ANTIBIOTICS

SENSITIVITY
 ANTIBIOTICSENSITIVITYCHART
Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP
with assistance from Tim Lau
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC
Gram Positive Cocci Gram Negative Bacilli Gram Negative Coccobacilli Anaerobes Atypicals
Streptococci Staphylococci
Non-beta-lactamase producing SPACE
Bacteria Streptococci Staph Community Hospital Beta-lactamase producing Serratia marcescens,
ESBL Mycoplasma
Staph Escherichia coli, (Extended spectrum beta- CRE Below the
(pneumoniae/ Enterococci epidermidis acquired acquired Escherichia coli, Proteus vulgaris, Pseudomonas Above the diaphragm Clostridium pneumoniae, Legionella Chlamydia
aureus (Methicillin (Methicillin
Klebsiella pneumoniae, Acinetobacter sp.,
lactamase producing) (Carapenem-resistant Neisseria meningitidis Neisseria gonorrhea diaphragm
pyogenes/ (Group D strep) (coagulase Klebsiella pneumoniae, Escherichia coli, aeruginosa (Peptostreptococcus) difficile Chlamydophila pneumophila trachomatis
(Methicillin sensitive) resistant) resistant)
Haemophilus influenzae Citrobacter sp., Enterobacteriaceae) (Bacteroides sp)
viridans group) negative) Haemophilus influenzae Klebsiella pneumoniae spp
Enterobacter sp.

Brain, oral, respiratory tract, Intraabdominal, Intraabdominal, pelvic Pelvic inflammatory

Location heart, skin urinary tract
Skin, prosthetics Oral, respiratory tract, heart, skin, bones/joint Brain, respiratory tract, intraabdominal, urinary tract Brain Pelvic inflammatory disease/STI Oral, respiratory tract inflammatory disease
Intraabdominal Respiratory tract
disease/STI

Pencillin V/G Pencillin G-IV Pencillin V/G

Amoxicillin/ampicillin Amoxicillin/ampicillin Ampicillin-IV Amoxicillin/ampicillin
Penicillins Cloxacillin
Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate
Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam
Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin
Cefuroxime Cefuroxime Cefuroxime Cefuroxime
Cefoxitin Cefoxitin Cefoxitin Cefoxitin
Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime
Cephalosporins
Cefixime Cefixime Cefixime
Ceftazidime Ceftazidime
Ceftolozane - tazobactam Ceftolozane-tazo Ceftolozane-tazo
Cefipime Cefipime Cefipime Cefipime Cefipime
Ceftibiprole Ceftibiprole

Meropenem/imipenem/doripe
Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem
nem

Carbapenems Ertapenem Ertapenem Ertapenem Ertapenem

Erythromycin Erythromycin Erythromycin
Macrolides
Clarithromycin/azithromycin Clarithromycin/azithromycin Clarithromycin/azithromycin JUST H.flu JUST azithromycin Clarithromycin/azithromycin JUST azithromycin
Tetracycline/doxycycline Tetracycline/doxycycline Tetracycline/doxycycline JUST H.flu Tetracycline/doxycycline Tetracycline/doxycycline
Tetracyclines
Tigecycline Tigecycline Tigecycline
Ciprofloxacin/norfloxacin BUT JUST bladder infections for norfloxacin Ciprofloxacin
Fluoroquinolones
Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Moxifloxacin Levofloxacin/moxifloxacin

Gentamicin/tobra
Gentamicin/tobramycin/amikacin
mycin/amikacin
Aminoglycosides
Colistin/polymyxi
Colistin/polymyxin B
Polymyxin nB
Lincosamides Clindamycin Clindamycin Clindamycin

Glycopeptides/lipoglycopeptides Vancomycin/daptomycin Vancomycin/daptomycin Vancomycin oral

Oxazolidinones Linezolid/tedizolid Linezolid/tedizolid

Trimethoprim-Sulfamethoxazole Trimethoprim-sulfamethoxazole Trimethoprim-sulfamethoxazole
Chloramphenicol Chloramphenicol Chloramphenicol Chloramphenicol
Metronidazole Metronidazole
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
(JUST BLADDER INFECTIONS) JUST E.faecalis
Rifampin Rifampin Rifampin
Fidaxomicin Fidaxomicin
Cloxacillin and clindamycin typically have less than 40% activity for S.epidermidis, thus usage depends on local susceptibility data
Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium; the antibiotics listed are active against E.faecalis, but have limited activity for E.faecium
Cephalosporins have in-vit ro activity for SPACE organisms but induce production of beta-lactamases
Tigecycline has no activity against Pseudomonas aeruginosa, but for Acinetobacter it depends on local susceptibility data; Tigecycline is active against SPACEorganisms, but for Proteus spp it depends on local susceptibility data

