Adequacy of blood

Prepared by
Saba Baber
 Guideline for choosing how much blood to transfuse
Hematocrit Of donor Red cells
50% 60% 75% 80%
Target increase in 1g/dl 4.2ml/kg 3.5ml/kg 2.8ml/k g 2.6ml/kg
hemoglobin level

2g/dl 8.4ml/kg 7.0ml/kg 5.6ml/kg 5.2ml/kg

3g/dl 12.6ml/kg 10.5ml/kg 8.4ml/kg 7.8ml/kg
4g/dl 16.8ml/kg 14.0ml/kg 11.2ml/kg 10.4ml/kg

.An example , to raise the hemoglobin level by 4g/dl in a patient weighing 40kg and
With a heamatocrit of 60% would require 560 ml .this calculation assumes a blood volume
of 70ml /kg. mean in this chart you just multiply the patient weight from your desire
increase hemoglobin , volume which shown in ml i.e. 14.0 x40=560ml ,
• if you increase 3g , Hematocrit 50% patient weight is 20kg so, 20x 12.6=252 for cross check
252/20=12.6ml/kg.
•If you increase 6 gram and hematocrit is 75% patient weight is 40kg check 1g increase at
75%=2.8ml/kg so 6x2.8=16.8 ml/kg then 16.8 x40=672ml is required volume of blood.
 Reference
• Guidelines for the Clinical Management of
Thalassaemia [Internet]. 2nd Revised edition.
• Show detailsCappellini MD, Cohen A,
Eleftheriou A, et al.
• Nicosia (CY): Thalassaemia
International Federation; 2008.
• Contents
 Calculation
Patient blood volume

= patient weight x surface area

=40kg x 70= 2800ml
Target increase hemoglobin (6grams)
= patient blood volume x target increase hb/ 100
=2800mlx6/100=168 grams
Donor Hb in blood unit
= volume of w/b drawn x Donor hb/100
=450 x14/100=63 %
Required blood volume
= pt target increase hb x packed cell volume/ packed cell hematocrit
= 168X 200/63 =533ml
 Comparison
• From chart if patient weight is 40kg Target increase 3grams
unit hematocrit 75%volume required= 40 x 8.4= 336ml

• From calculation:
• Patient blood volume= 40x70=2800ml
• Target increase hb= 2800ml x3/100= 84
• Packed cell volume=300ml
• Donor hematocrit=75%
• so/, 84 x 300/75 =336ml
Its proven from both mehod the result will same
THANK YOU