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Dehydration

Screening and blood testing for dehydration

Blood work
1. Biochemistry urinalysis
a. electrolyte disturbances (Na+, K+, Cl-, HCO3-, 2. ↑ osmolality
Ca++) 3. Dark color
b. acid base panel (pCO2, pO2, BE, pH, ↑BUN) 4. ↑ urine specific gravity
c. ↑ glucose (in DM)
d. ↑ osmolality Others
5. Skin turgor
2. Complete blood count
6. Hypotension
a. ↑ hematocrit
7. Stool culture (C.difficile toxin, ONP)
b. ↑ albumin
8. Cortisol and Aldosterone (Addison disease)
9. ADH levels
Physiology of normal water intake in
pediatrics
• Children are more resistant to water-balance variations than adults.
• Water is constantly being lost, therefore it is crucial to have proper intake amounts

• Methods for calculating daily maintenance fluid volume


1. Body weight method (maximum 2.4L\day)
a. 0-10kg: 100ml\kg\day
b. 11-20kg: 1,000ml+50ml\kg\day
c. >20kg: 1,500ml + 20ml\kg\day

2. Hourly maintenance water rate


a. 0-10kg: 4ml\kg\h
b. 10-20kg: 40ml\h + 2ml\kg\hr X (weight -10kg)
c. >20kg: 60ml\h + 1ml\kg\hr X (weight -20kg)
Water-loss physiology in pediatrics

• Children are more prone to water loss


a. Lower water storage
b. Increased surface-area: body-mass
c. Underdeveloped thirst sensors
d. Dependence on care-givers

• Sources of water loss


a. Through urine (60%)
b. Through insensible-losses (35%, skin and lungs)
c. Through stool (5%)
Etiology of dehydration
8. Substances (e.g. alcohol or
medication)
1. Vigorous exercise
a. diuretics
2. Not drinking enough
b. alpha-blockers (Cardura)
3. Vomiting
c. anti-depressants
4. Diarrhea
d. laxatives
5. excessive sweating
e. chemotherapy
6. Inability sweating
f. anti-histamines
7. Inability to swallow
g. ectasy
Treatment

• According to etiology of dehydration

1. Light dehydration:
-Standard home solutions (salted rice water, salted yogurt )
- Oral water-replacement

2. Medium dehydration (with paused vomiting)


- Give water orally in a slower pace (5-10 minutes interval)
- might consider IV-solution
( normal-saline + 30mEq\L-Sodium-bicarbonate + 20mEq\L-KCL ) for every ml loss every 1-6h

3. Severe dehydration
- Provide fluids according to urine output (similar formula as medium dehydration)
Bibliography

1. Kliegman, Stanton, St Geme, Schor. Nelson- Textbook of


Pediatrics, 20th edition, Elsevior, 2016

2. Rehydration project- http://rehydrate.org/

3. The National academies of sciences engineering medicine-


Dietary reference intakes- 2004
4. John E. Elleshaw, Jane M Sutcliffe, Cicely M, saunders.
Dehydration and the dying patient, St. Chrisopher’s Hospice,
London, England, 1995
THANK YOU!

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