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Nursing: A Concept-Based Approach to

Learning
Volume One, Third Edition

Module 1
Acid–Base Balance

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Exemplar 1.C
Respiratory Acidosis

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Exemplar Learning Outcomes
Analyze metabolic acidosis as it relates to acid–base balance.

 Describe the pathophysiology of respiratory acidosis.

 Describe the etiology of respiratory acidosis.

 Compare the risk factors and prevention of respiratory acidosis.

 Identify the clinical manifestations of respiratory acidosis.

 Summarize diagnostic tests and therapies used by interprofessional teams in the


collaborative care of an individual with respiratory acidosis.

 Differentiate care of patients with respiratory acidosis across the lifespan.

 Apply the nursing process in providing culturally competent care to an individual with
respiratory acidosis.

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Overview
• Respiratory acidosis
– Caused by excess of carbonic acid
– Characterized by a pH <7.35
– PaCO2 >45 mmHg
– May be acute or chronic
– In chronic respiratory acidosis, bicarbonate is >26 mEq/L
– Kidneys compensate by retaining bicarbonate

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Pathophysiology and Etiology
• Both acute and chronic respiratory acidosis result from CO 2 retention
– Caused by alveolar hypoventilation

• Hypoxemia frequently accompanies respiratory acidosis

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Acute Respiratory Acidosis
• Results from sudden failure of ventilation
– Chest trauma
– Aspiration of foreign body
– Acute pneumonia
– Overdose of narcotics or sedatives

• PaCO2 rises rapidly

• pH falls markedly

• pH ≤7 can occur within minutes

• Hypercapnia

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Chronic Respiratory Acidosis
• Associated with chronic respiratory or neuromuscular conditions that affect alveolar
ventilation
• Majority have COPD → bronchitis, emphysema
• PaCO2 increases over time, remains high
• Kidneys retain bicarbonate
• pH often close to normal
• Acute hypercapnia may not develop when CO2 levels rise gradually
• Risk of carbon dioxide narcosis

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Risk Factors
• Acute lung disease

• Chronic lung disease

• Trauma

• Narcotic analgesics

• Airway obstruction

• Neuromuscular disease

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Clinical Manifestations (1 of 2)
• Acute respiratory acidosis
– PaCO2 levels rise rapidly
– Cause manifestations of hypercapnia
▪ Cerebral vasodilation
▪ LOC progressively decreases
– Rapid changes in ABGs
– Skin warm, flushed
– Pulse elevated

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Clinical Manifestations (2 of 2)
• Chronic respiratory acidosis
– Weakness
– Dull headache
– Sleep disturbances
– Impaired memory
– Personality changes

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Collaboration
• Care requires healthcare team
– Respiratory therapist
– Pharmacist
– Primary care provider
– Dietitian

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Diagnostic Tests (1 of 2)
• ABGs
– pH <7.35
– PaCO2 >45 mmHg
– Acute respiratory acidosis
▪ Bicarbonate level initially in normal range
▪ Increases to >26 mEq/L if condition persists
– Chronic respiratory acidosis
▪ PaCO2 may be significantly elevated
▪ HCO3 may be significantly elevated

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Diagnostic Tests (2 of 2)
• Serum electrolytes
– Chloride level <98 mEq/L

• Pulmonary function tests


– Determine whether chronic lung disease is cause of respiratory acidosis

• Other tests to identify underlying cause


– Chest x-ray
– Sputum studies
– Serum levels of suspected drugs

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Pharmacologic Therapy
• Bronchodilator drugs

• Antibiotics for respiratory infections

• Narcotic antagonists

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Respiratory Support
• Focus on improving alveolar ventilation, gas exchange

