‫بسم هللا الرحمن الرحيم‬

Vasomotor center

Abu ahmed
2019
The heart rate control by
neural reflexes which is
integrated in vasomotor
center.
Vasomotor center is located
in the medulla oblongata and
regulates CVS .
The vasomotor center made of:-
◦ Vasoconstrictor area:-
sympathetic outflow to vessels.
increase sympathetic out flow to
vessels cause vasoconstriction.
decrease sympathetic out fllow
cause vasodilation.
 ◦ Cardiac acceleratory area:-
Increase sympathetic outflow to
the heart increase heart rate.
◦ Cardiac inhibitory area:-
 increase parasympathetic out
flow to the heart decrease heart
rate.
The vasomotor centers
receives signals input from:
1.Higher brain centers:- which
mediate heart rate change by
emotion.
The higher brain center consist
of:
 Hypothalamus
 Limbic system
 Cerebral cortex
2.Baroreceptors
3.Chemoreceptors
4.Propriocepters
5.Volume receptors
 Higher brain centers

baroreceptors Propriocepters

Vasomotor center

chemoreceptors
Volume receptors
 Baroreceptors
They are mechanoreceptors
Stimulated by stretching of
blood vessel by high blood
pressure.
Located at aortic and carotid
sinuses.
Baroreceptors signals Inhibit
vasoconstrictor &
cardioaccelerator areas and
Stimulate cardioinhibtory
area.
Baroreceptors response to
sustained high pressure
decrease with time and lead
to resetting of Baroreceptors.
 Vasomotor center

efferents
Stimulation of
afferents parasympathetic
Inhibition of
sympathetic

receptors Effectors
Baroreceptors
Heart
stimulation Blood vessels decrease heart rate
Vasodilatation Decrease contractility
venodilatation And stroke volume
 Baroceptors
When increased BP Carotid Aortic arch
sinus baroceptors
baroceptors

Carotid sinus nerve

glossopharyngeal nerve
+ +Vagus nerve

Medulla
Nucleus tractus solitarius
+ -
Cardiac Cardiac Vaso
inhibitory accelerator constrictor

Dilation

myocardium & Sinoatrial Contract- Arterioles Veins

Blood Vessels node ility

- Heart - Blood vessels

 Baroreceptors
when decreased BP Carotid Aortic arch
sinus baroceptors
baroceptors

Carotid sinus nerve

glossopharyngeal nerve
- - Vagus nerve

Medulla
Nucleus tractus solitarius
- +
Cardiac Cardiac Vaso
inhibitory accelerator constrictor

constriction

myocardium and Sinoatrial Contract- Arterioles Veins

Blood Vessels node ility

+ Heart + Blood vessels

 Chemoreceptors
Are detect change in PO2&
PCO2 in the arterial blood.
Found in carotid and aortic
bodies
Stimulated by:-
◦ Low PaO2
◦ High PaCO2
◦ Low pH (high {H+})
Stimulation of chemoreceptors
leads to:-
Stimulation of Cardiac accelerator
and vasoconstrictor area.
inhibition of cardioinhibitory area
 Proprioceptors
In joint , tendons,
muscles and ligaments.
Stimulated by movement
Send excitatory impulses
to vasomotor center to
increase HR in response to
exercise.
 Volume Receptors
They are called low
pressure baroreceptors.
Located with in the atria
and large thorax veins.
Stimulated by volume not
pressure.
Monitor blood volume.
When the heart rate is low
the blood accumulate in
veins produce a reflex
increase in the heart rate.
This called Bain Birdge
Reflex.
Component of Bain Birdge
Reflex
Receptors: volume receptors.
Afferent fibers: vagus nerve.
Controller: VMC.
Efferent fibers: sympathetic
nerve.
Effector: Heart.
Result: increase heart rate.