CLASSIFICATION:

 Chemotherapy of Nematodes :
Ivermectin Mebendaz
ole
Albendazole
Piperazine
Tetramisole
Diethyl carbamazine
citrate Pyrantel palmoate
Thiabendazole
 Chemotherapy of Trematodes :
Praziquantel


Chemotherapy of Cestodes :
Niclosamide
NEMATODES:

 Nematodes are elongated

round worms.
 It possess a complete
digestive system i.e, from
mouth to anus.
 These nematodes can cause
infections of intestine, blood
& tissues.
 DRUGS USED FOR THE TREATMENT
NEMATODES
OF
:
MEBENDAZOLE:

 Pin worm (Enterobius

 Hook vermicularis) (Nectar
worm
 Round wormamericanus)
(Ascariasis
lumbricoides)
 Whip worm (Trichuris trichuria)
MECHANISM OF ACTION:
 Interfere with microtubules
synthesis will leads to stop
the mitosis & also decreases
the glucose uptake.
 Affected parasites are expelled

out from the faeces.

ADVERSE
EFFECTS:
 Diahorrea.
 Abdominal pain.

CONTRA INDICATIONS:
 In pregnant woman, because it

shown to be embryotoxic &

teratogenic in experimental animals.