Taxonomía y Clasificación: Principales parásitos. Relación con el hospedero.
M. Sc. Robert Caballero Bardales
Docente del Curso de Introd. al Laboratorio Apoptosis: a potential triggering mechanism of neurological manifestation in Plasmodium falciparum malaria Plasmodium falciparum infection can lead to a life threatening disease and the pathogenetic mechanisms of severe manifestations are not fully understood. Here, we investigated the capacity of P. falciparum-parasitized red blood cells (PRBC) from 45 children with clinical malaria to induce endothelial cell (EC) apoptosis. In all subjects, PRBC that cytoadhered to ECs could be found albeit to a variable degree. By contrast, PRBC that induce EC apoptosis were found only in nine (20%) subjects. Interestingly, children with neurological manifestations were significantly more likely to harbour apoptogenic strains. There was no quantitative relationship between the capacity of these isolates to cytoadhere and apoptosis induction. We hypothesize that P. falciparum-encoded molecules could be responsible for apoptosis induction and therefore suggest new insights in the pathogenesis of P. falciparum malaria. Further investigations are currently in progress to determine whether these results can be confirmed and to identify putative parasite apoptogenic factors. Huevo embrionado de A. lumbricoides Radiografía intestinal. Infestacion de adultos de A. lumbricoides Adulto de Enterobius vermicularis Enterobius vermicularis Strongyloides stercolaris Strongyloides stercolaris Huevos de Trichuris trichuria HYMENOLEPIS NANA HYMENOLEPIS NANA TAENIA SAGINATA / T. SOLIUM