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Regulationofblood-Pressure - HND
Regulationofblood-Pressure - HND
Regulationofblood-Pressure - HND
a. Definition
b. Regulation
Mechanisms of B.P Regulation
Nervous mechanism for B.P regulation
a. Baro-receceptor Mechanism
b. Chemoreceptor mechanism
Renal mechanism for B.P regulation
Hormonal Mechaism
Local Mechanism
Reflexes and Responses
Marey Reflex
Atrium-brainbridge Reflex
Bezold-Jarisch Reflex
Definition
:
• Arterial blood pressure is defined as the lateral pressure exerted by
column of blood on wall of arteries.
the
Vasomotor System
Vasomotor system includes three components:
1. Vasomotor center (control heart rate)
2. Vasoconstrictor fibers (vasoconstriction)
3. Vasodilator fibers (vasodilation)
nucleus of
Reduces vasomotor inhibition of tractus solitarius acts
. tone vasoconstrictor area on vasomotor
excites vasodilator area center
Local vasoconstrictors
• Are also called EDCF (endothelium derived
constricting factors) as they are derived from vascular
endothelium.
• Common EDCF are ET1, ET2 & ET3.
• Produced by stretching of blood vessels &
cause vasoconstriction.
Vasodilators of metabolic origin:
carbon monoxide, lactate, H+ & adenosine.
Vasodilators of Endothelial
origin:
• Nitroxides
• NO3 (nitrate)
• NO+
NO- (nitroxyl
(nitrosonium ion)
anion)
• Hypertension
• Hypotension
• Hypertension; when systolic pressure remain
elevated above 150 mm Hg and diastolic
pressure remains 90 mm Hg is called
hypertension.
• Hypotension; when the systolic pressure
is less then 90 mm Hg is called
hypotension.