Anemia by DR Rashid

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ANEMIA

By Dr. Rashid
WHAT IS ANEMIA?

 Anemia is decrease in the level of Haemoglobin in blood below


the reference level for the age and sex of individuals.
 Or
 Anemia is defined as a state in which Haemoglobin
concentration or red cell volume is below the mean for age and
sex.
 Actually anemia is not the disease but is a symptom of other
disorders.
GENERAL CHARACTERISTICS

• Patient may be asymptomatic

 Non specific symptoms include : Fatigue, headache, breathlessness,


Palpitations, Tachycardia, Systolic flow murmur, cardiac
failure,Glossitis,Angular cheilosis

 Specific symptoms : Koilonychia in Iron deficiency anemia, jaundice in


haemolytic anemia, bone deformities in thalassemia.
CAUSES
TYPES OF ANEMIA
 Anemia is classified on the basis of MCV

Microcytic Anemia Macrocytic Anemia Normocytic Anemia


(MCV below 80) (MCV 80 – 100) (MCV 80-100)

• Iron deficiency • Vitamin B-12 • Aplastic Anemia


anemia deficiency • Leukemia
• Thalassemia • Folate deficiency • Hereditary
• Anemia of • Liver diseases spherocyposis
chronic disease • Hypothyroidism • Autoimmune
• Sideroblastic diseases
anemia • Haemolysis
• Blood loss
LAB. INVESTIGATION OF ANEMIA
 CBC and RBC morphology
 Peripheral blood film
 ESR
 Bone marrow exam.(only when indicated)
 Urine RE , Stool RE
 Upper GI Endoscopy
 Hemoglobin electrophoresis
MANAGEMENT

Care Objectives
 Determine the Cause of anemia
 The etiology is often multifactorial; even when there is an obvious cause, investigation of
serious underlying causes (e.g.cancer in adults) is recommended.
 Aim of Treatment
 Individualize disease-specific management depending on underlying cause.
 Lifestyle Management
It is recommended that patients with anemia should change the lifestyle to replenish the
deficiencies e.g in iron deficiency anemia (iron ) , Vitamin B-12 , Folic acid
TREATMENT

 Best treatment is to treat underlying cause of anemia..

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