POTENSI UMBI LOKAL

SEBAGAI
IMUNOMODULATOR
Ika Puspitasari, MSi,PhD, Apt
Dept. Farmakologi & Farmasi Klinik, Fakultas Farmasi UGM
PPRA RSUP dr. Sardjito
ika.puspitasari@gmail.com; ika_tunggul@ugm.ac.id
COVID-19

•Self limiting disease

•Precautions---IPC
•Immune system
•Bagaimana meningkatkan imun system?
IPC Infection Prevention Control
SWAMEDIKASI YANG DILARANG UNTUK
COVID-19: CHQ, azitromisin, oseltamivir (PDP ringan )
How to boost your immune system
• Don't smoke.
• Eat a diet high in fruits and vegetables.
• Exercise regularly.
• Maintain a healthy weight.
• Get adequate sleep.
• Take steps to avoid infection, such as washing your hands
frequently and cooking meats thoroughly.
• Try to minimize stress.
Fact
• About 100 trillion bacteria reside in the gut and they produce
metabolites that have health effects
• 70-80% of the body’s immune cells are concentrated in the gut
• There are 100 million neurons located along the gut which
produce various neurotransmitters that regulate mood and
satiety
• 95% of the body’s total serotonin is located in the gut
• External stimuli, such as nutrition and environment, can have a
strong influence on the development of the GI system
Dysbiosis
• An imbalance in gut microbiota (‘dysbiosis’) during infancy
can have a negative impact on health and wellbeing, and has
been linked to an increase in asthma and allergy, as well as
infantile colic and GI disorders.6,7 
• It has also thought to increase the risk of obesity and
metabolic disorders later in life
No Bahan pangan Hasil penelitian
1. Porang Menurunkan jumlah bakteri E.coli, meningkatkan
jumlah asam lemak rantai pendek, menurunkan pH
feses

2. Uwi, gadung, talas Indek glisemik 14-22, peningkatan jumlah bakteri L.

acidophilus, L. paracasei, L. rhamnosus, dan L.
plantarum,

3. Ganyong dan garut Peningkatan jumlah Lactobacillus

4. Ubi jalar Peningkatan Bifidobacterium dan Lactobacillus, terjadi
penurunan jumlah Enterobacillus, Clostridium
perfringens dan Bacteroides
Stay healthy, stay happy, stay home