OCTOBER 2019
 ANTIBIOTICSENSITIVITYCHART
Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP
with assistance from Tim Lau
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC
Gram Positive Cocci Gram Negative Bacilli Gram Negative Coccobacilli Anaerobes Atypicals
Streptococci Staphylococci
Non-beta-lactamase producing SPACE
Bacteria Streptococci Staph Community Hospital Beta-lactamase producing Serratia marcescens,
ESBL Mycoplasma
Staph Escherichia coli, (Extended spectrum beta- CRE Below the
(pneumoniae/ Enterococci epidermidis acquired acquired Escherichia coli, Proteus vulgaris, Pseudomonas Above the diaphragm Clostridium pneumoniae, Legionella Chlamydia
aureus (Methicillin (Methicillin
Klebsiella pneumoniae, Acinetobacter sp.,
lactamase producing) (Carapenem-resistant Neisseria meningitidis Neisseria gonorrhea diaphragm
pyogenes/ (Group D strep) (coagulase Klebsiella pneumoniae, Escherichia coli, aeruginosa (Peptostreptococcus) difficile Chlamydophila pneumophila trachomatis
(Methicillin sensitive) resistant) resistant) Haemophilus influenzae Citrobacter sp., Enterobacteriaceae) (Bacteroides sp)
viridans group) negative) Haemophilus influenzae Klebsiella pneumoniae spp
Enterobacter sp.

Brain, oral, respiratory tract, Intraabdominal, Intraabdominal, pelvic Pelvic inflammatory

Location heart, skin urinary tract
Skin, prosthetics Oral, respiratory tract, heart, skin, bones/joint Brain, respiratory tract, intraabdominal, urinary tract Brain Pelvic inflammatory disease/STI Oral, respiratory tract inflammatory disease
Intraabdominal Respiratory tract
disease/STI

Pencillin V/G Pencillin G-IV Pencillin V/G

Amoxicillin/ampicillin Amoxicillin/ampicillin Ampicillin-IV Amoxicillin/ampicillin
Penicillins Cloxacillin
Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate
Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam
Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin
Cefuroxime Cefuroxime Cefuroxime Cefuroxime
Cefoxitin Cefoxitin Cefoxitin Cefoxitin
Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime
Cephalosporins
Cefixime Cefixime Cefixime
Ceftazidime Ceftazidime
Ceftolozane - tazobactam Ceftolozane-tazo Ceftolozane-tazo
Cefipime Cefipime Cefipime Cefipime Cefipime
Ceftibiprole Ceftibiprole

Meropenem/imipenem/doripe
Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem
nem

Carbapenems Ertapenem Ertapenem Ertapenem Ertapenem

Erythromycin Erythromycin Erythromycin
Macrolides
Clarithromycin/azithromycin Clarithromycin/azithromycin Clarithromycin/azithromycin JUST H.flu JUST azithromycin Clarithromycin/azithromycin JUST azithromycin
Tetracycline/doxycycline Tetracycline/doxycycline Tetracycline/doxycycline JUST H.flu Tetracycline/doxycycline Tetracycline/doxycycline
Tetracyclines
Tigecycline Tigecycline Tigecycline
Ciprofloxacin/norfloxacin BUT JUST bladder infections for norfloxacin Ciprofloxacin
Fluoroquinolones
Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Moxifloxacin Levofloxacin/moxifloxacin

Gentamicin/tobra
Gentamicin/tobramycin/amikacin
mycin/amikacin
Aminoglycosides
Colistin/polymyxi
Colistin/polymyxin B
Polymyxin nB
Lincosamides Clindamycin Clindamycin Clindamycin

Glycopeptides/lipoglycopeptides Vancomycin/daptomycin Vancomycin/daptomycin Vancomycin oral

Oxazolidinones Linezolid/tedizolid Linezolid/tedizolid

Trimethoprim-Sulfamethoxazole Trimethoprim-sulfamethoxazole Trimethoprim-sulfamethoxazole
Chloramphenicol Chloramphenicol Chloramphenicol Chloramphenicol
Metronidazole Metronidazole
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
(JUST BLADDER INFECTIONS) JUST E.faecalis
Rifampin Rifampin Rifampin
Fidaxomicin Fidaxomicin
Cloxacillin and clindamycin typically have less than 40% activity for S.epidermidis, thus usage depends on local susceptibility data
Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium; the antibiotics listed are active against E.faecalis, but have limited activity for E.faecium
Cephalosporins have in-vitro activity for SPACE organism s but induce production of beta-lactamases
Tigecycline has no activity against Pseudomonas aeruginosa, but for Acinetobacter it depends on local susceptibility data; Tigecycline is active against SPACEorganism s, but for Proteus spp it depends on local susceptibility data

