Immunology

Acute vs Chronic
Inflammation
Acute vs Chronic Inflammation
• Acute Inflammation:
Short term process
occurring in response to
tissue injury
• Appear in minutes to
hours
• Purely physical damage
• Activation of immune
system
• Three main processes
involved in acute
inflammation
Acute vs Chronic Inflammation
1) Increased blood flow
2) Increased permeability
3) Migration of Leucocytes
• Increased blood flow
• Dilatation of blood
vessels in the effected
region
• Redness of the effected
area
• Increased in
temperature of effected
area
 Acute vs Chronic Inflammation
• Increased Permeability
• Permeability causes the
leakage of plasma into
tissue interstetium
• Accumulation of fluid in
tissue
• Edema: swelling of the
effected area due to
https://courses.washington.edu/conj/
inflammation/acuteinflam.htm
additional accumulation
of fluid into interstitial
space of the region
• Endothelial cells
separate
 Acute vs Chronic Inflammation
• Migration of Leucocytes
• Chemotaxsis: increased
movement of Leucocytes
towards the site of
infection
• Accumulation of fluid in
tissue

https://courses.washington.edu/conj/
inflammation/acuteinflam.htm
Immunology

Adverse Effects of
Inflammation
Adverse Effects of Inflammation
• Inflammation is
associated with general
flu like symptoms
including
• Fever
• Chills
• Fatigue/Lethargy/Loss of
energy
• Headaches
• Loss of appetite
• Body pains
• Muscle stiffness