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Chapter 02 Pharma
Chapter 02 Pharma
Chapter 02 Pharma
• Drug half-life
• Site of excretion
• Critical concentration
– The amount of a drug that is needed to cause a
therapeutic effect
• Loading dose
– A higher dose than that usually used for treatment
• Dynamic equilibrium
– The actual concentration that a drug reaches in
the body
– Absorption
– Distribution
– Biotransformation
– Excretion
• First-pass effect
• Protein binding
• Blood–brain barrier
• Placenta/breast milk