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  • Skin Conditions: SPHMMC Department of Surgery

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    Worku Kifle
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    The document discusses pre-malignant skin conditions including actinic keratosis (solar keratosis). Actinic keratosis presents as scaly erythematous papules or plaques on sun-exposed skin that have a sandpaper-like texture. Risk factors include increased age, light skin/hair/eyes, immunosuppression, and certain genetic syndromes. Actinic keratosis has a risk of transforming into squamous cell carcinoma, especially with persistence or in immunosuppressed individuals. The document also mentions malignant melanoma and its ABCDE characteristics for identifying potentially malignant moles.

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    DER

    Original Title

    Common Derma

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    The document discusses pre-malignant skin conditions including actinic keratosis (solar keratosis). Actinic keratosis presents as scaly erythematous papules or plaques on sun-exposed skin that have a sandpaper-like texture. Risk factors include increased age, light skin/hair/eyes, immunosuppression, and certain genetic syndromes. Actinic keratosis has a risk of transforming into squamous cell carcinoma, especially with persistence or in immunosuppressed individuals. The document also mentions malignant melanoma and its ABCDE characteristics for identifying potentially malignant moles.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    16 views8 pages

    Skin Conditions: SPHMMC Department of Surgery

    Uploaded by

    Worku Kifle
    The document discusses pre-malignant skin conditions including actinic keratosis (solar keratosis). Actinic keratosis presents as scaly erythematous papules or plaques on sun-exposed skin that have a sandpaper-like texture. Risk factors include increased age, light skin/hair/eyes, immunosuppression, and certain genetic syndromes. Actinic keratosis has a risk of transforming into squamous cell carcinoma, especially with persistence or in immunosuppressed individuals. The document also mentions malignant melanoma and its ABCDE characteristics for identifying potentially malignant moles.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 8

    Skin Conditions

    SPHMMC DEPARTMENT OF SURGERY

    08/17/2020
    Pre-Malignant Skin Conditions
    • ACTINIC KERATOSIS (SOLAR KERATOSIS)
    • Ill-defined, scaly erythematous papules or plaques on a background of sun-damaged
    skin
    • sandpaper-like, gritty sensation felt on palpation, often easier to appreciate on
    palpation rather than inspection
    • Sites: areas of sun exposure (face, ears, scalp if bald, neck, sun-exposed limbs)
    • UV-induced p53 gene mutation
    • risk factors: increased age, light skin/eyes/hair, immunosuppression, syndromes such
    as albinism or xeroderma pigmenotsum, M>F
    • risk of transformation of AK to SCC (~1/1,000), but higher likelihood if AK is persistent
    • risk factors for malignancy: immunosuppression, history of skin cancer, persistence of the AK

    08/17/2020
    08/17/2020
    08/17/2020
    08/17/2020
    08/17/2020
    08/17/2020
    malignant characteristics of a mole: “ABCDE” mnemonic
    sites: skin, mucous membranes, eyes, CNS

    08/17/2020

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