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BIOPHARMA PRODUCTION

Avantor OmniTop Sample Tubes adjustable volume sampling system (AVSS) 


Designed to sample from your most critical processes

Volumetric Control
FEATURES AND BENEFITS
Customized Sample Volume
Collect only the required sample volume needed for
your analytical process 0.1mL – 15mL
Sample Accuracy
Collected volumes of +/- 0.25mL
Sterile Process Connection

Improving Product Yield


Using our dual filtered air syringes process, inline line
losses are removed improving final product yields.

Closed System Processing


Remove the need for biologic safety cabinets.

Diptube is adjusted to the Easy Operation


No pumps required, collect simply with no extra
desired exact sample volume equipment.

proprietary & confidential


BIOPHARMA PRODUCTION

Exact Volume Sampling is Impactful to Workflow Efficiencies


CUSTOMER CHALLENGE
CHALLENGE AVANTOR SOLUTION RESULT: Value to the Customer

‒ Biomanufacturer sampling prior to ‒ Actual Downstream Sampling ‒ Saving 95mL of Final Product to be filled.
final fill of mAb product. requirements 5mL
‒ Estimated Savings $47,500 per sample
‒ Overfilling during sampling, pulling ‒ Using the AVSS system, they can draw. multiplied by 52/batches per year
100mL of final product extract an exact volume sample – = ~$2.5M of Annual Savings
sampling only what is needed to
‒ Sampling Product Value: $500/mL perform the required assays
= $50,000 Final Product 
‒ Process is operator independent
and repeatable.

Downstream Tests Volume Required for Test

Endotoxin <1ml
5mL
Purity <1ml
total
Concentration <1ml
SEC <1ml
IEC <1ml

proprietary & confidential

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