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Mental Disorders in Elderly

Indah Sandy Febryanti


030.05.113
who are they?
 WHO (1989)
>60 years old

 Indonesian Health Ministry


60 – 69 years old

 Greater improvement on health care


elder population >>
Greater life expectancy

 Indonesia Today : 24 millions elder (9,77%)

 World Estimation : 2030 - 70 millions


2050 - 82 millions
aging process
old age is not a disease.
Lifestyle
Diet & Nutrition
degrading/degenerating
Environment
physiological organ functions
etc.

sociological psychological Integrity


versus
new role
Despair
in society
(Erik Erikson)
psychiatric examination
of the older patient

Physical Examination

Laboratory Examination


Psychiatric History


Mental State Examination


Neuropsychological Evaluation
physical & laboratory
Complete physical examination
Supportive laboratory exams
(kidney function, liver function, ct-scan, etc)

 Due to aging process


 Diagnostics
 Exclude overlying diseases
 Psychiatry manifestation as side effect of general condition or
medication
 Precaution before giving prescription
psychiatric history
 Minor memory impairments
benign senescent of forgetfulness

 Childhood and adolescent history


personality, defense mechanism, coping strategies

 Occupational history (pension)


 Plans for future?

 Current social situation


children, financial, caregiver

 Marital history
spouse, widow, grief
Mental State
 General Description Examination
 Functional Assessment -- Activity Daily Living

 Mood, Feelings and Affect


mood disturbances : early sign of dementia

 Perceptual Disturbances (Hallucinations, Illusions)

 Language Output (Aphasia)

 Visuospatial Functioning Decline in this function is normal w/ aging

 Thought (Loss ability of abstract thinking – early sign of dementia)

 Sensorium and Cognition

 Judgment
Neuropsychological
Evaluation
Mini Mental State Examination (MMSE)

Cognitive functions : orientation, attention, calculation, recall, etc


Wechsler Adult Intelligence Scale-Revised (WAIS –R)

Assessment of intellectual abilities. Verbal, performance, IQ scores

Bender Gestalt Test / Halstead Reitan Battery


Visuospatial functions.

Geriatric Depression Scale


To assess depression
epidemiology
 Estimation on mid 20th century
Psychiatric Disorders : 20 millions.

 Indonesian National Prevalence


Mental disorder at age > 15 yrs old 11,6%
Psychotic disorder 4,6 %

Highest prevalence : DKI Jakarta (20,3‰)


Nangroe Aceh Darussalam (18,5‰),
West Sumatera (16,7‰),

 Mental disorder prevalence increases as the age.


>75 yrs old : 33,7 %

Other risk factors : Female, low education level, unemployed, and poverty.
Sleep
Sleep
Disor deme
deme
Disor
der
der ntia
ntia

Bipo
Bipo depre
lar depre
lar II ssive
ssive

MENTAL Soma
Soma
tofor
tofor
schizo-
schizo-
-
-
DISORDER
m
m phrenia
phrenia

OF Anx
OLD
Anx delus
delus
AGE
iety
iety ional
ional
Dementia
 A generally progressive and irreversible impairment of the
intellect.

 Develops over time. Gradually.

 Characteristic Changes
cognition, memory, language, visuospatial functions

behavioral disturbances :
agitation, restlessness, wandering, rage, violence, shouting, social
disinhibiton, sleep disturbances, delusions.
 Causes of Cognitive Impairment
Brain injuries, cerebral tumors, AIDS, alcohol, medications, infections,
chronic pulmonary disease, inflammatory.

 10-15% have potentially treatable Conditions.


systemic disorder (heart disease, renal disease, endocrine, etc)
primary mental disorders (mostly depressive)
ALZHEIMER DEMENTIA
50 -60 %
female > male

 Memory impairment with at least one of the following : aphasia, apraksia, agnosia, executive
function impairment.

 Etiology unknown.
Hypothetically : loss of selective colinergic neurons.
Loss of volume in frontal and temporal lobe.

 Prevention, not useful


 Palliative Care
 To decrease agitation and agression : propanolol, pindolol, buspirone, valproate.
Haloperidol for acute behavioral disorder.

VASCULAR DEMENTIA
Cognitive deficit (as Alzheimer)
but associated with focal neurological signs

Sudden onset.

Prevention useful.
 Diagnostic MRI  Decreased cerebral blood flow causes dementia.
Depressive Disorders
 15 %

 Symptoms and Signs


Reduced energy and concentration
Sleep problems
Decreased appetite, weight loss
Somatic complaints.

 Age itself is not a risk factor


But : widowed, chronic medical illness, etc

 Suicidal Ideation

 Pseudodementia
The dementia syndrome of depression
Bipolar Disorder
 1 % prevalence (all age category)

 Recurrence

 Symptoms and Signs


expansive mood, irritability, decreased sleeping hours,
impulsive, distracted easily.

