Scribd Logo
Upload

Welcome to Scribd!

  • Nucleosome Model

    Uploaded by

    Kiran verma
    12 views2 pages
    The document describes the structure of B-DNA and the higher organization of DNA. B-DNA has a right-handed double helix structure with a diameter of 20 angstroms and strands that are antiparallel. DNA is organized into nucleosomes which form fibrils and chromatin fibers through winding and supercoiling, condensing the DNA over 10,000-fold into chromosomes that package the human genome of 7 billion base pairs.

    Original Description:

    NUCLEOSOME MODEL

    Original Title

    Nucleosome model

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document describes the structure of B-DNA and the higher organization of DNA. B-DNA has a right-handed double helix structure with a diameter of 20 angstroms and strands that are antiparallel. DNA is organized into nucleosomes which form fibrils and chromatin fibers through winding and supercoiling, condensing the DNA over 10,000-fold into chromosomes that package the human genome of 7 billion base pairs.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    12 views2 pages

    Nucleosome Model

    Uploaded by

    Kiran verma
    The document describes the structure of B-DNA and the higher organization of DNA. B-DNA has a right-handed double helix structure with a diameter of 20 angstroms and strands that are antiparallel. DNA is organized into nucleosomes which form fibrils and chromatin fibers through winding and supercoiling, condensing the DNA over 10,000-fold into chromosomes that package the human genome of 7 billion base pairs.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 2

    B-DNA Structure

    20 Å

    GC
    AT

    CG
    TA

    Minor
    CGCGTTGACAACTGCAGAATC Groove
    34 Å AT
    GC
    TA
    Major
    Groove
    TA
    3.4 Å CG
    AT

    Strands are
    antiparallel GC
    CG
    GC
    HIGHER ORGANIZATION OF DNA
    • DNA is wound over histones to form nucleosomes.

    • A group of nucleosomes form DNA fibrils.

    • 6 such fibrils are supercoiled to form chromatin


    fibers.

    • Chromatin fibers are supercoiled to form loops.

    • Loops are condensed to form chromosomes.

    • DNA is condensed or compressed 10,000 folds to


    form a chromosome.

    • Human diploid genome consists of 7x109 base pairs.

    You might also like