OCTOBER 2019
 ANTIBIOTICSENSITIVITYCHART
Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP
with assistance from Tim Lau
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC
Gram Positive Cocci Gram Negative Bacilli Gram Negative Coccobacilli Anaerobes Atypicals
Streptococci Staphylococci
Non-beta-lactamase producing SPACE
Bacteria Streptococci Staph Community Hospital Beta-lactamase producing Serratia marcescens,
ESBL Mycoplasma
Staph Escherichia coli, (Extended spectrum beta- CRE Below the
(pneumoniae/ Enterococci epidermidis acquired acquired Escherichia coli, Proteus vulgaris, Pseudomonas Above the diaphragm Clostridium pneumoniae, Legionella Chlamydia
aureus (Methicillin (Methicillin
Klebsiella pneumoniae, Acinetobacter sp.,
lactamase producing) (Carapenem-resistant Neisseria meningitidis Neisseria gonorrhea diaphragm
pyogenes/ (Group D strep) (coagulase Klebsiella pneumoniae, Escherichia coli, aeruginosa (Peptostreptococcus) difficile Chlamydophila pneumophila trachomatis
(Methicillin sensitive) resistant) resistant)
Haemophilus influenzae Citrobacter sp., Enterobacteriaceae) (Bacteroides sp)
viridans group) negative) Haemophilus influenzae Klebsiella pneumoniae spp
Enterobacter sp.

Brain, oral, respiratory tract, Intraabdominal, Intraabdominal, pelvic Pelvic inflammatory

Location
heart, skin urinary tract
Skin, prosthetics Oral, respiratory tract, heart, skin, bones/joint Brain, respiratory tract, intraabdominal, urinary tract Brain Pelvic inflammatory disease/STI Oral, respiratory tract inflammatory disease
Intraabdominal Respiratory tract
disease/STI

Pencillin V/G Pencillin G-IV Pencillin V/G

Amoxicillin/ampicillin Amoxicillin/ampicillin Ampicillin-IV Amoxicillin/ampicillin
Penicillins Cloxacillin
Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate
Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam
Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin
Cefuroxime Cefuroxime Cefuroxime Cefuroxime
Cefoxitin Cefoxitin Cefoxitin Cefoxitin
Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime Ceftriaxone/cefotaxime
Cephalosporins
Cefixime Cefixime Cefixime
Ceftazidime Ceftazidime
Ceftolozane - tazobactam Ceftolozane-tazo Ceftolozane-tazo
Cefipime Cefipime Cefipime Cefipime Cefipime
Ceftibiprole Ceftibiprole

Meropenem/imipenem/doripe
Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem Meropenem/imipenem/doripenem
nem

Carbapenems Ertapenem Ertapenem Ertapenem Ertapenem

Erythromycin Erythromycin Erythromycin
Macrolides
Clarithromycin/azithromycin Clarithromycin/azithromycin Clarithromycin/azithromycin JUST H.flu JUST azithromycin Clarithromycin/azithromycin JUST azithromycin
Tetracycline/doxycycline Tetracycline/doxycycline Tetracycline/doxycycline JUST H.flu Tetracycline/doxycycline Tetracycline/doxycycline
Tetracyclines
Tigecycline Tigecycline Tigecycline
Ciprofloxacin/norfloxacin BUT JUST bladder infections for norfloxacin Ciprofloxacin
Fluoroquinolones
Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Moxifloxacin Levofloxacin/moxifloxacin

Gentamicin/tobra
Gentamicin/tobramycin/amikacin
mycin/amikacin
Aminoglycosides
Colistin/polymyxi
Colistin/polymyxin B
Polymyxin nB
Lincosamides Clindamycin Clindamycin Clindamycin

Glycopeptides/lipoglycopeptides Vancomycin/daptomycin Vancomycin/daptomycin Vancomycin oral

Oxazolidinones Linezolid/tedizolid Linezolid/tedizolid

Trimethoprim-Sulfamethoxazole Trimethoprim-sulfamethoxazole Trimethoprim-sulfamethoxazole
Chloramphenicol Chloramphenicol Chloramphenicol Chloramphenicol
Metronidazole Metronidazole
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
(JUST BLADDER INFECTIONS) JUST E.faecalis
Rifampin Rifampin Rifampin
Fidaxomicin Fidaxomicin
Cloxacillin and clindamycin typically have less than 40% activity for S.epidermidis, thus usage depends on local susceptibility data
Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium; the antibiotics listed are active against E.faecalis, but have limited activity for E.faecium
Cephalosporins have in-vitro activity for SPACE organism s but induce production of beta-lactamases
Tigecycline has no activity against Pseudomonas aeruginosa, but for Acinetobacter it depends on local susceptibility data; Tigecycline is active against SPACEorganism s, but for Proteus spp it depends on local susceptibility data

OCTOBER 2019