Professional Documents
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The Anesthesia Preparation
The Anesthesia Preparation
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The Anesthesia Machine
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Objectives
• Anesthesia Machine
• Ventilators
• Scavenging Systems
• System Checkout
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Anesthesia machine
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Anesthesia machine
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Anesthesia machine
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The machine
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The Machine
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Checking the leakage
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Mesin anestesi
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Ventilators
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Scavenging Systems
• Protects the breathing
circuit or ventilator
from excessive positive
or negative pressure.
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Scavenging Systems
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Checking Anesthesia Machines
8 Categories of check:
• Emergency ventilation equipment
• High-Pressure system
• Low-Pressure system
• Scavenging system
• Breathing system
• Manual and automatic ventilation system
• Monitors
• Final Position
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Video 1
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Airway intubation
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Anatomy
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ANATOMY OF AIRWAY
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Methods
E ndotracheal intubation
◦ Orotracheal
◦ Nasotracheal
Cricothyrotomy
Tracheotomy
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Endotracheal Intubation
• Placement of a flexible plastic tube into the
trachea to:
– maintain an open airway,
– serve as a conduit through which to administer certain
drugs.
• Is performed in critically injured, ill or
anesthetized patients:
– to facilitate ventilation of the
lungs, including mechanical ventilation,
– to prevent the possibility of
asphyxiation or airway obstruction.
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Indications:
For supporting ventilation in patient with pathologic disease:
◦ Upper airway obstruction,
◦ Respiratory failure,
◦ Loss of consciousness
◦ Type of surgery:
Operative site near the airway,
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Before we do the intubation, we should evaluate the difficult airway
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The Difficult Airway
SAKLES’ TRIANGLE
Difficult Bag and
Mask Ventilation
Difficult Laryngoscopy
and Intubation
Difficult
Cricothyrotomy
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OBESE score for
Difficult Mask Ventilation
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The Obese patient
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The Elderly Patient
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How to predict:
T H E D IFFIC U L T
I N T U B AT I O N
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Difficult Intubation
L E MON score
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GUIDELINES FOR
DIFFICULT INTUBATION
Difficult Airway Society Flowchart for
difficult intubation (2004)
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Airway Assessment
1) Condition that associated with difficult intubation:
• Congenital anomalies Pierre
Robin syndrome, Down’s
syndrome
• Infection in airway
Retropharyngeal abscess,
Epiglottitis
• Tumor in oral cavity or larynx
Enlarge thyroid gland trachea shift
to lateral or compressed tracheal
lumen
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Airway Assessment
2) Interincisor gap : normal more than 3 cms
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3) Mallampati classification: Class 3,4 may be
difficult intubation
Soft palate
Uvula
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Laryngoscopic view
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6) Movement of temperomandibular joint (TMJ)
Grinding
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P R E P ROC E D U R A L
E V A L U ATION
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Pre Procedural Evaluation
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Preparing the procedure
Essentials: S A L T
Suction. This is extremely important. Often patients will have material in the
pharynx, making visualization of the vocal cords difficult.
Airway. the oral airway is a device that lifts the tongue off the posterior
pharynx, often making it easier to mask ventilate a patient. The inability to
ventilate a patient is bad. Also a source of O2 with a delivery mechanism
(ambu-bag and mask) must be available.
Tube. Endotracheal tubes come in many sizes. In the average adult a size
7.0 or 8.0 oral endotracheal tube will work just fine.
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Or STATICS
• S Scope : laryngoscope and stethoscope
• T Tube : endotracheal tube
• A Airway : oropharyngeal (OP) and
nasopharyngeal (NP)
• T Tape : for strapping OP/NP tube
• I Introducer : stylet
• C Connector : for masking
• S Suction
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EQ U I P MENT
I N T U B ATION
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Intubation
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1) Laryngoscope : handle and blade
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• Laryngoscope : handle
and blade
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LARYNGOSCOPIC BLADE
Macintosh (curved) and Miller (straight) blade
Adult : Macintosh blade, small children : Miller blade
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Tube sizes
• Newborn – to 4 kg - 2.5 mm (uncuffed).
• 1-6 months 4-6 kg – 3.5 mm (uncuffed).
• 7-12 months 6-9 kg – 4.0 mm (uncuffed).
• 1 year 9 kg – 4.5 mm (uncuffed).
• 2 years 11 kg – 5.0 mm (uncuffed).
• 3-4 years 14–16 kg - 5.5 mm (uncuffed).
• 5-6 years 18–21 kg – 6.0 mm (uncuffed).
• 7-8 years 22-27 kg – 6.5 mm ( uncuffed).
Tube sizes
• 9-11 years 28-36 kg – 7.0 mm(cuffed).