• Severe acidosis and hypoxemia


– Intubation and mechanical ventilation

• PaCO2 level lowered slowly

• O2 administered cautiously

• Pulmonary hygiene

• Adequate hydration

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Lifespan Considerations (1 of 3)
• Infants and children
– Risk factors
▪ Asthma
▪ Pneumonia
▪ Airway obstruction
▪ Acute pulmonary edema
▪ ARDS
▪ Head trauma
▪ Poisoning
– Critical ABG result is increased PaCO2

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Lifespan Considerations (2 of 3)
• Infants and children
– Clinical manifestations similar to those in adults
– Nursing management
▪ Assess mental, respiratory status
▪ Positioning
▪ Suctioning as needed
▪ Encouraging deep breathing

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Lifespan Considerations (3 of 3)
• Older adults
– Risk factors
▪ COPD
▪ Chest wall abnormalities
▪ Pneumonia
▪ Respiratory muscle weakness
– HCO3 retention by kidneys in compensation for CO2 retention from
hypoventilation
– Outcome depends on nature of illness, early diagnosis/treatment

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Patient Teaching: Instructions for Parents
• Children with asthma, airway obstruction, influenza, and pneumonia are at risk

• Teach parents prevention methods 


– Deep breathing (several times/day)
– Signs of infection
– Positioning to facilitate chest expansion
– Medication administration (as appropriate)
– Use of ordered devices (e.g., home respirators, nebulizers)

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Nursing Process
• Primary focus
– Improving breathing patterns
– Maintaining patent airway

• Teach patients how to make healthy lifestyle choices

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Assessment (1 of 2)
• Observation and patient interview
– Current manifestations
– Duration of symptoms
– Precipitating factors
– Chronic disease
– Current medications

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Assessment (2 of 2)
• Physical examination
– Mental status and LOC
– Vital signs
– Skin color and temperature
– Rate and depth of respirations
– Pulmonary excursion
– Lung sounds

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Diagnosis
• Possible nursing diagnoses include
– Airway Clearance, Ineffective
– Anxiety
– Breathing Pattern, Ineffective
– Cardiac Output, Decreased
– Gas Exchange, Impaired
(NANDA-I ©2014, 2015–2017)

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Planning
• Desired outcomes may include
– Adequate fluid intake
– Oxygenation saturation >90%
– Normal PaCO2 level
– pH balance

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Implementation (1 of 6)
• Nursing interventions include frequent assessment of
– Respiratory status
– Oxygen saturation levels
– LOC

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Implementation (2 of 6)
• Promote gas exchange
– Promptly evaluate and report ABG results
– Place in semi-Fowler or Fowler position as tolerated
– Administer O2 as ordered
– Monitor response to O2
– Immediately report increasing somnolence

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Implementation (3 of 6)
• Promote effective airway clearance
– Frequently auscultate breath sounds
– Encourage pursed-lip breathing
– Frequently reposition and encourage ambulation
– Encourage fluid intake
– Administer medications
– Provide percussion, vibration, postural drainage as ordered

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Implementation (4 of 6)
• Reduce anxiety levels
– Result of hypoxia and hypercapnia
– Remain with patient and monitor
– Explain procedures and treatments
– Reduce environmental stimuli
– Use calm, reassuring manner
– Allow supportive family members to remain with patient as much as possible

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Implementation (5 of 6)
• Reduce risk for injury
– Patients may experience blurred vision and altered LOC
– Assess LOC, mental status, orientation frequently
– Place call alarm controls within reach
– Manage rest, activity patterns
– Administer supplemental O2 as needed

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Implementation (6 of 6)
• Plan for discharge
– Teach patient and family about preventive measures and equipment
– Refer patient to substance abuse treatment if needed
– Encourage patient to receive immunizations
– Provide instructions when respiratory status is compromised
– Alert to early symptoms that warrant immediate attention

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Evaluation
• Expected outcomes may include
– Patient maintains patent airway
– Patient maintains appropriate breathing patterns to meet O 2 demands
– Patient remains conscious
– Patient does not display anxiety indicating potential hypoxia
– ABGs reflect pH and PaCO2 within acceptable range for patient

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