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PEDIA Subgroup B
PEDIA Subgroup B
PEDIA Subgroup B
Diarrhea
HISTORY OF PRESENT ILLNESS
Apgar of 9,9
BS: 39 weeks
BW: 3000 grams.
Weight: 25kg
Height: 105cm
UAC: 11.5cm
DYSENTERY
Features Dysentery Acute diarrhea Persistent diarrhea
Bloody stool - - -
Varies/blood streaked
Color depends on blood - +
flow/location
Mucus +/- - -
Features Viral Gastroenteritis Appendicitis Acute Cholecystitis
Rovsing Sign - + -
Nausea + + +
Vomiting + + +
Abdominal
- +/- +
Distension
Admit to hospital:
● young infants (< 2 months old)severely ill children, who look
lethargic,have abdominal distension and tenderness or convulsion
● children with any another condition requiring hospital treatment.
Give an oral antibiotic (for 5 days) to which most local strains of Shigella are
sensitive.
● Give ciprofloxacin at 15 mg/kg twice a day for 3 days if antibiotic
sensitivityis unknown. If local antimicrobial sensitivity is known, follow
local guidelines.
● Give ceftriaxone IV or IM at 50–80 mg/kg per day for 3 days to severely
ill children or as second-line treatment.
● Give zinc supplements as for children with watery diarrhoea.
Follow-up
● Follow up children after 2 days, and look for signs of improvement, such
as no fever, fewer stools with less blood, improved appetite.
● Infants and young children
● Severely malnourished children
Supportive care
● Supportive care includes the prevention or correction of dehydration and
continued feeding. For guidelines on supportive care of severe acutely
malnourished children with bloody diarrhoea, see also Chapter 7 (p. 197).
● Never give drugs for symptomatic relief of abdominal or rectal pain or to
reduce the frequency of stools, as these drugs can increase the severity of
the illness.
● Treatment of dehydration
● Nutritional management
Complications:
● Dehydration
● Potassium depletion
● High fever
● Rectal prolapse
● Convulsions
● Haemolytic yremic syndrome
● Toxic megacolon
Enteroinvasive E.coli (EIEC)
● Infections present either with watery diarrhea or a dysentery syndrome
with blood, mucus, and leukocytes in the stools, as well as fever, systemic
toxicity, crampy abdominal pain, tenesmus, and urgency
● The illness resembles bacillary dysentery because EIEC shares virulence
genes with Shigella sp.
● Sequencing of multiple housekeeping genes inidcates that EEC is more
related to Shigella than to noninvase E.coli.
● EIEC diarrhea occurs mostly in outbreaks; however, endemic disease
occurs in developingh countries.
Treatment
● The cornerstone of management is appropriate fluid and electrolyte therapy. It
should be include oral replacement and maintenance with rehydration
solutions such as those specified by the WHO.
● Pedialyte and other readily available oral rehydration solutions are acceptable
alternatives. After refeeding, continued supplementation with oral rehydration
fluids is appropriate to prevent recurrence of dehydration. Early refeeding
(within 6-8 hr of initiating rehydration) with breast milk or infant formula or
solid foods should be encouraged.
Prevention of illness
● In the developing world, prevention of disease caused by pediatric
diarrheagenic E.coli is probably best done by maintaining prolonged
breastfeeding, paying careful attention to personal hygiene, and following
proper food and water handling procedures. Protective immunity against
diarrheagenic E.coli remains an active area of research, and no vaccines are
available for clinical use in children.