• 14 to adults 46+ kg – 7.0 – 80 mm (cuffed).
• Adult female 7.0 – 8.0mm (cuffed).
• Adult male 7.5 – 8.5 mm (cuffed).
2) Material : Red rubber or PVC
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4) Bevel
5) Murphy’s eye
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Cuffed and Uncuffed
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Cuffed
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Uncuffed
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Kinking
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Non kinking
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6) Depth of endotracheal tube : Midtrachea or
below vocal cord ~ 2 cms
Adult -> Male = 23 cms ,Female = 21 cms
Children
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7) Tube markings
Z-79
Disposible (Do not reuse)
Oral/Nasal
Radiopaque marker
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3) Other equipments
3.1 Stylet
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3.2 Oropharyngeal or nasopharyngeal airway
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3.3) Suction catheter
3.4) Slip joint connector
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4 Rules of Suctioning
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3.7) Syringe
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4. Monitoring success of
endotracheal intubation
• 4.1) Stethoscope
4.2) Endtidal - CO2
4.3) Pulse oximeter
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Instruments used...
1. Self-refilling bag-valve combination
(eg, Ambu bag) or bag-valve unit
(Ayres bag), connector, tubing, and
oxygen source. Assemble all items
before attempting intubation.
2. Tincture of benzoin and precut tape.
Sniffing position
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Topical Anesthesia: Anesthetize
the mucosa of the oropharynx,
and upper airway with
lidocaine 2%, if time permits
and the patient is awake.
Direct Laryngoscopy:
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Curved blade technique
f) The anesthesiologist then takes the endotracheal tube, made of
flexible plastic, in the right hand and starts inserting it through the
mouth opening.
g) The tube is inserted through the cords to the point that the cuff
rests just below the cords
h) Finally, the cuff is inflated to provide a minimal leak when the bag is
squeezed
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Straight blade technique
Follow the steps outlined for curved blade technique, but
advance the blade down the hypopharynx, and lift the
epiglottis with the tip of the blade to expose the vocal
cords.
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Laryngoscopic View Grades
Grade 1: Full aperture visible
Grade 2: Lower part of cords visible
Grade 3: Only epiglottis visible
Grade 4: Epiglottis not visible
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Mallampati and Direct View
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Complications:
1. Tube malpositioning (esophageal intubation )
2. Tube malfunction or physiologic responses to airway
instrumentation
3. Trauma such as tooth damage, lip/tongue/mucosal laceration,
sore throat, dislocated mandible
4. Mucosal inflammation and ulceration and excoriation of nose
can occur while the tube is in place
5. Laryngeal malfunction and aspiration, glottic, subglottic or
tracheal edema and stenosis, vocal cord granuloma or paralysis
during extubation
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Video 2
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Laryngeal Masks (LMA)
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Laryngeal Masks
Short Procedure:
1. The cuff of the mask is deflated
Indications: before insertion and lubricated.
When endotracheal intubation 2. The patient is sedated or fully
is not necessary or it’s difficult anaesthetized if conscious, and their
neck is extended and their mouth
Contraindications:
opened widely.
• Non-fasted patients 3. The apex of the mask, with its open
• Morbidly obese patients end pointing downwards toward the
• Obstructive or abnormal tongue, is pushed backwards towards
lesions of the the uvula.
oropharynx 4. The cuff follows the natural bend of
the oropharynx, and its long walls
Air entry is confirmed by come to rest over the piriform fossa.
listening for air entry into the 5. Once placed, the cuff around the
lungs with a stethoscope mask is inflated with air to create a
tight seal.
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Advantages vs. Disadvantages
Advantages:
•Allows rapid access
•Does not require laryngoscope
•Relaxants not needed
•Provides airway for spontaneous or controlled
ventilation
•Tolerated at lighter anesthetic planes
Disadvantages:
• Does not fully protect against
aspiration in the non-fasted
patient
• Requires re-sterilization
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Nasoendotracheal intubation
Advantages:
1) Comfortable for prolong intubation in postoperative period
2) Suitable for oral surgery : tonsillectomy , mandible surgery
3) For blind nasal intubation
4) Can take oral feeding
5) Resist for kinking and difficult to accidental extubation
Disadvantages:
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Contraindication
for nasoendotracheal intubation
4) Retropharyngeal abscess
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Complication of endotracheal intubation
1) During intubation
2) During remained intubation
3) During extubation
4) After extubation
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During intubation
Trauma to lip, tongue or teeth
Hypertension and tachycardia or arrhythmia
Pulmonary aspiration
Laryngospasm
Bronchospasm
Laryngeal edema
Increased intracranial pressure
Spinal cord trauma in cervical spine injury
Esophageal intubation
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During remained intubation
Obstruction from klinking , secretion or overinflation of cuff
Pulmonary aspiration
During Extubation
• Laryngospasm
• Pulmonary aspiration
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After Extubation
• Sore throat
• Hoarseness
• Tracheal stenosis (Prolong
intubation)
• Laryngeal granuloma
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IF
Endotracheal Intubation fails,
you must have a back-up plan
• BVM • LMA
• Combi-tube • Cricothyrotomy
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Cricothyrotomy
• Incision made through the skin and cricothyroid membrane to
establish a patent airway during certain life-threatening situations,
such as airway obstruction by a foreign body, angioedema, or
massive facial trauma.
