OptiBond™ Versa

A New Paradigm in Dental Bonding

1
OptiBond™ Versa

Agenda
SECTION TOPIC
1 Limitations of Bonding Agents
2 A Solution to the Bonding Dilemma
3 Core Technology Review
4 Solving Bonding Agent Limitations
5 The Six Pillars of Bonding
6 Conclusion

2
 OptiBond™ Versa
SECTION 1

Evolution of Bonding Agents

3
 OptiBond™ Versa
EVOLUTION OF BONDING AGENTS

Dental Bonding Agent Uses

Dental Procedures Requiring
Bonding Agents (millions)*

• In 2000, dental bonding agents bonded

2.5 1.1
100 million restorations
38
• With this many restorations, bonding
agents must provide predictable and
consistent performance
86
• Adhesion and sealing of the tooth
are critical for success in both direct
and indirect procedures
Direct Restorations/Core Build ups
Resin/Ceramic Crowns
Veneers
Ceramic/Porcelain Inlay/Onlay

4
*American Dental Association. The 2000 Survey of Dental Services Rendered. Published 2002.
 OptiBond™ Versa
EVOLUTION OF BONDING AGENTS

1960s
1960s & 1970s 1stst & 2nd
nd generation

No acid-etching on dentin. Relied on

• Dentin etching not recommended
adhesion to smear layer. Weak bond strength. • Adhesion was to smear layer, which was weak
BONDING AGE NT TIMELINE

1980s 3rd
rd Generation
• Modified smear layer
No acid etching on dentin. Separate primer.
Moderate bond strength. Marginal staining
• Marginal staining was still pre-dominate
1980s

1990s Early 1990s 4th

th Generation

Acid etching on dentin. Separate primer.
Hybrid layer of dentin/collagen. Dentin seal.
Wet bonding. Higher bond strength.
Complicated bonding steps.
• Incorporated penetrating primers and higher filler
loads
• Increased bond strengths
• Complicated bonding steps

Mid 1990s 5thth Generation

Combined primer & adhesive. High bond

strengths. • Combined primer and adhesive, convenient
• Technique/post-op sensitivity and acidic bonding agent
Late 1990s 6th
th Generation

Self-etching primers. Low sensitivity. Lower

bond strength vs.. 4thth and 5th • Self-etching primers developed, reduced sensitivity
• Lower bond strength on enamel, film thickness
Mid 2000 7th th Generation

Combines etching, priming, & bonding. Low

bond strength to enamel. • Combines self-etch primer and adhesive for easy use
Today • Low enamel strengths and acidic bonding agent
5
 OptiBond™ Versa
SECTION 1

Limitations in Bonding Agents

6
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Limitations Are Present in All Bonding Agents

Reduced Enamel Bond Post-Op Excessive Film

Etch/Adhesion Incompatibilities Sensitivity Thickness

4th Gen

5th Gen

6th Gen

7th Gen

7
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Reduced Enamel Etch and Adhesion of Self-Etch

Phosphoric Acid 50,000X 6th Generation 50,000X 7th Generation 50,000X

Self-Etch (6th/7th Gen) Bonding Agents Are:

• Mildly acidic
• Lower etch quality
• Lower enamel bond strength
• Require enamel etching
8
Swift E, et al, J Esthet Restor Dent. 2011 Dec;23(6):390-6. doi: 10.1111/j.1708-8240.2011.00465.x. Epub 2011 Oct 17.
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Post-Operative Sensitivity of Total-Etch

Collagen fibers
Open space
collapsed and
between
space collagen
between
fibers maintained
collagen fibers
by water
closed when over-
dried

Hot/Cold
Stimulus

9
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Bond Incompatibilities of 1-Bottle Systems

Self-Cured Resin Cement/Core Material

Tertiary Amine (Base)
• PFM /PFZ
• Metal Crowns
• Opaque Restorations
• Bulk-Fill Composite Core Material

Acid/Base Reaction and Phase Separation

Single Bottle Adhesive System

Acidic • 5th Generation Total-Etch Adhesive
• 7th Generation Self-Etch Adhesive

10
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Bond Incompatibility
at “Cement/Adhesive/Dentin” Interface under Opaque Restorations

