PRESENTED BY: Mir Zeeshan

ID NO: 18219
SUBMITTED TO: Dr. Abdul Rashad

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 PRESENTATION FLOW

Introduction
Epidemiology
Sub-types
Pathology
Medical treatment
Rehabilitation
Prognosis

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 Introduction

“It is an acquired ,frequently

severe ,monophasic
autoimmune illness of
Peripheral Nervous
System(PNS)”

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 Approximately 85% patients recover
spontaneously while 10% patients need
hospitalization

Its prevalence has been reported to vary from

region to region

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 Epidemiology
According to more recent study ,GBS occurs
throughout the world with a medium incidence of 1.3
cases per 100,000 population
Males are more commonly affected than females

Peaks in young adults and in elderly

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 Sub-types of GBS

AIDP

MFS GBS AMAN

AMSAN

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 Acute Inflammatory Demyelinating
Polyneuropathy(AIDP)
Prevalent in western countries (90% of the
GBS cases)
Adults are affected more than the children

First attack appears directed against a component

of Schwann cell
 Acute Motor-Sensory Axonal
Neuropathy(AMSAN)

Very rare

Closely related to AMAN

 Adults are mostly affected

Pattern of re-myelination
In GBS primary demyelination of CNS is not found.
Other changes such as degeneration of spinal
posterior tract are secondary to pathology in the PNS

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 Clinical features

Rapidly evolving areflexic ascending motor

paralysis of the extremities ,up to the
tetraparesis

Reduced or absent deep tendon reflexes

 Mild sensory symptoms

 Clinical features cont’d…

Fever
Fatigue
Pain
Bilateral facial palsy
Antecedent symptoms
 Management

MANAGEMENT

MEDICAL REHABILITATION

SPEECH OCCUPATIONAL
PHYSIOTHERAPY THERAPY THERAPY
 Physiotherapy Management

PT
MANAGEMENT

ONGOING/LONG-
SUBACUTE
ACUTE PHASE TERM REHAB
REHAB PHASE
PHASE III
 Double knee-and-hip flexion

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 Knee rolling

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 NECK MOVEMENTS

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• Risk of hypotension is reduced by ;
 Ensuring that turning is gentle
 Avoiding any intervention if CVP is below
 5cmH2O
 Acclimatization to the upright posture with a tilt
table
 Risk of bradycardia is reduced by oxygenation
before and after suction

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 PROGNOSIS
The length of time and the amount of effort required to bring
about the best possible recovery varies among individuals and
is related primarily to the severity of the symptoms.

About 30% of persons affected with GBS have some degree

of residual weakness after three years.

3 - 5% may suffer a relapse many years later.

1- 5% of cases are fatal, usually due to respiratory or

cardiac complications.

Most people, however, are able to recover completely and lead

normal lives.
 REFRENCES

Guillain-Barre syndrome: pathological, clinical, and

therapeutical aspects
By Silvia Iannello
PNF in practice –An illustrated guide
Adler ,Beckers ,Buck
Therapeutic exercises
Kisner
http://neurologychannel.com/guillain
http://en.wikipedia.org/wiki/guillain-barre-syn
drome/

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