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Tugas Nutrigenomic
Tugas Nutrigenomic
Tugas Nutrigenomic
dibawakan oleh :
dr. Indrawaty Alimuddin / C175172005
Blood lipid Modifiable risc
levels factors for CAD
Changes in level
or function of
protein
the ɛ4 contains an arginine
SNPs Codon
112
Encoded by APOE
genetic locus locus
Codon
158
The ɛ2 allele contains a cysteine21
D
E
T
E
R
the effect of M
I an individual’s
diet on blood N
E
genetic
lipid levels D
makeup
B
Y
• T polymorphism at the hepatic lipase (LIPC) locus/ T allele is
associated with elevated serum HDL-C concentration in
many studies
polymorphisms at the
peroxisome proliferator-
activated receptor-a
• substitution • results in a
of saturated (PPAR-a) locus interact
• unsaturated decrease in
fat in the serum HDL- with dietary
fat polyunsaturated fatty
diet C concen-
tration acid intake to determine
HDL-C concentrations in
Chinese women
GENE-ENVIRONMENT INTERACTIONS
AND THE DIABETES EPIDEMIC IN
INDIA
2000 2030