Supporting Clinical Research

AMIA Joint Summits on Translational Science

Library-based Support for Clinical and Translational Research: The Informationist

Jennifer A. Lyon, MS, MLIS, AHIP

Clinical Research Librarian
UF Health Science Center Libraries
jalyon@ufl.edu
March 10, 2011
 UF Health
Science Center
Six Academic Colleges
Medicine
Shands Healthcare
Nursing
Two Teaching Hospitals
Pharmacy
•852 Beds Gainesville
Dentistry
•696 Beds Jacksonville
Veterinary Medicine
Cancer Hospital
Public Health & Health
Children’s Hospital
Professions
Level I Trauma Centers
 5 Major Research Institutes
• UF Clinical & Translational Science Institute
• McKnight Brain Institute
• UF Genetics Institute
• Shands Cancer Center
• Institute on Aging
• Emerging Pathogens Institute
• Founded in 2008
• Provides over 40 services to UF&Shands researchers
– Phase I Clinical Trial Unit
– Clinical Research Center
– Core Laboratory Services
– Project ‘Navigators’ (consultant services)
• Provides various educational programs
– KL2 and TL1 awards
– Research Coordinator Certificate Program
– MD-PhD Training
– MSCI
 About the HSC Libraries
Health Science Center Library
(Gainesville)
11 Liaison Librarians
•7 Subject Specialists
•4 Functional and Subject Specialists)
– Consumer Health and
Community Engagement
– Distance Education
– Bioinformatics
– Clinical Research
Borland Library (Jacksonville)
•3 Librarians (Including Clinical
Librarian starting Mar 15, 2011)
Librarians hold full tenure-track faculty status;

5 new hires in 2010: doubling size of

Biomedical Health & Info Services Dept.
 The Clinical Research Librarian
• Library competed for funding
• UF Provost re-designated position for CTSI support
• Hired July 23, 2010
• Liaison to
– CTSI
– Emergency Medicine
– Pathology, Immunology & Laboratory Medicine
• Functions as cross-disciplinary expert in clinical
research
 Developing a New Role:
Challenges
• No ‘role models’
• Complexity of clinical research
• High learning curve
– Multiple Agencies and Regulations
– Unique to each institution
– New vocabulary (IRB, RAC, IND, DSR, RKRS…)
– Complex web of relationships to develop
 Developing a New Role:
Opportunities
• CTSI members involved in hiring committee
• UF highly invested in clinical & translational
research
• Other librarian-involved research collaborations in
development
• Library expanding clinical services & support for
EBP
• Previous 8 years experience in Emergency Medicine
facilitates new ED research collaborations at UF
 CTSI Integration
• Serve in CTSI Regulatory Knowledge & Research Support
(RKRS) Group
• Collaborate with RKRS members on studies/grants
• CTSI requested library instruction in academic course
• CTSI added literature searching services to RKRS portal
• Participation in CTSI Strategic Planning Retreat
• Representing UF on national CTSA Research Networking
Committee
• Representing UF on national REDLOC committee
 About the RKRS
CTSI Regulatory Knowledge & Research Support program

Develop a guided, single ‘pathway’ for clinical investigators to move from

‘idea’ to completed clinical study

Clinical Research Center REDCap Data Capture/Management

Institutional Review Board Quality Assurance

Research Administration & Research Subject Advocacy

Compliance Biostatistics

Dept. of Sponsored Research BioRepository

 Research Ethics Project
RKRS-facilitated Research Team
Focus: Conflict of Interest in UF College of Medicine
Team Members:
•UF COM’s Conflict of Interest Officer
•RKRS program director
•REDCap services director/biostatistician
•Health and Science Communications doctoral student
•CTSI research project manager
•Clinical Research Librarian
Manuscript in submission process
 Teaching
• Instructor in the CTSI’s credit-bearing
course “Introduction to Clinical and
Translational Research” (summer 2010,
2011)
• Taught literature searching skills to CTSI
MD-PhD students fall 2010
 Research Networking
• Representing UF on the CTSA’s national
Research Networking Committee
• Participating on the VIVO Outreach Team
at UF
 Beyond the CTSI
• Emergency Medicine
• Brain Cancer Patient/Caregiver Education
• NIH Public Access Policy Services
• Support for Systematic Reviews
• In-house Training for Librarians
 Emergency Medicine Research
• Joined research team of Dr. Latha Stead, ED Chief of
Clinical Research.
– Collaborating on systematic & structured reviews
• Providing training for ED research associates
• Providing mediated literature searches for ED faculty
• Serving as liaison librarian for Emergency Department
– Attending resident teaching conferences
– Providing training for residents & faculty
– Selecting library materials
– Developing LibGuide for Emergency Medicine e-resources
 Brain Tumor Patient Education
• Supporting library colleague on an
interdisciplinary study of the information
needs of brain tumor patients and their
caretakers
• Collaborative team led by Dr. Erin Dunbar
of the McKnight Brain Institute
 NIH Public Access Project
• Leading a team of librarians
• Developing library support services
– Creating materials including a LibGuide
– Creating prepared presentations
– Identifying UF departments not fully compliant
– Collecting information on Publisher’s PMC policies
– Investigating the value of providing ‘third-party
submission’ services
 Systematic Reviews
• Attended a 2.5 day workshop on writing
Systematic Reviews at U. Pittsburgh
• Training Colleagues
• Expanding library services to patrons
– Classes
– Consultations
– Collaborations
 Future Goals
• Increase support for investigators writing IRB protocols
• Develop relationship with IRB
• Develop further opportunities for clinical research
collaborations
• Train librarians in evidence-based practice
• Support and develop point-of-care clinical librarianship
services and leverage on these to increase involvement in
clinical research
 In Conclusion
• The role of a librarian (“informationist”)
specializing in clinical research is both innovative
and exciting.
• There are huge opportunities and significant
challenges ahead as we develop this new position
• This will serve as a role model for other libraries
supporting clinical and translational research in
the future