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    Metabolic syndrome is a set of risk factors that includes abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. It is caused by insulin resistance associated with obesity. Risk factors include family history, lifestyle factors like poor diet and lack of exercise, tobacco use, and increasing age. Metabolic syndrome affects 20-25% of people worldwide and 13.3% of people in Indonesia. Clinical manifestations include chest pain, shortness of breath indicating cardiovascular complications, as well as acanthosis nigricans and neuropathy in patients with insulin resistance or diabetes. Complications include numerous cardiovascular issues and increased risk of cancers, stroke, and other conditions.

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    METABOLIC SYNDROME

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    METABOLIC SYNDROME

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    Metabolic syndrome is a set of risk factors that includes abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. It is caused by insulin resistance associated with obesity. Risk factors include family history, lifestyle factors like poor diet and lack of exercise, tobacco use, and increasing age. Metabolic syndrome affects 20-25% of people worldwide and 13.3% of people in Indonesia. Clinical manifestations include chest pain, shortness of breath indicating cardiovascular complications, as well as acanthosis nigricans and neuropathy in patients with insulin resistance or diabetes. Complications include numerous cardiovascular issues and increased risk of cancers, stroke, and other conditions.

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    44 views11 pages

    Metabolic Syndrome

    Uploaded by

    hafshah
    Metabolic syndrome is a set of risk factors that includes abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. It is caused by insulin resistance associated with obesity. Risk factors include family history, lifestyle factors like poor diet and lack of exercise, tobacco use, and increasing age. Metabolic syndrome affects 20-25% of people worldwide and 13.3% of people in Indonesia. Clinical manifestations include chest pain, shortness of breath indicating cardiovascular complications, as well as acanthosis nigricans and neuropathy in patients with insulin resistance or diabetes. Complications include numerous cardiovascular issues and increased risk of cancers, stroke, and other conditions.

    Copyright:

    © All Rights Reserved
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    of 11

    METABOLIC

    SYNDROME
    Venita O.Tambunan
    1610211092
    DEFINISI
     Metabolic syndrome (MS) is a set of risk factors for Type-2
    diabetes mellitus (T2DM) and cardiovascular disease (CVD),
    which includes several syndrome :
     Abdominal obesity
     Hyperglycemia

     Dyslipidemia

     Hypertension
    Etiology
     Insulin resistance associated to obesity is considered the fundamental cause of
    metabolic syndrome
     Risk factors include :
     family history
     Bad lifestyle (poor diet,inadequate exercise)
     tobacco use,increased cardiovascular complications
     risk increases as you get older
     Asian and African-Carribean people may be at greater risk
     other conditions – your risk is greater if you've had cardiovascular
    disease, polycystic ovary syndrome (PCOS)
     Resistensi insulin didefinisikan sebagai suatu kondisi produksi insulin normal ,
    tetapi terjadi  sensitivitas jaringan terhadap kerja insulin, sehingga terjadi 
    sekresi insulin sebagai bentuk kompensasi sel Beta.
    Epidemiologi
     SM Di dunia adalah 20-25 %
     SM di Indonesia 13,3% (Tahun 2007)
     Penelitian di Depok (2001) menggunakan kriteria National
    Cholesterol Education Program Adult Treatment Panel III
    (NCEP-ATP III) dengan modifikasi Asia menunjukkan
    prevalensi sindrom metabolik pada pria 25.7% dan 25%
    wanita
    Kriteria Sindrom Metabolik
    CLINICAL MANIFESTATION
     Chest pain or  Xanthelasmas: In
    shortness of breath: patients with severe
    Suggesting the rise of dyslipidemia
    cardiovascular
    complication
     Acanthosis nigricans,
    hirsutism, peripheral
    neuropathy, and
    retinopathy: In
    patients with insulin
    resistance and
    hyperglycemia or
    with diabetes mellitus
    Prognosis
    The complications of metabolic  Metabolic syndrome may also be
    syndrome are broad : linked to neuropathy beyond
     Numerous associated cardiovascular hyperglycemic mechanisms through
    complications exist, particularly inflammatory mediators.
    coronary heart disease, but also atrial
    fibrillation,heart failure, aortic
    stenosis,ischemic
    stroke,thromboembolic disease.
     Each of the components of metabolic
    syndrome has been associated with
    elevated stroke risk
    Prognosis
     Breast cancer has also been linked  according to a retrospective cohort
    to metabolic syndrome, possibly study,metabolic syndrome
    through dysregulation of the between pregnancies increases the
    plasminogen activator inhibitor-1 risk of recurrent preeclampsia
    (PAI-1) cycle.  Metabolic syndrome has been
     Additional studies have linked blamed for accelerated cognitive
    metabolic syndrome with cancers aging.
    of the colon, gallbladder, kidney,
    and possibly, prostate gland
    Terimakasih 

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