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Diarrhea in Children
Diarrhea in Children
08immn10
GENERAL OBJECTIVES
To know abut the causes of diarrhoea and thereby
prevent the mortality rate in children.
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Chronic Diarrhoea
Diarrhoea which lasts for more than 4 weeks
Most of the causes are non-infectious
Persistent Diarrhoea
-Diarrhoea lasting between 2 to 4 weeks
Etiology
Bacterial infections.
Viral infections.
Parasites .
Functional bowel disorders.
Intestinal diseases.
Food intolerances and sensitivities.
Reaction to medicines.
Clostridium perfringens
Staphylococcus aureus
Rota virus
Campylobacter bacteria
Shigella bacteria
Clinical features
Stools
Loose
Blood stained
Offensive smell
Steatorrhea (floating, oily, difficult to flush)
Sudden onset of bowel frequency
Crampy abdominal pain
Urgency
Fever
Loss of appetite
Loss of weight
Contd….
Signs of dehydration in infants and young children
include:
dry mouth and tongue
no tears when crying
no wet diapers for 3 hours or more
sunken eyes, cheeks, or soft spot in the skull
high fever
listlessness or irritability
Children with any of the following symptoms should
see a health care provider:
signs of dehydration
diarrhea for more than 24 hours
a fever of 102 degrees or higher
stools containing blood or pus
stools that are black and tarry
If children have diarrhea, parents or caregivers should
not hesitate to call a health care provider for advice.
Diarrhea is especially dangerous in newborns and
infants, leading to severe dehydration in just a day or
Pathophysiological mechanism of diarrhoea
Osmotic
eg Lactose intolerance
Secretory
eg Cholera
Mixed secretory-osmotic
eg Rotavirus
Mucosal inflammation
eg Invasive bacteria
Motility disturbance
Diagnosis
Medical history and physical examination. The doctor will ask about eating
habits and medication use and will perform a physical examination to look for
signs of illness.
Stool culture. A sample of stool is analyzed in a laboratory to check for
bacteria, parasites, or other signs of disease and infection.
Blood tests. Blood tests can be helpful in ruling out certain diseases.
Fasting tests. To find out if a food intolerance or allergy is causing the diarrhea,
the doctor may ask a person to avoid foods with lactose, carbohydrates, wheat,
or other ingredients to see whether the diarrhea responds to a change in diet.
Sigmoidoscopy or colonoscopy. These tests may be used to look for signs of
intestinal diseases that cause chronic diarrhea. For sigmoidoscopy, the doctor
uses a thin, flexible, lighted tube with a lens on the end to look at the inside of
the rectum and lower part of the colon. Colonoscopy is similar to
sigmoidoscopy, but it allows the doctor to view the en
complications
Dehydration
Excessive loss of fluids and minerals (electrolytes) from the
body
Common in infants and young children with viral
gastroenteritis or bacterial infection
Kidney failure, eg in infection by E.coli
Electrolyte deficiency
Irritation to anus due to frequent passage of watery
stool containing irritating substances
When treatment is needed?
Severe or prolonged episode of diarrhoea
Fever
Repeated vomiting, refusal to drink fluids
Severe abdominal pain
Diarrhoea that contains blood or mucus
Sign of dehydration
Dry, sticky mouth
Few or no tears when crying
Sunken eyes
Lack urine or wet diaper
Dry, cool skin
Fatigue or dizziness
Management
Aims/Goals of management:
Prevent, identify and treat dehydration
Eradicate causative pathogens
Tetracycline, Ciprofloxacin
Prevent spread by early recognition and
institution of infection-control measures
immunization, chemoprophylaxis, good hygiene,
improve sanitation
Management contd…..
Replace the fluids and electrolytes which are lost
Drug therapy has very little place
Antibiotic
Antisecretory
Antimotility
Nutritional management
Follow-up to ensure recovery
Recent reasearch abstract
Abstract
Aims: To examine the effect of the daily use of micronutrients (including zinc) or the same
micronutrients plus heat inactivated lactic acid bacteria (LAB), on diarrhoea in children
compared to placebo.
Methods: A triple blind randomised clinical trial in an urban slum of Karachi, Pakistan.
Micronutrients (including zinc), micronutrients (including zinc and LAB), or placebo, were
provided daily for two months to 75 young children (aged 6–12 months) identified at high
risk for diarrhoea related mortality on the basis of history of at least one episode of
diarrhoea in the preceding two weeks. The longitudinal prevalence of diarrhoea was defined
as the percentage of days a child had diarrhoea out of the days the child was observed.
Results: Mean longitudinal prevalence of diarrhoea in the micronutrient–zinc group was
15% (SD = 10%) child-days compared to 26% (SD = 20%) child-days in the placebo group
and 26% (SD = 19%) child-days in the micronutrient–zinc–LAB group. The difference
between the micronutrient–zinc–LAB and placebo groups was not significant.
Conclusion: The daily provision of micronutrients (including zinc) reduces the
longitudinal prevalence of diarrhoea and thus may also reduce diarrhoea related mortality
in young children; heat inactivated LAB has negative effects in these children.
conclusion
Two recent advances in managing diarrhoeal disease – newly formulated oral
rehydration
salts (ORS) containing lower concentrations of glucose and salt, and success
in using zinc
supplementation – can drastically reduce the number of child deaths. The new
methods,
used in addition to prevention and treatment of dehydration with appropriate
fluids,
breastfeeding, continued feeding and selective use of antibiotics, will reduce
the duration
and severity of diarrhoeal episodes and lower their incidence. Families and
communities
are key to achieving the goals set for managing the disease by making the new
recommendations routine practice in the home and health facility
1. Wikipedia
http://en.wikipedia.org/wiki/Main_Page
2. Medical Journal Malaysia VOL 62
http://www.mma.org.my
3. World Health Organization – WHO
http://www.who.int/topics/diarrhoea/en/
4. http://www.medicinenet.com/diarrhea/article.htm
5. http://www.mayoclinic.com/health/diarrhea/DS002
92
6. http://www.kidshealth.org/parent/infections/commo
n/diarrhea.html
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