Premedication

Dr.M.Kannan MD DA
Professor And HOD
Department of Anaesthesiology
Tirunelveli Medical College
 Premedication

• Drugs administer 1-2 hours before

induction of Anaesthesia
 Why Premedication
• To Allay anxiety and
fear

• Non Pharmacological
-Assurance &Raport

– Pharmacological
-Benzodiazepanies
-Diazepam
-Medazolam
-Lorozepam
 Why Premedication
• To Reduce Secretion

• Salivary secretion
• Broncheal secretion
• Anticholinergic drug-Atropine
-Glycopyrolate
Tachycardia Hyperthermia
 Why Premedication
• Enhances Hypnotic
effect of General
Anaesthetic Drugs

-Less amount volatile

Anaesthetics and
nacotics
 Why Premedication
• Reduces
Postoperative Nausea
and Vomiting

• Aspiration
• Psychological trauma
 To Prevent Vomiting
• Metachlorpropamide

• Ondansetron

• Ranitidine
 Why Premedication
• Produce Amnesia

• Benzodiazepine group
-Diazepam 0.1-0.2mg/kg
-Medazolam0.05mg/kg
-Lorozepam
 Why Premedication
• Gastric Content Volume ph -alkaline

• Metoclopramide-
• Sodium citrate
 Why Premedication
• Attenuate sympathetoadrenal response
-Laryngoscopy
 Why Premedication
• Attenuate vagal reflex
• ? Bradycardia
• Traction of eye muscle
in squint surgery
- Repeated administration succinylcholine

-Induction of Anaesthesia with halothane

-Lighter plane of Anaethsia

 Why Premedication
• Allay anxiety and fear
• Reduce Secretion
• Enhances Hypnotic effect of General
Anaesthetic Drugs
• Reduces Postoperative Nausea and Vomiting
• Produce Amnesia
• Gastric Content Volume ph -alkaline
• Attenuate vagal reflex
• Attenuate sympathetoadrenal response
 What Drugs ?
• Antisailagoge –Atropine/Glycopyrolate

• Sedative –Morphine
-Pethedine
-Benzodiazepaines
-Barbiturates
Antiemitics -Metachlorpropamide/Ondonsetron

• Disease Specific Drugs

 Can we Give Fixed Pre.Med
NO
Cardiac –Avoid anticholinergics & Stiff
sedatives
Thyrotoxicosis- Avoid anticholinergic
Head injury- Avoid sedatives
Airway obstruction- Aviod sedatives
Pregnancy- Avoid sedatives