Differential diagnosis of mechanical

hemolytic and hepatic jaundice

Beni Kelner
Group S1711
Mechanical hemolytic 

 Mechanical hemolytic anemia is a form of hemolytic anemia due

to mechanically induced damage to red blood cells. Red blood cells, while
flexible, may in some circumstances succumb to physical shear and
compression. This may result in hemoglobinuria.

Is a non-immune mediated destruction of red blood cells that can be associated

with blood transfusion. Various etiologies include the use of blood warmers,
small bore needles or high infusion rates.
Hepatic jaundice

 Synonym – intrahepatic or hepatocellular

jaundice
Hepatitis, cirrhosis, cancer of the liver.
bilirubin uptake, conjugation, excretion
Blood - unconjugated bilirubin , conjugated
bilirubin
Urine – urobilin normal or , bilirubin
Faeces – stercobiline normal or
Differential diagnosis Jaundice