BPO/°Amine
Cement not in contact with adhesive Initiator
(Curing not affected by adhesive)
Cement
Cement Layer in Contact with Acidic Adhesive
Cement fails to cure or Hydrophobic
Initiators: BPO + Tertiary Amine Base
cures poorly – no/poor bonding
Phase Separation
Acidic Monomer (H+) /Water
in Air-Inhibited Layer (uncured) Hydrophilic
Adhesive
Cured Adhesive Layer Primer/Adhesive
Combined (Acidic)
Tooth Dentin (water)

Poor cuing at the adhesive/resin cement interface

Phase separation at the adhesive/resin cement interface

Compromised Adhesion 11
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Excessive Film Thickness of Adhesive Layer

Root Cause
>35μm It is the high viscosity
Non-radiopaque • Due to lack of solvent
adhesive layer • Higher filler loading

What Are Some Issues?

• Limited indirect use
• Pooling
• Carries misdiagnosis

SEM magnified of ClearFil SE Bond at 2,000X

12
 OptiBond™ Versa
Limitations OF BONDING AGENTS

Multiple Bottles: Direct Result of Limitations

DIRECT/CORE INDIRECT

Ceramic Veneers Porcelain/Composite Metal or PFM Crown

13
 OptiBond™ Versa
SECTION 2

OptiBond Versa: A Solution

to the Bonding Dilemma

14
 OptiBond™ Versa
A SOLUTION TO THE BONDING DILEMMA

OptiBond Versa Product Highlights

 Self-etch
 Only 2 components
 Light-cured, 15% filled (including
nano fillers)
 Indicated for direct and indirect
restorative procedures
 Separate hydrophilic self-etching
primer with enhanced etching
capabilities
 Separate hydrophobic adhesive to
maximize material compatibility,
increase strength and promote bond
durability
15
 OptiBond™ Versa
A SOLUTION TO THE BONDING DILEMMA

OptiBond Versa Indications

DIRECT BONDING
Light-cured composite and compomer restorations

Composite/ceramic/metal repairs

Cavity sealing for amalgam restorations

Sealing of hypersensitive and/or exposed root surfaces

Core build-ups (self-cured, light-cured, or dual-cured)

INDIRECT BONDING
Veneers
Porcelain, composite, and metal-based (including zirconia-
based and alumina-based) inlays, onlays, crowns, bridges
Endodontic posts

Cavity sealing as a pretreatment for indirect restorations

16
 OptiBond™ Versa
SECTION 3

OptiBond Versa: Core-

Technology Review

17
OptiBond™ Versa

OptiBond Versa Adhesive Technology

OH
O P OH Proven long-term bond efficacy

O GPDM
Monomer
O O

O O

Enhanced curing Tri- OptiBond Ternary

Superior enamel etching
efficiency, mechanical functional XTR Adhesive Solvent
capability and adhesion
integrity, and bond Monomer Technology System
compatibility

Improved mechanical
strength, bond strength and
Filled bond durability
Adhesive
18
 OptiBond™ Versa
CORE TECHNOLOGY REVIEW

Core OptiBond Technology – GPDM Monomer

Chemical Bonding

 Dual-action monomer
 Chemical and mechanical
OH Ionic
O P OH
bonding
O  20+ years of proven clinical
O O
success
O O

Covalent

19
 OptiBond™ Versa
CORE TECHNOLOGY REVIEW

Ternary Solvent System (TSS) – A Smart Solution

ETCHING PENETRATION &

EFFICACY SEALING
Acetone evaporates, Hydrophilic nature/enhanced
concentrating GPDM/water wetting of primer allows for
and increasing acidity and enhanced penetration into
thus etching dentin

Promotes increased etching Promotes effective wetting,

and enhanced bonding of penetration, priming and
enamel sealing of dentin

20
 OptiBond™ Versa
CORE TECHNOLOGY REVIEW

OptiBond Versa – Advanced Adhesive Technology

0.4 micron Barium glass filler and
nano-silica filler for reinforcing the
adhesive layer

A tri-functional monomer provides

enhanced cross-linking density,
improved curing, and enhanced
mechanical strength

