GALL BLADDER

• It is a hollow system that sits just beneath

the liver
• small organ that aids mainly in
fat digestion &
concentrates bile produced by the liver.
 MICROSCOPIC LAYERS:
• The different layers of the gallbladder are as follows:[4]
• The epithelium, a thin sheet of cells closest to the
inside of the gallbladder
• The lamina propria, a thin layer of loose connective
tissue (the epithelium plus the lamina propria form the
mucosa)
• The muscularis, a layer of smooth muscular tissue
that helps the gallbladder contract, squirting its bile
into the bile duct
• The perimuscular ("around the muscle") fibrous
tissue, another layer of connective tissue
• The serosa, the outer covering of the
gallbladder that comes from the
peritoneum, which is the lining of the
abdominal cavity
• Unlike elsewhere in the intestinal tract, The
wall of the bladder does not have a
muscularis mucosae and submucosa.
 HISTOLOGICAL FEATURES
• The mucosa is lined by tall columnar cells.
• The mucosa is highly folded and some of
folds might look like villi, and look like
absorptive cells in the intestine but in gall
bladder no goblet cells are present.
 
• Underneath the epithelium is the lamina
propria.
• The muscularis externa (muscle layer)
contains bundles of smooth muscle cells,
collagen and elastic fibers.
• A serous covering (serosa) lined by
flattened mesothelium is present external
to the muscularis