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Replication Final New
Replication Final New
1.Primase.
2.DNA polymerase-
III holoenzyme.
3.DNA polymerase I.
4.Ribonuclease H.
5.DNA ligase.
Replication machinery
After the unwinding of DNA double
helix Primase enzyme synthesis
RNA primers as needed.
DNA Polymerase enzyme catalyze
the synthesis of DNA.
It has two limitations :
1. It needs primer for initiation.
2. It moves from 5’ to 3’.
DNA polymeraseIII Holoenzyme