Neutral pH of cured adhesive

provides universal bond compatibility
with all self-/dual-cured
cements/composites

Low Film Thickness: 5µ

21
 OptiBond™ Versa
SECTION 4

OptiBond Versa: Solving Bonding

Agent Limitations

22 22
 OptiBond™ Versa
SOLVING BONDING AGENT Limitation 1

Reduced Enamel Etch and Adhesive of Self-Etch

OptiBond
OptiBond FL
FL == 41MPa
41MPa (Total-Etch)
(Total-Etch) OptiBond
OptiBond Versa
Versa (Versa)
(Versa) == 40MPa
40MPa

ClearFil
ClearFil SE
SE Bond
Bond == 33MPa
33MPa Xeno
Xeno IV=
IV= 18MPa
18MPa

Swift E, et al, J Esthet Restor Dent. 2011 Dec;23(6):390-6. doi: 10.1111/j.1708-8240.2011.00465.x. Epub 2011 Oct 17.
23
 OptiBond™ Versa
SOLVING BONDING AGENT Limitation 2

Bond Incompatibilities of 1-Bottle Systems

OptiBond Versa Comparative Dentin Bond Strengths with Resin Cements
in Self-Cure Mode vs. 5th and 7th Generation Adhesives
35

30
Shear Bond Strength (Map)

25

20

15

10

0
G-Bond iBond Clearfil S3 Bond OptiBond XTR Prime & Bond NT Excite

Calibra Variolink II
*Indirect Dentin Bond Strength of 5 & 7th Gen Adhesives (with Self-Cured Calibra, Variolink, and NX3 Resin Cement).
th

All bonding agents were light-cured. Cements were allowed to self-cure. Kerr internal data.

Kerr Internal data

24
 OptiBond™ Versa
SOLVING BONDING AGENT Limitation 3

Post-Operative Sensitivity of Total-Etch

SEM images magnified at 2,000X and 10,000X

Qian E, et al. J Dent Res 90(Spec Iss A):1101, 2011 (www.dentalresearch.org).

25
 OptiBond™ Versa
SOLVING BONDING AGENT Limitation 4

Excessive Film Thickness of Adhesive Layer

~5μm ~35μm

SEM images magnified at 2,000X SEM images magnified at 2,000X

OptiBond Versa ClearFil SE

Qian E, et al. J Dent Res 90(Spec Iss A):1101, 2011 (www.dentalresearch.org).

26
 OptiBond™ Versa
SECTION 5

OptiBond Versa: The Six Pillars of

Bonding

27 27
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Where Are We Now

Universal
With Bonding?

A Different
Bonding Selective-
System Per Etch

?
Indication

Back to Old
8th
Bonding
Generation
Agent

28
 OptiBond™ Versa
THE PILLARS OF BONDING

Six Pillars for Clinical Success

What they “know”
BOND One data point, one point in time, one indication
STRENGTH

Will I get reproducible results?

CONSISTENT Do you have data to prove it?
How does it compare with other adhesives
COMPARATIVE on all substrates?
Do you have data to prove it?
Can it be used with all my current materials?
COMPATIBLE
Do you have data to prove it?
LONGEVITY Will it last and resist oral environment?
Do you have data to prove it?
INTEGRITY Can it withstand punishment and maintain a good marg
Do you have data to prove it?
Does it work in the mouth/will it cause pain?
IN-VIVO
EFFECTIVENESS Do you have data to prove it?
29
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Pillar 1: Consistent Adhesive

Performance

30 30
 OptiBond™ Versa
CONSISTENT ADHESION PERFORMANCE

OptiBond Versa – Consistent Adhesive Performance

She ar B ond Stre ngth, M ap

3rd Party Testing At 5 Independent Research Facilities

60 56.9

50 47.4
45.1 44
40.4 39
40 38.7 38.7
34.1 33.1

30

20

10

0
SUNY UNC Dental Advisor CR Reality

Dentin Enamel

31
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Pillar 2:
Comparative Adhesion Performance
on Different Substrates

32 32
 OptiBond™ Versa
COMPARATIVE ADHESION PERFORMANCE

OptiBond Versa – Comparative Direct Adhesive Performance

S h e a r B o n d S t r e n g t h (M a p )

