Pre / Post Questions

for
“The Case of the Druid Dracula:
Clicker Case Version”
by
Norris Armstrong, Terry Platt, and
Peggy Brickman
PQ1: The strands in a DNA double helix are
held together by hydrogen bonds between
which one of the following?
A: The pentose sugars on one chain and the
phosphates on the other chain.
B: The pentose sugars on one chain and the pentose
sugars on the other chain.
C: The phosphates on one chain and the nitrogenous
bases on the other chain.
D: The nitrogenous bases on one chain and the
nitrogenous bases on the other chain.
E: The phosphates on one chain and the phosphates on
the other chain.
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PQ2: Below is one strand of a double
stranded DNA molecule. What is the
sequence of the other strand in this
molecule?

5′-ATTCGACGATG-3′

A: 5′-TAAGCTGCTAC-3′
B: 3′-TAAGCTGCTAC-5′
C: 5′-ATTCGACGATG-3′
D: 3′-ATTCGACGATG-5′

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PQ3: The steps listed below are components of copying
double-stranded DNA. Place them in order from first to
last.
1: Synthesis is initiated on the 3-hydroxyl group of the
primer.
2: Two strands of a duplex DNA molecule are separated.
3: DNA polymerase makes a DNA chain using an existing
chain as a template.
4: A primer base-pairs with the complementary region of
the DNA to be copied.
A: 1, 2, 3, 4
B: 3, 4, 1, 2
C: 2, 4, 3, 1
D: 4, 3, 1, 2
E: 2, 4, 1, 3
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PQ4: You need to make copies of this DNA
strand:
3′-GCAACTGAAATAGCTTTGACCCC-
5′
5′-CGTTGACTTTATCGAAACTGGGG-
3′
Which of the primers below would help you do
this?

A: 3′-GCAACT-5′
B: 5′-CGTTGA-3′
C: 3′-CGTTGA-5′
D: 5′-GCAACT-3′

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PQ5: How would DNA synthesis be
affected if primers were not available?
A: The template strands would not be able to
separate.
B: Synthesis would result in many small segments
of DNA instead of a complete molecule.
C: Synthesis of a complementary DNA chain would
begin but would not be able to finish.
D: Synthesis of a complementary DNA chain would
not initiated.
E: The DNA strands produced by synthesis would
not be complementary to the template strands.
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PQ6: A suspect matches two STRs in a DNA
fingerprint. If you assume one STR is found in one
out of every 3,000 people and the other one out of
every 3, the largest group this fingerprint could be
reasonably expected to identify a specific
individual from could be:

A: Your friend’s apartment (3 people).

B: A large class (~300 people).
C: One of the dorms on campus (~1,000 people).
D: A large part of campus (~9,000 people).
E: A nearby city (~100,000 people).
F: There is too little certainty at any of these scales.
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