Labs

CBC, creatinine,
Algorithm based on Severity SGPT, SGOT
Markers
Confirmed COVID Positive Ferritin
LDH
Admitted as Inpatient
D-dimer
CRP
Assess severity of illness Troponin
Assess prognosis Procalcitonin
Do not routinely start antibiotics IL-6

Asymptomatic, Mild or Critical disease

Severe disease
Moderate disease

No specific COVID-19 therapy Refer to THERAPEUTIC MANAGEMENT

remdesivir 200 mg IV x 1, then 100 mg IV daily for 4 Refer to GUIDANCE FOR CRITICALLY ILL
days ICOVID PATIENTS
Supportive care
If on supplemental oxygen, dexamethasone 6 mg Follow daily LFTs and eGFR if on
Close monitoring, especially PO or IV daily for up to 10 days remdesivir
for those with multiple risk
factors for progression Supportive care, close monitoring especially for Dexamethasone strongly recommended
those with multiple risk factors for progression
Self-proning to improve Repeat labs at regular intervals
Decisions about alternative steroids, off- label
oxygenation status of non- immunomodulatory or other therapies can be
Self-proning to improve oxygenation status of
intubated hospitalized considered on a case- by-case
non-intubated hospitalized patients
patients
If on remdesivir, follow daily LFTs and eGFR
Adapted from Massachusetts General Hospital (MGH) COVID-19 Treatment Guidance
https://www.massgeneral.org/assets/MGH/pdf/news/coronavirus/mass-general-COVID-19-treatment-guidance.pdf
 Mild to
Moderate Supportive therapy.
COVID-19 Insufficient evidence to recommend for or against the use of any anti-viral agents.
Non- dexamethasone or other corticosteroids are NOT RECOMMENED.
Hospitalized

Hospitalized Supportive therapy.

but Does Not
dexamethasone or other corticosteroids are NOT RECOMMENED.
Require
Oxygen Insufficient evidence to recommend for or against the use of remdesivir. For patient at high risk of
Supplement disease progression, remdesivir may be appropriate.

Therapeutic Hospitalized
Requiring
Oxygen
remdesivir alone OR
dexamethasone plus remdesivir OR
Management Supplement dexamethasone alone

Hospitalized dexamethasone alone OR

Requiring O2
Supplement
dexamethasone plus remdesivir OR
via HFNC dexamethasone plus tocilizumab

Hospitalized dexamethasone OR
Requiring
O2 dexamethasone plus remdesivir OR
Supplement dexamethasone plus tocilizumab OR
via MV or
ECMO baricitinib plus remdesivir

Adapted from https://www.covid19treatmentguidelines.nih.gov/therapeutic-management/