60 56.9

50
49.5
‡
‡
40 38.7 ‡
‡
‡
30

20
35 36.4
27.0 24.5 25.8
10

0
OptiBond Versa OptiBond FL Xeno IV ClearFil SE Bond

Dentin Enamel

*Shear bond strength values obtained for samples bonded to human dentin and cut human enamel.
Tags above the group indicate no significant differences found between groups

33
Campillo-Funollet M, Munoz, C. J Dent Res 90(Spec Iss A):2463, 2011 (www.dentalresearch.org).
 OptiBond™ Versa
COMPARATIVE ADHESION PERFORMANCE

OptiBond Versa – Excellent Comparative Self-Etch Adhesive

Performance on Enamel
B o n d S tr e n g th , M P a

Enamel Bond Strength Evaluation at CR

40 Versa: 75%
35 Improvement Versa: 133%
35 Improvement
30

25
20 20
20
15
15

10

0
OptiBond Versa ScotchBond Universal All-Bond Universal Brush & Bond

Study conducted by CR. Published in CR August 2012

34
 OptiBond™ Versa
COMPARATIVE ADHESION PERFORMANCE

OptiBond Versa – Comparative Indirect Adhesive Performance

S h e a r B o n d S tre n g th , M P a

Dentin Bond Strength of Various Using NX3, Calibra, or Variolink Resin

Cements

45 43.1
39.6
NX3
40 Calibra
35.5
Variolink II
35 32.9
30 31.2 30.4
30 26.8

25
20
19
13.8 14.7
15
7.8 7.7 9.6
10
3.3 5.1
5 1.6 2.8
0
OptiBond Versa ClearFil S3 iBond Adper Easy Bond Excite Prime & Bond NT

35
dy conducted by Dr. Carlos Munoz, State University of New York, Buffalo
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Pillar 3: Compatibility

36 36
 OptiBond™ Versa
BOND COMPATABILITY

Excellent Bond Compatibility

with All Self-cured Resin Cements
Indirect Dentin Bond Strength of OptiBond XTR
OptiBond Versa
Used with Various Self-Cured Resin Cements
45
41.7
40
Shear Bond Strength, MPa

35
29.7 29.9 29.7
30
23.9
25
20
15
10
5
0
Calibra Variolink II RelyX ARC Panavia F2.0 NX3

*OptiBond Versa was light-cured and all resin cements were self-cured.

Study conducted by Kerr R&D

37
 OptiBond™ Versa
BOND COMPATABILITY
60.0
Recommended XTR
51.2 50.3
Mean Bond Strength (MPa) with
Manufacturer’s Recommended Bonding 43.9 43.8
Agent 45.0 41.8

33.9 (Bond 1) 33.9 34.5

32.5
28.8
28.8 (Excite F DC) 30.0
23.0
34.5 (Adper Easy Bond)
32.5 (OptiBond Solo Plus) 15.0
23.0 (Gradia Core Self Etching Bond)
29.5 (ClearFil SE Protect)
0.0
40.8 (ParaBond) Bond 1 Excite F DSC Easy Bond OptiBond SP Gradia Core SE
19.6 (Cosmedent Complete)
29.8 (One-Step Plus)
15.5 (Oxford Bond TE)
23.7 (Max Bond)
29.8 (Futurebond DC)
31.0 (Prelude)
20.4 (Brush & Bond)
35.5 (Prime & Bond NT)
16.1 (Adhere)
12.0 (Luxacore)
10.8 (Tenure Adhesive)
12.3 (Integra Bond)
23.9 (Clearfil DC Bond)
None Recommended
8.0 (Ketac Conditioner)
18.0 (Cavity Conditioner)

38
Study conducted by CR. Published January 2011
 OptiBond™ Versa
BOND COMPATABILITY

Excellent Comparative Indirect Adhesive Strength

to Dentin in Total Dark-Cure Mode
In d i r e c t B o n d S t r e n g t h ( M P a )

Comparative Adhesive Strengths in Total Dark-Cure Mode

35.0

30.0 29
26.6
25.0

20.0

15.0

10.0

5.0

0.0
OptiBond XTR/NX3 Multilink® Primers A&B/Multilink®
Automix

*All systems were evaluated when used in total dark cure mode (no light used)
Study conducted by Dr. Carlos Munoz, State University of New York, Buffalo.
39
 OptiBond™ Versa
SUBSTRATE COMPATIBILITY

OptiBond Versa Bonds to Porcelain without a Silane Primer

NX3/Versa ADHESIVE

*All systems were evaluated when used in total dark cure mode. All substrates were etched with HF. .

