Histology Presentation: Roll Numbers 30-35

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HISTOLOGY PRESENTATION

Roll Numbers 30-35


Classify organs and give two examples of
each
HOLLOW ORGANS SOLID ORGANS

• Stomach • Liver
• Urinary bladder • Kidneys
Enlist the epithelial modifications of the mucosa of
stomach
• Numerous longitudinal folds (gastric pits) –form rugae

CARDIAC FUNDUS PYLORUS

•Straight tubular •Straight tubular •Straight tubular


branched glands branched glands branced glands
•Ducts and glands •Ducts 1/3rd & glands •Ducts 2/3rd & glands
equal 2/3rd 1/3rd
•Gastric pits – 1/4th of •Gastric pits – 1/4th of •Gastric pits – ½ of
mucosa mucosa mucosa
Enlist different cell types lining the fundic gland in terms
of its location, shape and organelles
CELLS LOCATION SHAPE ORGANELLES
Mucous Lower part of Simple columnar Apical region – mucinogen granules
gastric pits - neck

Parietal Junction of Large cells, •Centrally locted rounded nucleus


gastric pit with rounded or •High density eosinophilic –
gastric glands - pyrimidal mitochondria
•Large golgi apparatus
isthmus •RER

Chief Lower region of Basophilic simple •Spherical basal nucleus


gastric glands columnar or •Secretory granules – pepsinogen &
pyrimidal gastric lipase

Stem Neck region Columnar cells - •Basally located nucleus


undifferentiated •Cell organelles – unremarkable
•Prominent ribosomes

Enteroendocrine Necks and bases Small irregular •Small membrane bound secretory
cells granules – GIT polypeptide
hormones (gastrin, secretin,
serotonin etc,)
Enlist the layers of stomach wall as hollow viscera
Give a brief account on surface modifications of mucosa &
submucosa in the small intestine in order to enhance absorption
Plicae Villi Microvilli Crypts of
circulares Leiberkuhn
•Valves of •Finger like •Apical surface •0.4 mm deep
Kerckering projections of •Increase surface invaginations of
•Permanent mucosa area by a factor of mucosa
feature •Increase surface 20 •Simple tubular
•Increase surface area ten fold glands
area by three •1 mm in length
times •10 to 40 per mm2
•Pronounced in •Duodenum-
jejunum leaflike
•Absent in •Jejunum-
proximal part of fingerlike
duodenum and •Ileum- club
distal half of shaped
ileum
Brunner’s Glands M-cells

Compound tubular glands Dome shaped epithelial modification


Present in duodenum of MALT (mucosal asscoiated
Absent in jejunum and ileum lymphoid tissue) – Peyer’s Patches
Antigen presenting cells
Present in ileum only
What do you understand by intestinal villi?
Explain its features depending on their location
Villi are permanent fingerlike projections of lamina propia
of the mucosa that extend into the intestinal lumen

Lacteals (lymph vessels)


Blood capillaries – numerous
Intestinal glands
Fibroblasts

Duodenum Jejunum Ileum


Leaf like Finger like Club shaped
THANKYOU

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