COVID-19 Vaccination

• Vaccines will be necessary for the development of both

individual protection and population-level herd
immunity.

• The development of a safe and effective COVID-19

vaccine is therefore considered crucial to reduce
transmission of SARS-CoV-2, contain the current
outbreak and help prevent future outbreaks.
(Vaccine) Vaccine Dose Age Efficacy Adverse
platform effects

Pfizer- mRNA 2 doses (30 μg per dose) > 16 95% fever, severe
BioNTech 21 days apart years fatigue,
(BNT162b2) -Intramuscular headache,
Store refrigerated chills
between (-70°C)
Moderna mRNA 2 doses (100 μg per dose) > 18 94.1% fever severe
(mRNA-1273) 28 days apart- years fatigue,
Intramuscular headache,
Store refrigerated myalgias,
between 35.6-46.4°F (2- arthralgias
8°C)

AstraZeneca spike 2 doses 21 days apart- 18-55 70.4% Fatigue,

(AZD1222) protein Intramuscular years old headache,
Store refrigerated and fever
between 2-8°C
• Each vaccine series should be completed with the same
vaccine initially used.
• Pfizer-BioNTech and Moderna are each contraindicated in
individuals with a history of severe allergic reaction to any
component of that specific vaccine.
• All individuals should be monitored for immediate vaccine
reactions following receipt; individuals with history of
anaphylaxis should be monitored for 30 minutes and
others for 15 minutes.
• Vaccine recipients should be advised that side effects are
common and include local and systemic reactions,
including pain at the injection site, fever, fatigue, and
headache. Patients should also be advised regarding
reports of rare adverse effects such as anaphylaxis and
Bell’s palsy.