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Antepartum Hemorrhage
Antepartum Hemorrhage
(APH)
Definition:
• Vaginal bleeding after 24weeks and before the delivery of the fetus.
• It complicates (3-4%) of all pregnancies.
• It is an obstetric emergency because it endanger the life of both the
mother and fetus.
• Hemorrhage remain the most frequent cause of maternal deaths.
• Mild= <50 mL loss of blood, Major= 50-1000mL loss, Massive=
>1000mL loss.
• Bleeding >1 occasion regarded as recurrent APH.
Etiology:
• CBC
• DIC Workup
• (Platelets, PT, PTT (partial), Fibrinogen, D-Dimer).
• Type and Crossmatch
• US (location of Placenta)
A. MAJOR
• This is clinically obvious and may result in the death of the fetus.
• It is also life-threatening to the mother and usually involves
separation of more than one-third of the placenta.
B. MINOR
• Premature separation of small areas of the placenta may result in
placental infarcts.
• Several small abruptions may precede a large abruption.
Moderate Severe
MILD abruption Abruption
Abruption Tachy., Variability Severe late
Normal FHR Mild late deceleration, brady,
decelerations death!
Painful
Abruptio placenta
Placental Location
Normal
Not Lower segment
Ob-Gyn Key phrases
Late Abruptio
pregnancy bleeding Abruptio
Abruptio
placent
a
Painful Late
placent
pregnancy bleeding
Obstetric DIC
placenta
a
Ob-Gyn key TRIADS
Abruptio placenta
Late trimester painful bleeding
Normal placental implantation
DIC
Risk factors
1. Idiopathic: (Majority).
2. There is an association with defective trophoblastic invasion, as with pre-
eclampsia and intrauterine growth restriction.
3. Direct trauma e.g. RTA and external cephalic version.
4. High parity.
5. Uterine over distention (as in polyhydramnios and multiple pregnancy).
6. Sudden decompression of the uterus e.g. after delivery of 1st twin or release
of polyhydramnios.
7. Hypertension.
8. Smoking.
9. Folic acid deficiency.
Diagnosis
A. MAJOR
• Women present with abdominal pain and varying degrees of shock.
• The blood loss that is visible (revealed haemorrhage) is often less
than the degree of shock.
• On examination:
1. The uterus is woody hard; due to a tonic contraction.
2. The fetal parts cannot be felt.
3. The fetus may be dead.
Clinical Presentation:
B. MINOR
• Minor abruptions are often not diagnosed until after
delivery.
Maternal complications:
• Acute Tubular Necrosis
• DIC.
• Couvelaire uterus: refers to blood extravasating between the myometrial fibers.
• Postpartum Hemorrhage
• Feto-maternal haemorrhage.
• Maternal mortality
• Recurrence: 10% After 1st attck, 25% After 2nd attck
Fetal complications:
• Impaired fetal growth and/or hypoxic ischaemic encephalopathy (HIE)……C.P
Blue
Uterus
Couvelaire Uterus
Placenta
Previa
Placenta previa (P.P.)
Means implantation of the placenta in the lower uterine segment (28 wks).
• Usually the lower implanted placenta atrophies and the upper placenta
hypertrophies, resulting in migration of the placenta.
• At term placenta previa is found in only (0.4-0.8%) of pregnancies.
• Symptomatic placenta previa occurs when painless vaginal bleeding
develops through avulsion of the anchoring villi of an abnormally
implanted placenta as lower uterine segment stretching occurs in the
latter part of pregnancy.
• Bleeding from placenta previa account for about 30% of all cases of APH.
Predisposing Factors:
1. Multiple gestation.
2. Previous C/S scar.
3. Multiparity
4. Previous placenta previa
5. Assisted conception
6. Endometritis
7. Uterine structural anomaly (e.g. septate uterus).
8. Smoking
9. Fetal Cong. Anomaly or Malpresentation
Placenta PREVIA
Mechanism of “MIGRATION”
Differential Atrophy
& Hypertrophy
Prevalence of Placenta PREVIA
At 16 Weeks 20 %
At 40 Weeks 0.5 %
Why the difference?
TROPHO TROPISM
Placental movement
1. Theonplacenta
Factors covers
2nd trimester the internal
ultrasound os with
are associated an
with the persistence of a placenta previa in the 3rd
overlap
trimester:
of more than 1.5 cm.
Painless
Ob-Gyn Key phrases
Painless late-
trimester bleeding
Placenta previa
Ob-Gyn key TRIADS
Placenta Previa
Late trimester bleeding
Low segment plac. implant
No pain
Placenta PREVIA
Pathophysiology of bleeding
Avulsion of villi
Stretching of
lower uterine segment
Grading of placenta previa:
• If placenta previa occurs over a previous uterine scar, the villi may
invade into the deeper layers of the decidua basalis and
myometrium, This can result in intractable bleeding requiring
cesarean hysterectomy.
Complications of placenta previa:
B- Fetal complications:
The perinatal mortality of patients with placenta previa is higher than the
general population and this is related to:
1. Prematurity (which is the main cause).
2. Higher incidence of IUGR (about 20% of pregnancies with placenta
previa) Malpresentation (in 30% of cases).
3. Higher risk of preterm premature rupture of membranes.
4. The presence of vasa previa which carry a perinatal mortality of 75%.
Advice for the
patient
• After several days without bleeding, she may be ambulate and even
discharged if she lives nearby.
Vasa Previa
ROM
Vaginal bleeding
Fetal bradycardia
What is the diagnosis &
Why?