Kerr R&D Data. 40

OptiBond
NX3 Versa™ Versa

OptiBond Versa Bonds Effectively to Ceramics

Chemical Bonding (GPDM Monomer)

O O

Chemical Bonding (GPDM Monomer )

O P OH O P OH

O O
H H
H H
O O

S S O

Li+ - O
Micromechanical P O

OH
XTR Adhesive

e.max surface

Li+ - O P O

OH

HF Etched e.max surface

Three complimentary bonding mechanisms result in a strong & durable bond without silane.

41
 OptiBond™ Versa
BOND COMPATABILITY

OptiBond Versa with NX3: Effective bonding to all restorative substrates

in Total-Dark Cure Mode

Superior Indirect Bond Strength of NX3 & OptiBond Versa vs.2 Other
Cementation Systems in Total Dark-Cure Mode

*No Silane primer or metal primer is used for NX3/OptiBond XTR (OptiBond Versa)
42
Study conducted by Kerr
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Pillar 4 & 5:
Longevity & Integrity

43 43
 OptiBond™ Versa
LONGEVITY

Exceptional Long-Term Bonding Performance

B o n d S t r e n g t h R e t e n ti o n R a t e ( % )

Micro-Tensile Bond Strength Retention Rate of Self-Etch

Adhesives
After 12-Month Storage in Artificial Saliva at 37C

90.0%
84.5%
80.0% 75.9%
71.9%
70.0%

60.0%
52.1%
50.0%

40.0%

30.0%

20.0%

10.0%

0.0%
OptiBond Versa ClearFil SE Bond Adper Easy Bond Bond Force

44
Lorenzo Breschi, DDS, PhD, University of Trieste, Trieste, Italy
 OptiBond™ Versa
INTEGRITY

OptiBond Versa Provides Outstanding Marginal Integrity

% Continuous Margin in Class I Restorations after
Thermocycling and Mechanical-Cycling
OptiBond FL

Clear SE Bond

OptiBond XTR

OptiBond All-In-One

G-Bond

Easy Bond

S3 Bond

Xeno V

iBond SE

Prompt L-Pop

Continuous Margin AdhesSE One

0 10 20 30 40 50 60 70 80 90 100
Marginal integrity studies
by SEM microscopy % Continuous Margin

Uwe Blunck, DDS, PhD, Charité-Universitätsmedizin Berlin, Berlin, Germany

45
 OptiBond™ Versa
THE 6 PILLARS OF BONDING

Pillar 6:
In-Vivo Efficacy

46
 OptiBond™ Versa
IN-VIVO EFFICACY

Class V Restorations

• Cervical lesions
• Shallow/Flexible
• Exposed roots
• Acid contact to tissues

One of the most difficult restorative cases

for a self-etch bonding agent

Dr. B. Van Meerbeek, Catholic University

47
 OptiBond™ Versa
IN-VIVO EFFICACY

OptiBond Versa 12-Month Clinical Performance

in Class V Carious/Non-Carious Lesions

Overall Clinical Evaluation in Class V Restorations

98% 98% 100%98%
100%
95%
89% 90%
% Cases

90% 86%
80%

70%

60%

50%

40%
Marginal Integrity No marginal staining No or minimal sensitivity Patient Satisfaction
OptiBond XTR OptiBond FL

48
r. B. Van Meerbeek, Catholic University (BIOMAT)
 OptiBond™ Versa
IN-VIVO EFFICACY

OptiBond Versa 12-Month Clinical Performance

in Class V Carious/Non-Carious Lesions – Marginal Integrity

Marginal Integrity Class V Restorations

100% 100% 98% 97% 99% 97% 98%
100%
95%
89%
% Cases

90%
85%
80%
75%
70%
65%
60%
55%
50%
Baseline 3-mo 6-mo 12-mo
OptiBond XTR OptiBond FL