• Is easier and quicker to perform than tracheotomy, does not
require manipulation of the cervical spine and is associated with
fewer complications.
• Used almost exclusively in emergency circumstances
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Tracheostomy
Making an incision on the front of the neck and opening a
direct airway through an incision in the trachea.
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Conclusion
Do not attempt intubation unless you are totally skilled, rather perform bag-valve-
mask ventilation.
• Intravenous (IV)
• Inhalational
Types of General Anesthetics
• Induction agents
– Induction agents usually administered IV
– can be inhalational for those who do not tolerate
IV access
• Maintenance agents
– Maintenance agents usually administered
inhalationally or IV with bolus or continuous
infusion technique
General Anesthetics-Intravenous Agents
• Benzodiazepines
– Rarely used alone for general anesthesia
• Cannot easily induce and maintain general anesthesia
• Lack analgesic properties
– Used for sedative and amnestic effects
• Opioids
– Decrease MAC of inhalation agents
– Primarily used as adjuncts
– Respiratory depression
General Anesthetics-Intravenous Agents
• Ketamine
– Duration of anesthesia 5-20 minutes
– Metabolized in the liver
– Increase in HR, BP, and CO due to
sympathomimetic effects
– Do not use in patients that will not tolerate above
– Stimulates salivary secretions
– Emergence phenomenon 5-30%
General Anesthetics-Intravenous Agents
• Ketamine
– “Dissociative anesthesia”
• Amnesia
• Analgesia
• Catalepsy
– Thalamoneocortical and limbic systems
– Protective reflexes maintained
– NMDA antagonist
General Anesthetics-Intravenous Agents
• Ketamine (cont.)
– Affects mu opioid receptors
– Onset and peak plasma concentrations
• 1 minute after IV
• 5-15 minutes after IM
• 30 minutes after oral
– Distributional half life 11-16 minutes
– Elimination half life 2-3 hours
General Anesthetics-Intravenous Agents
• Methohexital
– 2.5 times more potent than thiopental
– Shorter duration of action
– Sleep time 5-7 minutes
– Mean elimination half life 3.9 hours
– Biotransformed in the liver
– Excitatory phenomena
– Most often used GA in OMS
General Anesthetics-Intravenous Agents
• Propofol
– Unrelated to other general anesthetics
– Oil in water emulsion
– Rapid onset
– Distributional half life 1-8 minutes
– Terminal elimination half life 4-24 hours
– Extensive plasma and tissue protein binding
General Anesthetics-Intravenous Agents
• Propofol (cont.)
– Disappears from bloodstream more rapidly than
thiopental
– Decreases MAP 20-30 %
– Apnea 22-45% after induction dose
– Pain on injection
– Less N & V
– Discard unused portion after 6 hours
Inhalational General Anesthetics
Inhalational Anesthetics Uptake and
Distribution
• Nitrous Oxide
– MAC is 105%
– Blood/gas partition coefficient 0.47
– With other Gas, concentration is 50-70%
– Little effect on respiration
– Eliminated unchanged
– Dysphoria and nausea with increased concentrations
– Diffusion hypoxia
– Can induce changed in folate and amino acid metabolism
General Anesthetics-Inhalational Agents
• Sevoflurane
– MAC 2.05%
– Mild airway irritant
– Suitable for mask induction
– Rare hepatotoxicity
Inhalational Agents
• Desflurane
– Blood gas partition coefficient 0.42
– Irritating to airway
– MAC 6%
– Required heated vaporizer
– Expensive compared to other anesthetic gases
– Reduces SVR and MAP, but increase in heart rate causing stable
CO
– Low risk of hepatotoxicity
– Rapid depth and recovery
Inhalational Agents
• Isoflurane (Forane)
– Anesthesia of choice – Dose dependent
depression of
– Blood/gas partition
myocardial contractility
coefficient 1.4 MAC
– Coronary vasodilation
1.15%
– CO maintained
– “Pungent” odor
– Can use
– Can provide muscle catecholamines
relaxation (high – Respiratory depression
concentrations) – Neither nephrotoxic or
hepatotoxic
Inhalational Agents
• Halothane
– Halogenated hydrocarbon
– MAC is 0.75%
– Blood/gas partition coefficient 2.3
– Poor analgesic properties
– Incomplete muscle relaxation
– Decreased MAP
– Depressant effect on myocardial contractility
Inhalational Agents
• Halothane (cont.)