 Deficit in consciousness, disorentation and cognitive


impairment  organic cause.

 Individualized dose of Lithium.


Neurotoxicity in Elderly >>
Schizophrenia
 First episode after age 65 : RARE
 20 % : no active symptoms by age 65
80 % : varying degrees of impairment

 Greater prevalence of paranoid schizophrenia in the late-


onset-type

 30 % Residual Type
emotional blunting, social withdrawal, eccentric behavior,
illogical thinking, delusions, hallucinations
Delusional Disorders
 Age of onset : 40 – 55 yrs old

 Delusions
Persecutory >>
Somatic

 Paraphrenia
late onset of delusional disorder
persecutory delusions
not associated with dementia

 Physical or Psychological stress.


death of spouse, medical illnesses, surgery, visual impairment, deafness
Anxiety Disorders
 Panic disorder, phobia, OCD, generalized anxiety disorder,
acute stress disorder, PTSD.

 The thought of death with a sense of despair may cause


anxiety

 Previous personality organization


Somatoform Disorder
 Somatic complaints in older age is very COMMON.

 Hypochondriasis
common in >60 yrs
peak incidence : 40 – 50 yrs

 Repeated physical examinations


Avoid invasive and high risk examinations.

Clinicians should acknowledge that the complaint is real.


Sleep Disorder
 Altered regulatory and physiological systems in aging.

 Causes
Primary sleep disorder
dysomnia >> (primary insomnia, restless legs syndrome, sleep apnea)
Mental disorder
General medical disorder
Social and environmental factors

 Interfering Conditions
Pain, nocturia, dyspnea, heartburn
Lack of daily structure and of social or vocational responsibilites

 REM Sleep : more and shorter REM episode, less total REM Sleep
NREM Sleep
Management
Psychopharmacological
 A pretreatment medical evaluation
 Bring all currently used medications
 GOALS
to improve quality of life
maintain persons in the community
delay or avoid placement in nursing home
 Psychotropic drugs
given in equally divided doses (3-4 times) over a 24-hour period.

 Response monitoring

 Individualization of Dosage
Drug metabolism (liver)
Drug clearance (kidney and liver)
Drug absorption (GI)
Drug distribution (fat body mass)

 The lowest possible dose should be used to achieve the desired


therapeutic response.

 Multiple drug interactions.


Psychotherapy
 Insight-oriented psychotherapy
supportive psychotherapy
cognitive therapy
group therapy
family therapy

 Adapting to common age-related issues


- recurrent and diverse losses (death of friends,etc)
- the need to assume new roles
- the need to accept mortality/death

 Psychotherapy
- increases self-esteem and self-confidence
- decreases feelings of helplessness and anger
- improves the quality of life
References
  
 Kaplan HI, Sadock BJ and Grebb JA. Kaplan-Sadock. Sinopsis Psikiatri. Jilid 1. Alih bahasa : Wijaya Kusuma.
Jakarta : Bina Rupa Aksara. 2010. Hal 867-891.
 Busse EW and Blazer DG. Textbook of Geriatry Psychology. Edisi kedua. Washington : The American Psychiatric
Press. 1997. Hal 155-263.
 Sadock BJ, Sadock VA. Concise Textbook of Clinical Psychiatry. Edisi kedua. Philadelphia : The William-Wilkins.
2004. Hal 599-602.
 Sadock BJ, Sadock VA. Synopsis of Psychiatry. Edisi kesepuluh. Philadelphia : The William-Wilkins. 2007. Hal
1348-1358.
 Kaplan HI, Sadock BJ and Grebb JA. Kaplan-Sadock Sinopsis Psikiatri jilid 1. Alih bahasa : Wijaya Kusuma.
Jakarta : Bina Rupa Aksara. 2010. Hal 116-134.
 WebMD. Alzheimer's Disease and Other Forms of Dementia. Diunduh dari :
http://www.webmd.com/alzheimers/guide/alzheimers-dementia. Diakses tanggal 10 Desember 2010.
 Alzheimer's Society. What is vascular dementia? Diunduh dari :
http://alzheimers.org.uk/site/scripts/documents_info.php?categoryID=200137&documentID=161&pageNumber=1.
Diakses tanggal 10 Desember 2010.
 Helpguide.org. Depression in Older Adults and Elderly. Diunduh dari :
http://helpguide.org/mental/depression_elderly. Diakses tanggal 12 Desember 2010.
 Laporan Riset Kesehatan Dasar Tahun 2007. Departemen Kesehatan RI.
 Covino, Jennifer. Depression in Geriatric Patients. Diunduh dari : http://www.medscape.com/viewarticle/520534.
Diakses tanggal 12 Desember 2010.
 Moran M, Lawlor B; Late-life Schizophrenia; PSYCHIATRY 4:11; 2005 The Medicine Publishing Company Ltd,
2005 (ebook).

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