Clinically accepted marginal integrity = harmonious margins and/or <150µ gap

49
r. B. Van Meerbeek, Catholic University (BIOMAT)
 OptiBond™ Versa
SECTION 6

Conclusion

50
 OptiBond™ Versa
SIMPLIFIED INVENTORIES & PROCEDURES

OptiBond Versa Simplifies Dental Bonding Inventories

and Procedures

DIRECT INDIRECT

Ceramic Veneers Porcelain/Composite Metal or PFM Crown

No Separate Phosphoric Acid Etchant

No Separate Dual-Cure Activator
No Desensitizer
No Separate Silane Primer
No Separate Metal Primer 51
OptiBond™ Versa

UniversalAll Direct/Indirect Indications

All Substrates, All Composites/cements,

No Separate Phosphoric Acid Etchant, Dual-cure Activator, Desensitizer,

Simplified
Ceramic Primer or Metal Primer

Consistent Effective
& High Performance

A True “Simplified Universal Self-Etch Adhesive System” That

Can Be The Foundation for All Restorations

Ranked #1 by REALITY among all self-etch adhesives

52
OptiBond™ Versa

True Value of OptiBond Versa

53
53
 OptiBond™ Versa
SIMPLIFIED INVENTORIES & PROCEDURES

OptiBond Versa – A New Paradigm

for Dental Bonding

 Solves the Limitations

of bonding agents
 Fulfills all Pillars of Bonding
 Simplifies bonding
techniques
 Consolidates inventories

54
OptiBond
NX3 Versa™ Versa

NX3 VERSA for

Cementation System
“Because the Last 3 Minutes of an Aesthetic
Restoration Should be the Easiest,
Not the Hardest”

55
OptiBond
NX3 Versa™ Versa

The Last 3 Minutes . . .

In-Office CADCAM

Reduction Scanning Milling Firing Final Cementation

Up to 2 Weeks

Final Cementation

Reduction
Traditional Lab

56
OptiBond
NX3 Versa™ Versa

Pain Points Stemming from the Last 3 Minutes

Challenging Cleanup Color shift/marginal staining

Bond Incompatibilities/Efficacy Post-Op Sensitivity

These are shortcomings of cementation systems.

57
OptiBond
NX3 Versa™ Versa

Shortcomings of Dual-Cure Bonded

Resin Cement Systems

Clean-up Color Stability Bond Incompatibility Post-Op Sensitivity

& Efficacy
Bonded X X X X
Resin
Cement

Most cementation systems (bonded resin cements) share one or more of

these shortcomings.
58
OptiBond
NX3 Versa™ Versa

Why does poor cleanup happen?

Material Instability

Generates Free
+ Radicals & Initiates
Polymerization

Tertiary Amine BPO

• Unstable
• Performance Variabilities

BPO contained in catalyst paste of dual-cure cements can be unstable and will
cause variance in gel-set times.
59
OptiBond
NX3 Versa™ Versa

Nexus Technology: Increased Stability of Initiator

System

H S H R2
N C N Generates Free
R1 + R1 C O O H Radicals & Initiates
Polymerization
N R3
PTU Derivative Tertiary Hydroperoxide (t-HPO)

NX3 dual-cure tertiary hydroperoxide increases stability to provide stable gel-set times
and excellent shelf-life--no refrigeration required.
60
OptiBond
NX3 Versa™ Versa

Nexus Technology: Material stability

Enhances Cleanup
Set Time Before and After Aging
(Aging Condition: 42C for 8 Weeks)

20 Before Aging After Aging

Set time, Minutes

15

10

0
NX3 Nexus 2 RelyX ARC Calibra Variolink II

NX3 non-BPO formulations results in, predictable set times and performance. Nexus
Technology provides consistent gel-set time for effortless cement removal.
61
OptiBond
NX3 Versa™ Versa

What causes color shift?

