill! - not statins are classified into
categories according to the old classification
X by the FDA?
True- canned fearing reduce cholesterol in
children.
Several studies on the effects of cases
teratogenicity of the old station
Not particularly used in pregnant women should not
be the public-private investments.
Studies after being put on the market demonstrated
no increased risk in humans.
Why Statins?
Stop circulation
Treatment Before Birth
eclampsia
Emergency
airways
Respiratory
propofol
Treatment of Hypertension
Labetalol is recommended to use first-hand.
PK major changes in pregnant women.
Sudden increase clearance.
Thehalf-life of 1.7 hours compared to 6-8 ½ h in
women who are not pregnant.
Distance dose should be shortened.
Metoprolol time peak effect also reduced
Atenolol oral absorption increases with increased
offset ups should renal dose constant.
Increase vasoconstriction
May be accompanied by heart failure
Treatment can reduce afterload
nifedipine
hydralazine
Hypertension induction:
Regional anesthesia
The old idea that affect cardiovascular risk is a
contraindication for regional anesthesia in patients with
preeclampsia.
By vasodilation occurs when under the effect of
sympathetic blockades overcome the lack of circulation
volume and vasoconstriction
However, it should follow the evidence suggests that
blood pressure less volatile in women with preeclampsia
compared with normal women lobby when the sensory
block.
Perinatal, the short-term medication is used more often
due to the rapid changes in translation.
Pant MfirstFong R, Scavone B. Prevention of peri-induction in preeclamptic
hypertension Patients: a the focused review.Anesth Analg. 2014 Dec; 119 (6):
1350-6.
Regional anesthesia and
Preeclampsia
Selected regional anesthesia more
Reduce maternal mortality
Reduce child mortality
Maintain blood flow placenta uterus.
Possible contraindications when coagulopathy.
Low platelet
HEELP
Ankichetty SP, Chin KJ, Chan VW, Sahajanandan R, Tan H, Grewal A, Perlas A.
Regional anesthesia in pregnancy induced hypertension Patients with. J Clin
Pharmacol Anaesthesiol. 2013; 29: 435-44
Hypertension induction
Anesthesia
Beta blockers
Esmolol - is preferred in surgery as a fast-acting and short.
Labetolol - Can cause hypotension and bronchospasm.
metoprolol
nitroglycerine
nitroprusside
Cyanide poisoning if prolonged use
hydralazine
Onset time delay effects (5-10 minutes)
Long-acting (1-4 h)
Headache
drowsiness
Vomit
Changing perceptions
Visual disturbances
Convulsions