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  • Dacanay Ethambutol 2aph Adr

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    kaukau4ever
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    Ethambutol is used as an anti-tuberculosis drug at a normal dose of 15-25 mg/kg body weight once every 24 hours. One of its adverse drug reactions is optic neuropathy, which can cause loss of vision and is both dose-dependent and related to the duration of treatment. Vision loss typically does not occur until at least 2 months of treatment and is more common in patients receiving daily doses of 25 mg/kg or higher, though some cases have been reported at lower doses as well.

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    Dacanay Ethambutol 2aph adr

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    Ethambutol is used as an anti-tuberculosis drug at a normal dose of 15-25 mg/kg body weight once every 24 hours. One of its adverse drug reactions is optic neuropathy, which can cause loss of vision and is both dose-dependent and related to the duration of treatment. Vision loss typically does not occur until at least 2 months of treatment and is more common in patients receiving daily doses of 25 mg/kg or higher, though some cases have been reported at lower doses as well.

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    20 views3 pages

    Dacanay Ethambutol 2aph Adr

    Uploaded by

    kaukau4ever
    Ethambutol is used as an anti-tuberculosis drug at a normal dose of 15-25 mg/kg body weight once every 24 hours. One of its adverse drug reactions is optic neuropathy, which can cause loss of vision and is both dose-dependent and related to the duration of treatment. Vision loss typically does not occur until at least 2 months of treatment and is more common in patients receiving daily doses of 25 mg/kg or higher, though some cases have been reported at lower doses as well.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
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    Download as pptx, pdf, or txt
    of 3

    Indication: Anti-Tuberculosis

    Normal Dose: 15-25 mg/ kg BW once


    every 24 hours
    10 DACANAY, Christopher Rey L.
    Adverse Drug Reaction
    Optic Neuropathy
    - dose dependent and duration related
    - Ethambutol alters the synaptic connections in the retina and
    induces morphologic alterations on the same area
    -Loss of vision does not tend to occur until the patient has
    been on the drug for at least 2 months
    - The toxicity that can occur to the anterior visual pathway from this drug is
    dose related; patients who are receiving dosages of 25 mg/kg/d or greater
    are most susceptible to vision loss. However, cases of vision loss, even with
    much lower doses, have been reported.

    - Symptoms: Low Visual acuity, loss of vision, red-green color blindness

    Source: Kintanar et al. (1996), Adverse Drug Reactions: Guide to Participating Hospitals. Excel Printing:
    Manila
    Optic Neuropathy by ETHAMBUTOL

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