REASONS FOR

MANUSCRIPT
REJECTION

An Academic presentation by
Dr. Nancy Agnes, Head, Technical Operations, Tutors
India Group www.tutorsindia.com
Email: info@tutorsindia.com
Today's
Discussion
OUTLIN
E
In brief

Introduction

Reasons for manuscript rejection

Conclusion
 In-
Brief

Every researcher wants to see their theory published in a high-impact journal. On

the other hand, publishing a paper is difficult, and manuscript rejection is a frequent
phenomenon in scholarly literature. At some stage in their career, any researcher w
ould have a manuscript rejected. Researchers will learn from their errors and
guarantee that their next novel has a smooth path to print. A list of the utmost common
mistakes that could lead to your manuscript being rejected
 Challenges to translate research studies conducted in the field
of pharmaceutical sciences into published
manuscripts are common.

A research manuscript published in a reputable national

or international journal is known as substantiation of accurate
Introduction and dependable studies conducted by a research group.

Journal papers, reviews, brief letters, commentaries,

proceedings, expert statements, and editorials are
examples of manuscripts written in scholarly journals.

‘Research’ and ‘Review’ articles are the most important and

influential styles among them, and they are widely
published, read, and popularised.
 There are a variability of explanations for this; the most common
(non-limiting) ones are discussed below:
1. LACK OF NOVELTY, ORIGINALITY, AND PRESENTATION OF
AN OBSOLETE STUDY

Reasons The key criteria that a science journal editor emphasizes the
for most are novelty and non-obviousness.

manuscript Unless the researcher shows something different, adding to the

rejection existing experience, a mouth dissolving tablet formulation of drug-
using traditional techniques, technologies, and proven excipients
adds little innovation to the existing state of the sector.

Furthermore, introducing an out-of-date analysis when newer

approaches are now available has little to no experimental merit.
2. IMPROPER RATIONALE
The purpose of the analysis is to make a point with proper justifications and adequate
evidence.

A controlled release formulation of a nearly water insoluble medication may be refused right
away on these grounds.

The rationale, which should be the article’s core subject, should focus on the whole
manuscript.

The last sentence in the introduction section should usually include the goal and
objective.

Rejection is caused by a lack of emphasis and an inability to stick to the manuscript’s theme..
3. UNIMPORTANT AND IRRELEVANT SUBJECT MATTER
Peer-reviewed journal publications disseminate information.

As a result, a manuscript must have considerable empirical merit to be published in a well-

recognized, international journal.

Again, the publisher is on the lookout for anything novel that still meets the standards of his
journal’s reach.
4. Flaws in methodology
Any manuscripts show that the work performed in the research sample was done
incorrectly.

It is due to the researcher’s lack of expertise, as shown by the preliminary literature survey
conducted before beginning the project.
It is due to the researcher’s lack of expertise, as shown by the preliminary literature survey
conducted before beginning the project.

A 300 mg tablet prepared with an 8 mm circular punch would have an increased

thickness and is thus unsuitable for preparation.

If this is seen in the manuscript, it will give the reviewers an unscientific interpretation.

If a study’s approach is flawed or doubtful, the results are almost certain to be flawed or
questions as well, and even widely regarded peer-reviewed publications will not consider
such a study.
5. LACK OF INTERPRETATIONS

The researcher must have adequate knowledge to interpret the precise explanations for the
study’s findings.

Even if the findings aren’t quite what the author anticipated, the author should objectively
understand the reason in the discussion section.

It is not enough to demonstrate good results. If the root cause of the negative effects is
correctly interpreted, manuscripts will support future study.
6. INAPPROPRIATE OR INCOMPLETE STATISTICS

The use of statistics in the methodology and findings pages of a manuscript gives it an
advantage over the competition since statistics are already in demand.

The risk of the manuscript being accepted would be increased if the data are presented
precisely, and mathematical rules are applied.
7. REVIEWERS FIELD OF KNOWLEDGE AND DISCRETION

Occasionally, a manuscript may be submitted to a reader who is not an authority in the area of
the matter under consideration.
 He may send the manuscript a glance before determining its fate.

In such circumstances, it is expected that the manuscript has a better probability of

being accepted; however, the reverse may also happen.
8. INAPPROPRIATENESS FOR THE JOURNAL

Before determining whether to submit a research report for review, the Editor-in- Chief
considers its content about that of the journal.

If the manuscript is unusual, some journals will research lead molecules rather than
known and proven drug molecules.

The date of publication and the importance of the subject matter published in a
journal are also important considerations.
9. LACK OF IN VIVO STUDIES
With the introduction of advanced in vivo drug measurement technology and
methods for estimating drug concentrations in minute amounts in a specific
subject, a manuscript is handicapped if the in vitro data is not supported by
applicable in vivo observations and correlations.

Acceptance of manuscripts based solely on data produced by in vitro

assessments is difficult in the current environment.
10. INAPPROPRIATE PACKAGING OF THE MANUSCRIPT
A less-than-borderline paper may be accepted in certain situations if it is well-
packaged.

It may be difficult for an assessor to tell the difference between “introduction” and
“discussion” in some situations.
The introduction aims to present the research topic and to state the article’s
objective(s) or goal(s).

The aim of the ‘discussion’ is to analyze the study, make comparisons to

previous experiments, and analyzing the findings.

The ‘materials and procedures’ section should be comprehensive enough for every
student to replicate the analysis. In reality, this is useful for confirming the study’s
authenticity.

The ‘Discussion’ must be relevant to the research.

11. JOURNALS POPULARITY AND THE PRIORITY IS GIVEN TO THE
MANUSCRIPT BY THE EDITOR

Some manuscripts have potential, but due to the status of the journal and the vast
number of hits to the journal, prospective manuscripts must be rejected because
they face stiff competition from the Editor-in-higher-graded Chief’s research
manuscripts.

If a thesis is rejected on these points, it will eventually find a home in another well-
regarded publication.
Table: 1 common reason for manuscript rejection
 Some manuscripts have potential, but due to the status of
Reasons the journal and the vast number of hits to the journal,
for prospective manuscripts must be rejected because they face
stiff competition from the Editor-in-higher-graded Chief’s
manuscript research manuscripts.
rejection
If a thesis is rejected on these points, it will eventually
find a home in another well-regarded publication
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