PEPTIDE FORMATIONN

Presented by
Engr. Esmael O. Larubis, MCHEM
Faculty, College of Arts and Sciences
Environmental Sustainability Officer-La Salle University
ChEngr License #0025299
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PEPTIDE FORMATION
PEPTIDES
 polymers made up alpha- amino
acid monomeric units (residues)
 linked by amide bonds (peptide
bonds) from the carboxylate group
of one residue and the amino
group of a second residue.

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PEPTIDE FORMATION
PEPTIDE FORMATION

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PEPTIDE FORMATION
PEPTIDE FORMATION

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PEPTIDE FORMATION
PEPTIDE FORMATION
Amino Acid Residue’s Name Amino Acid Residue’s Name
Alanine Alanyl Leucine Leucyl
Cystein Cysteinyl Methionine Methionyl
Aspartic Acid Aspartyl Asparagine Asparaginyl
Glutamic Acid Glutamyl Proline Prolyl
Phenylalanine Phenylalanyl Glutamine Glutaminyl
Glycine Glycyl Arginine Arginyl
Histidine Histidyl Serine Seryl
Isoleucine Isoleucyl Threonine Threonyl
Lysine Lysyl Valine Valyl
Tryptophan Tryptophanyl
Tyrosine Tyrosyl

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PEPTIDE FORMATION
PEPTIDE FORMATION

Ser-Gly-Tyr-Ala-Leu or SGYAL
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PEPTIDE FORMATION
PEPTIDE FORMATION
1. Water (H2O) is lost
2. Amide bond (peptide bond- CONH) is formed
3. Peptide is produced
Two amino acids = dipeptide
Three amino acids = tripeptide
Four amino acids = tetrapeptide
Five amino acids = pentapeptide

2- 10 amino acids = oligopeptides

4. Name the peptide from the amino end to

carboxyl end
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 PEPTIDE FORMATION
PEPTIDE FORMATION
Given the following structural formula of the peptide:
a. Classify the type of peptide;
b. Is it an Oligopeptide?
c. How many peptide bonds are there?
d. What is the name of the peptide?

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 PEPTIDE FORMATION
PEPTIDE FORMATION
Given the following structural formula of the peptide:
a. Classify the type of peptide; (tetrapeptide)
b. Is it an Oligopeptide? (Yes, because it has less than or equal to 10 amino acids)
c. How many peptide bonds are there? (four)
d. What is the name of the peptide?(valylphenylalanyltyrosyllysine)

- END-
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