Redox process causes color instability

Generates Free
+ Radicals & Initiates
Polymerization

Tertiary Amine BPO

• Unstable BPO color shift

• REDOX reaction discolors tertiary amine

BPO contained in catalyst paste of dual-cure cements can be unstable and color shift
inside the syringe. Tertiary-amine base react with catalyst to cause further color
instability after curing. 62
OptiBond
NX3 Versa™ Versa

Nexus Technology: Tertiary-amine and BPO free

self-cure initiator system

S
H H R2
N C N Generates Free
R1 + R1 C O O H Radicals & Initiates
Polymerization
N R3

PTU Derivative Tertiary Hydroperoxide (t-HPO)

NX3 dual-cure self-cure initiator system does not contain tertiary amines or BPO.
Results in higher color stability in the syringe and after curing.
63
OptiBond
NX3 Versa™ Versa

Enhance Color Stability NX3 Catalyst Paste

NX3 Nexus2 RelyX ARC Calibra Variolink II

Before
Aging

After Aging

Study conducted by Kerr. Uncured catalyst pastes were aged for 8 weeks at 37◦ C

Non-BPO initiator system of NX3 greatly minimizes discoloration of

uncured catalyst paste
64
OptiBond
NX3 Versa™ Versa

Color Stability Comparison of Cured Cement

NX3 DC Multilink
Clear Transparent

Initial

Aging

28 wks 12 wks
In 37◦ C water In 37◦ C water
Study conducted by Kerr

Nexus tertiary-amine & BPO free formulation provide reliable color stability
to enhance aesthetics.
65
OptiBond
NX3 Versa™ Versa

Quantitative Color Stability Evaluation of NX3

Total Color Change (E) in Dual-Cure Mode

10.00
NX3
9.00
Calibra
8.00
Rely X
7.00 ARC
6.00 Multilink
5.00
4.00
3.00
2.00
1.00
0.00
0 20 40 60 80 100 120 140 160 180 200
Days
T. Hilton et al, IADR 2010 Abst 2246, “A Comparison of Resin Cement Color
Stability Over 6 Months”, Oregon Health & Science University.

Quantitative analysis demonstrates minimal color shift with NX3 dual-cure cement.
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OptiBond™ Versa

What causes low bond incompatibility & adhesive performance?

Un-optimized formulations

Self-Cured Resin Cement/Core Material

• PFM /PFZ
Tertiary • Metal Crowns
Amine (Base) • Opaque Restorations
• Bulk-Fill Composite Core Material

Acid/Base Reaction + Phase Separation

Single Bottle Adhesive System

Acidic • 5th Generation Total-Etch Adhesive
Adhesive
• 7th Generation Self-Etch Adhesive

Direct bonding agents thus require activators for use with self-and dual-cure
cements or use of another bonding system. 67
OptiBond
NX3 Versa™ Versa

Bond Strengths with Self-Cure Resin Cements

I n d ir e c t B o n d S t r e n g t h ( M P a )
Bond Compatibility of Self-Cure Resin Materials

25
22.4
20

15

10
5.7
5

0
OptiBond XTR + self-cure resin material Scotchbond Universal* + self-cure resin material

Study conducted by Reality, Inc. 2012

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OptiBond
NX3 Versa™ Versa

NX3 XTR Bond Compatibility

S h e a r B o n d S tre n g th , M P a

Dentin Bond Strength of Various

Using NX3, Calibra, or Variolink Resin Cements

45 43.1
39.6 NX3
40
35.5 Calibra
35 32.9
30 31.2 30.4
30 26.8
25
20 19
13.8 14.7
15
7.8 7.7 9.6
10
3.3 5.1
5 1.6 2.8
0
OptiBond ClearFil S3 iBond Adper Easy Excite Prime &
XTR Bond Bond NT
Study conducted by Dr. Carlos Munoz, State University of New York, Buffalo

NX3 XTR high level of bond compatibility together and with competitive
materials to enhance performance
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 OptiBond
NX3 Versa™ Versa

Excellent Comparative Indirect Adhesive Strength

to Dentin in Total Dark-Cure Mode
I n d ir e c t B o n d S tr e n g th (M P a )

Comparative Adhesive Strengths in Total Dark-Cure Mode

35.0

30.0 29
26.6
25.0

20.0

15.0

10.0

5.0

0.0
OptiBond XTR/NX3 Multilink® Primers A&B/Multilink®
Aut...

*All systems were evaluated when used in total dark cure mode (no light used)

Study conducted by Dr. Carlos Munoz, State University of New York, Buffalo.
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OptiBond
NX3 Versa™ Versa

How can you minimize sensitivity?

