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Phytochemical Mahkota Dewa
Phytochemical Mahkota Dewa
Phaleria macrocarpa
Fatin Nur
Introduction
Human diet contain varied
natural mutagens and
carcinogens generated by
oxygen radicals.
Causes DNA damage and
mutation that leads to:
a.cancer
b.heart disease
Phaleria macrocarpa uses as
herbal medicine is exploited.
It has anti-oxidant that
simultaneously act as anti- P.Macrocarpa tree of Thymelaceae family
cancer. (Phaleria macrocarpa,2013).
P.Macrocarpa parts: a)small flower bud, b)green tapering
leaves, c)un-ripened fruit and d)fully grown red fruit. (Altaf
R., et. al, 2013).
Problem statement:
Phytochemical constituents and effect are still relatively unknown and
incomplete.
Objective of research:
i. To extract and isolate pure compounds from P.macrocarpa through
column chromatography and thin layer chromatography
Isolation :
TLC and CC
Purification:
Recrystallization process
Material & Methodology
Sample preparation:
-Flowers, stems, leaves and seeds obtained are grounded
into powder.
Calculate mortality
rate to determine
toxicity.
DppH radical scavenging activity for anti-oxidant