Ankylosing spondylitis or diffuse idiopathic skeletal hypero

stosis
(DISH) in Royal Egyptian mummies of 18th-20th Dynasties?
CT and
archaeology studies

Arthritis & Rheumatology 66.12 (2014): 3311-3316.

 INTRODUCTION

• 1297-1213 BC
Ramesses II
Merenptah (son)

X光:
• Ankylosing spondylitis
• diffuse idiopathic
skeletal hypertrophy
Can Assoc Radiol J. 2004;55:211–7.
Rheumatol Int. 2003; 23:1–5.
Harris, J. E., & Wente, E. F. (1980). An X-ray atlas of the royal mummies.
METHODS

• 1492–1153 BC
• 13 Egyptian mummies
• 18th Dynasty:
Amenhotep III
• 19th-20th Dynasties:
Ramesses II
Merenptah (son)

JAMA 2010; 303:638–47.

 King Amenhotep III (1390–1352 Flowing candle wax
BC)

RESULTS- King Amenhotep III

ALL 鈣化

Facet j. 沒融
合

肋脊椎關節
OA change disc 高度正常；骨刺； ALL 鈣
沒融合 化
King Ramesses II(1297-1213 BC): DISH ，非
AS
RESULTS- King Ramesses II

SI joint: 有骨刺；沒 fusion ；沒 ALL 鈣化；沒 fusion ； disc 正

DISCUSSION- 木乃伊化是否會影響判讀
• 木乃伊製作要用 :
natron 、 linen 、 resin
• 可能會沉積在
ant. longitudinal lig.

• 考古學診斷 DISH
1. 至少四節鈣化
2. extra-spinal nthesopathies
Ann Rheum Dis 1973; 32:354–63.
DISCUSSION- 法老們的症狀

• DISH:
Ramesses II and his son Merenptah
• ossified posterior longitudinal ligament
spinal and extraspinal ossifications

• Symptoms: Radiology 1976;119:559–68.

stiffness and pain
cervical DISH may cause dysphagia, airway
obstruction, and/or radicular complaints
LIMITATION
 CONCLUSIONS

• CT 排除了 ankylosing spondylitis 。

• 木乃伊的 CT findings 和現代人的 DISH 很相像。
• Ramesses II and his son Merenptah 顯示有 familial clustering
of DISH 。
• Mummification 所引起的變化，需要再多做研究。