Retinal Prosthesis: Erica Chin Topics Fall 10

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RETINAL PROSTHESIS
Erica Chin
Topics Fall ‘10
Over 40 million blind in the
world.
Over one million in the U.S.

Only 29% of severely visually impaired are employed

Earn 37% less

Total Impact: $68 billion annually


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What is the Retina?
 Retina
 Neural tissue
 Lines side and back of
cavity

Weiland, 2005
What is the Retina
 Retina
 Neural tissue
 Lines side and back of
cavity
 Multilayered
 200 um thick

Weiland, 2005
Visual Pathway
 Photoreceptors
 Neurons
 Energy Conversion
 Photons
 Neural Signal

 Retinal ganglion cells


 Send signals
 Via optic nerve

Weiland, 2008
Blindness
 Disrupted pathway
 Focus light on retina
 Sense light
 Send visual
information to brain

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Blindness
 Photoreceptor loss
 Age-related macular
degeneration (AMD)
 700,000 /yr (US)
 70,000 legally blind

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Blindness
 Photoreceptor loss
 Age-related mascular
degeneration (AMD)
 700,000 /yr (US)
 70,000 legally blind
 Retinitis pigmentosa
 >100 genetic defects
 1:3500 live births
 Surgery/treatment don’t
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work. Can delay.
Concept of Visual Prostheses

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Videos XD
 Scientific
Frontiers: 4/6/05:
14:06.
 How it Works
 15:19-17.38
 Experiment
 18.33- 20:03
 Alda’s experience
 21:13-22:02
 The Doctors:
July 2010:
 3:26

Weiland, 2005
References
 James D. Weiland, Wentai Liu, Mark S. Humayun. RETINAL PROSTHESIS.
Annual Review of Biomedical Engineering, Vol. 7: 361 -401 (Volume publication
date August 2005)
 Visual Prosthesis. Peter H. Schiller and Edward J. Tehovnik. Perception. Author
manuscript; available in PMC 2010 January 5.PMCID: PMC2801810. Published in
final edited form as: Perception. 2008; 37(10): 1529–1559.
 Weiland, J.D.; Humayun, M.S.; , "Visual Prosthesis," Proceedings of the IEEE ,
vol.96, no.7, pp.1076-1084, July 2008
doi: 10.1109/JPROC.2008.922589
URL: 
http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4539488&isnumber=454
5297
 Scientific Frontiers. “Cybersenses” April, 06, 2005:
http://www.pbs.org/saf/1509/video/watchonline.htm
 The Doctors. “Bionic Eye” July 28, 2010:
http://www.thedoctorstv.com/main/home_page?init_type=Feature&init_id=816
References
1. http://www.elllo.org/Assets/images/P0751/781-Blindfold.jpg
2. http://acharya.iitm.ac.in/disabilities/braille_big.jpg
3. http
://www.popularmechanics.com/cm/popularmechanics/images
/terms-1-1010-lg.jpg
4. http://
www.ncbi.nlm.nih.gov/books/NBK11145/bin/ch12f2.jpg
5. http://
www.pdazzler.net/wp-content/uploads/2010/05/macdeg.jpg
6. http://www.hakeem-sy.com/main/files/sim-ret.jpg
7. http://www.whatisneuroplasticity.com/images/Axons%20firi
ng%20in%20a%20neural%20cell.jpg

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