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Brain Abscess
Brain Abscess
BRAIN ABSCESS
INTRODUCTION
Brain abscess are the most common
inflammatory condition of the brain and
spinal cord. Inflammation is caused by
bacteria, viruses, fungi and chemicals.cns
infections may occur via the blood stream by
extension from a primary site along cranial
and spinal nerves.
DEFINITION
• Brain abscess is an accumulation of pus with
in the brain tissues that can result from local
or systemic infections
BRUNNER AND SUDARTH
• Brain abscess is defined as purulence and
inflammation in one or more localized region
with in the brain parenchyma.
INCIDENCES
• Approximately 8 % of intracranial masses in
developing countries and 1-2% in western
countries.
• Brain abscess are rare in people who are
immuno competent they are more frequently
diagnosed in people who are immuno
supressed as a result of underlying disease
or medications.
• The mortality rate for inflammatory
conditions of the brain is approximatly 10 to
30 % in the general population.
• It is higher in older patients , up to 19% of
these who recover can have long term
neurologic deficits including hearing loss.
CAUSES AND RISK FACTORS
• Pulmonary infections
• Bacterial endocarditis
• Skull fracture
• Brain trauma
• Brain surgery
• Congenital heart disease
• Cancer and other chronic illness
• Meningitis
• Middle ear infections
• Compromised immune system due to HIV
or AIDS
• Chronic sinus
PATHOPHYSIOLOGY
• Pathogenic organisms enters into brain
tissue through various routes, ear , throat ,
nose or blood stream