– Vasodilator
– Depressant effect on respiration
– Elimination-alveolar excretion and hepatic
metabolism
– Sensitizes heart to catecholamines
– Associated with hepatoxicity
– Malignant hyperthermia
Anesthesia drugs in
RSUD Ulin Banjarmasin
Pembimbing:
dr. Mahendratama Purnama Adhi,
SpAn
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Anesthesia drugs
• Induction
• Muscle Relaxant
• Emergency drugs
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Induction drugs
• IV
– Ketamin
– Propofol
• Inhalation
– Halotan/Fluothan
– Nitrous Oxide (H2O)
– Ether
– Enfluran
– Isofluran
– Sevofluran
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Ketamin
• Dosage: 1-2 mg/kgBB
• Onset: 30 sec
• Duration: 15-20 minutes
• Provided in vial packaging with dose 10mg/ml
(Usually it is diluted in 10 cc syringe)
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Ketamin
• Have the strong effect of analgesic, mainly for
somatic pain, but not for visceral pain.
• Lack in hypnotic effect, do not have relaxation
effect, can cause respiratory depression if overdose.
• Causing dream dissociation, disorientation,
hallucination and anxiety.
• Elevate systolic pressure by 20-25%, increase heart
rate.
• Increas blood glucose by ± 15%
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Propofol
• Dosage: 2-2,5 mg/kgBB
• Onset: 2 min
• Duration: 30-45 min
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Propofol
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Halothan/Fluothan
• Pros:
– Fast to induce patient to sleep
– Not stimulating respiratory tract
– Minimal salivation
– Bronchodilator
– Fast recovery time ( 1 hour post anesthesia )
– Minimal effects of nauseous and vomitus
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Halotan/Fluothan
• Cons:
– Need another anesthetic drugs to work better
– Cause hypotension because of myocard
depression and vasodilation
– Heart arythmia
– Not a good analgesic
– Expensive
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N2O
• It smells, non-flammable, and tidak mudah
terbakar, and insoluble in blood.
• Has a strong effect of analgesic (the same level
with morphine but with a weak hypnotic effect
and do not have relaxation effect.
• Need to be given with O2 minimally 255
because it can cause depression and dilatation
of heart and damaging the Central Nervous
System (CNS).
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Ether
• Uncolored, volatile and flammable
• Fulfilled the triad of anesthesia
• Has the strong effect of analgesic
• Can cause respiratory tract irritation and
secretion of bronchus glands
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Enfluran
• Isofluran isomer
• Non-flammable and it smells
• With high level of dose was thought can cause
brain waves activity like seizure (in EEG).
• Respiratory distress and depression of
circulation are stronger than halotan and also
more irritative
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Isofluran
• Clear liquid, it smells strong, non-flammable in
room temperature
• At level 2 for its high stabilisation and can
stand for 5 years in storage or from sun light
exposure.
• The use of muscle relaxant dosage is reduced
to 1/3 dose
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Sevofluran
• Its smell is not that strong comparing to
Isofluran, it has bronchodilator effect so it’s
chosen by many to induce patients (children
and adults) by using facemask.
• There is no reports about immune-mediated
hepatitis before for using sevofluran.
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Muscle Relaxant
• Atracurium (Tramus)
• Rocuronium (Roculax)
• Cisatracurium
• Pancuronium
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Atracurium
• Dosage: 0,5 mg/kgBB
• Onset: 3-5 min
• Duration: 15-30 min
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Atracurium, Side effects & clinical
consideration
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Rocuronium
• Dosage:
– Intubation: 0,6-1,2 mg/kgBB IV
– Maintenance: 0,1-0,2 mg/kgBB bolus (adults)
0,075-0,125 mg/kgBB (children)
• Onset: 1-2 min
• Duration: 15-30 min
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Emergency drugs
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Nama Berikan bila
Efe drin TD menurun >20 % dari T D awal
(biasanya bila T D si s t o l < 9 0
d i be r i k a n)
Dosis: 5-10 mg IV
Su l f a s a t r o p i n Br a d i k a r d i (< 6 0 )
D o s i s : 0 , 1 m g IV
Amin of ilin Bronkokonstriksi
Dosis:5mg/kgBB
Dexamethason R e a k s i a n a f il a k s i s
Dosis:1 mg/kgBB
Adren alin Ca r d i a c a r r e s t
Dosis:1mg/kgBB
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