Good dentinal and marginal sealing

• Effective enamel etch • Effective dentin penetration and sealing

• High bond strengths to enamel • Very low reported sensitivity
• Outstanding marginal integrity • Comfortable post-op experience

Strong enamel bonds and penetration through dentin minimize

post-operative sensitivity.
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OptiBond
NX3 Versa™ Versa

OptiBond XTR: Enamel Etch and Adhesion

Effectiveness

OptiBond
OptiBond XTR
XTR (XTR)
(XTR) ==
OptiBond
OptiBond FL
FL == 41MPa
41MPa 40MPa
40MPa

ClearFil
ClearFil SE
SE Bond
Bond == 33MPa
33MPa Xeno
Xeno IV=
IV= 18MPa
18MPa

Study conducted by Swift, et al, J Esthet Restor Dent. 2011 Dec; 23 (6): 390-6. doi:10.1111/j.1708-8240.2011.00465.x.Epub 2011 Oct
17

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 OptiBond
NX3 Versa™ Versa

OptiBond XTR: Enamel Effectiveness

Study conducted by CR. Published 8/12/12

73
OptiBond
NX3 Versa™ Versa

OptiBond XTR: Effective Bonding to all

Restorative Substrates

Study conducted by CR. Published 8/12/12

Strong adhesion without silane or metal primers.

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OptiBond
NX3 Versa™ Versa

OptiBond XTR with NX3: Effective Bonding to all

Restorative Substrates in Total-Dark Cure Mode
Superior Indirect Bond Strength of NX3 & OptiBond XTR vs.
2 Other Cementation Systems in Total Dark-Cure Mode

Study conducted by Kerr

Excellent compatibility of XTR with NX3 shows highest level of adhesion

effectiveness without silane, separate metal primers, or activators.
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 OptiBond
NX3 Versa™ Versa

OptiBond XTR with NX3: Effective Bonding to Lava™

Ultimate Blocks
In d ire c t B o n d S tre n g th (M P a )
Comparative Indirect Bond Strength of NX3 & OptiBond XTR vs.
Scotchbond Universal in Total Dark-Cure Mode with Lave Ultimate

40
35.3
35
30
25.5
25
20
15
10
5
0
NX3/... RelyX Ultimate/Scotchbond
Uni...

Study conducted by Kerr

NX3 XTR has excellent adhesion to Lava™ Ultimate blocks in total dark-cure mode
without activators or other ancillary products.
76
OptiBond
NX3 Versa™ Versa

NX3 Versa - 6 & 7 Lingual 1.5 year follow-up

Cases provided by Dr. Darin O’Bryan

77
OptiBond
NX3 Versa™ Versa

NX3 Versa – No marginal staining

Cases provided by Dr. Darin O’Bryan

78
 OptiBond
NX3 Versa™ Versa

OptiBond Versa 18-month follow up

Composite mock-up Immediate post-op Immediate post-op

Cases provided by Dr. Darin O’Bryan

18-months post-op 18-months post-op

79
OptiBond
NX3 Versa™ Versa

80
OptiBond
NX3 Versa™ Versa

CEREC Doctor feedback to NX3/Versa (XTR)

81
81
OptiBond
NX3 Versa™ Versa

NX3 and OptiBond Versa-Better Together

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OptiBond
NX3 Versa™ Versa

83
OptiBond
NX3 Versa™ Versa

NX3: High Radiopacity

R a d io p a c it y , % A lu m in u m
Radiopacity of NX3 vs. RelyX Ultimate

350 333
300
250
200 167
150
100
50
0
NX3 RelyX Ulti...

NX3 radiopacity allows for clear review under radiograph.

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OptiBond™ Versa

COMPETITOR PRODUCT

HERAEUS KULZER:
3M Espe
Dentsply

85