INTERVENTIONAL

PULMONARY
Kevin Lumowa
 Reference 1
 Jablonski S, Kordiak J, Wcislo S, Terlecki A, Misiak P, Santorek-Strumillo E, Lazarek J, et al.
Outcome of Pleurodesis Using Different Agents in Management Prolonged Air Leakage
Following Lung Resection. Clin Respir J 2018;12(1):183-192
 Reference 2
 Olesen WH, Katballe N, Sindby JE, Titlestad IL, Andersen PE, Lindahl-Jacobsen R, Licht
PB. Surgical Treatment Versus Conventional Chest Tube Drainage in Primary Spontaneous
Pneumothorax: A Randomized Controlled Trial. Eur J Cardiothoracic Surg 2018;54(1):113-
121

LIST OF ARTICLES (USE ONLY

STUDIES)
Pleurodesis is a procedure that is done to treat repeated collapsed lungs or fluid bulld-up
between the lung and chest wall lining that will not go away.

A drug is put in the pleural space (space between your lung and chest wall) to keep your lungs
and chest wall stuck together to prevent air or fluid from collecting in the pleural space.

Pneumothoraces and air leaks in the lungs can be a result of chest tube placements, lung
resections, bronchopleural fistulas, etc.

PLEURODESIS
 Purpose: Evaluate two methods of chemical pleurodesis efficacy
performed with a water soluble tincture of iodine and doxycycline
applied by chest tube drainage in PAL treatment lasting more than 5
days in patients after lung resection.
 The study authors have used iodine for intrapleural pleurodesis for
patients with persistent air leak (PAL). Polyvinylpyrrolidone was more
commonly used than iodine, therefore there wasn’t much literature on
describing the use of iodine for pleurodesis.

ARTICLE 1 CRITIQUE (JABLONSKI ET

AL 2015. OUTCOME OF
PLEURODESIS…)
 Patients with prolonged alveolar air leaks were split into 3 groups for
treatment: doxycycline group, iodine group, and drainage group. The
control group was patients treated by chest tube drainage alone.
 The main outcomes were postoperative air leakage, which was
measured in mL/min, and drainage duration.
 This variable was selected for the main outcome to obtain objective
data about PAL intensity of the different treatments for it.

CONTINUED
ARTICLE 1 RESULTS
 Purpose: There is a lack of evidence for whether patients may benefit
from surgery following their first episode of primary spontaneous
pneumothorax (PSP).

 The authors were wondering if there are high-risk patients of

recurrence, who should be offered primary preventive care surgery
following the first episode of PSP and see if there are any predictors to
identify these high-risk patients.

ARTICLE 2 CRITIQUE (OLESEN ET AL

2018. SURGICAL TREATMENT
VERSUS...)
 Patients with their first episode of PSP verified by chest x-ray were
recruited for the study. Initial treatment was done for all patients, and
based on the presence of bullae, patients were randomized into either
conventional chest tube management or a video-assisted thoracoscopic
surgery (VATS) bullectomy with mechanical pleurodesis during the initial
admission or as an elective procedure within 4 weeks.

 The primary outcome was ipsilateral recurrent spontaneous pneumothorax

verified by chest radiography. Secondary outcomes were complications
and length of hospitalization
ARTICLE 2 RESULTS
ARTICLE 1 ARTICLE 2

• Results showed that iodine pleurodesis could
be a possible treatment for persistent air leak
after lung resection, showing favorable
results compared to traditional drugs used for
pleurodesis
• Results showed that patients admitted with first
presentation of primary spontaneous
pneumothorax had a significant lower recurrent
rate following VATS with mechanical
pleurodesis when compared to conventional
chest tube treatment.

Both articles’ purposes are based off a lack of literature for the respective information they
wanted to find. The results of each studied helped expand the knowledge base for pleurodesis
and the extent of it’s use.

COMPARE AND CONTRAST