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Protocol For Clinical Referral
Protocol For Clinical Referral
30
25
Deaths (millions)
20
15
10
0
2004 2015 2030 2004 2015 2030 2004 2015 2030
High income Middle income Low income
Noncommunicable Diseases
Adult Overweight and Obesity in Arab Countries
High income Cardiovascular diseases
Cancers
Other noncommunicable diseases
Western Pacific
Injuries
HIVAIDS
Americas
Other infectious and parasitic diseases
Maternal and nutritional conditions
Eastern Mediterranean
Europe
Africa
0 2 4 6 8 10 12
Death rate per 1000 adults aged 15–59 years
Noncommunicable Diseases
Burden of disease in disability adjusted life years
Facts about NCD in China
Communicable, ma-
ternal, neonatial,
and nutritional dis-
orders; 列 1; 49; 6%
Injuries; 列
1; 80; 10%
Other NCDs;
CVD; 列 1;
列 1; 73; 9% 313; 38%
Chronic
Respiratory In total, NCDs accounted for
Diseases; Cancer; 列 1;
213; 26% 70.1 million deaths (85%),
列 1; 102;
12% 18.7% up from 1990*
• NCDs threaten progress towards the UN Millennium Development Goals and post-2015
development agenda. Poverty is closely linked with NCDs. The rapid rise in NCDs is
predicted to impede poverty reduction initiatives in low-income countries, particularly
by increasing household costs associated with health care. Vulnerable and socially
disadvantaged people get sicker and die sooner than people of higher social positions,
especially because they are at greater risk of being exposed to harmful products, such
as tobacco or unhealthy food, and have limited access to health services.
• In low-resource settings, health-care costs for cardiovascular diseases, cancers, diabetes
or chronic lung diseases can quickly drain household resources, driving families into
poverty. The exorbitant costs of NCDs, including often lengthy and expensive treatment
and loss of breadwinners, are forcing millions of people into poverty annually, stifling
development.
• In many countries, harmful drinking and unhealthy diet and lifestyles occur both in
higher and lower income groups. However, high-income groups can access services and
products that protect them from the greatest risks while lower-income groups can often
not afford such products and services.
Prevention and control of NCDs
• Primary prevention
A comprehensive approach is needed that requires all
sectors, including health, finance, foreign affairs,
education, agriculture, planning and others, to work
together to reduce the risks associated with NCDs, as
well as promote the interventions to prevent and
control them.
An important way to reduce NCDs is to focus on
lessening the risk factors associated with these
diseases.
Structured Primary Health-care Approach
• Through a primary health-care approach to strengthen early
detection and timely treatment. These measures can be
implemented in various resource levels. The greatest impact can
be achieved by creating healthy public policies that promote NCD
prevention and control and reorienting health systems to address
the needs of people with such diseases.
• Lower-income countries generally have lower capacity for the
prevention and control of noncommunicable diseases.
• High-income countries are nearly 4 times more likely to have NCD
services covered by health insurance than low-income countries.
Countries with inadequate health insurance coverage are unlikely
to provide universal access to essential NCD interventions.
WHO response
• Under the leadership of the WHO more than 190 countries agreed in 2011 on global
mechanisms to reduce the avoidable NCD burden including a Global action plan for the
prevention and control of NCDs 2013-2020. This plan aims to reduce the number of
premature deaths from NCDs by 25% by 2025 through nine voluntary global targets. The nine
targets focus in part by addressing factors such as tobacco use, harmful use of alcohol,
unhealthy diet and physical inactivity that increase people's risk of developing these diseases.
• The plan offers a menu of “best buy” or cost-effective, high-impact interventions for meeting
the nine voluntary global targets such as banning all forms of tobacco and alcohol advertising,
replacing trans fats with polyunsaturated fats, promoting and protecting breastfeeding, and
preventing cervical cancer through screening.
• In 2015, countries will begin to set national targets and measure progress on the 2010
baselines reported in the Global status report on noncommunicable diseases 2014. The UN
General Assembly will convene a third high-level meeting on NCDs in 2018 to take stock of
national progress in attaining the voluntary global targets by 2025.
Cardiovascular diseases
• Cardiovascular disease is caused by disorders of the heart
and blood vessels, and includes coronary heart disease
(heart attacks), cerebrovascular disease (stroke), raised
blood pressure (hypertension), peripheral artery disease,
rheumatic heart disease, congenital heart disease and heart
failure.
• Although heart attacks and strokes are major killers in all
parts of the world, 80% of premature deaths from these
causes could be avoided by controlling the main risk factors:
tobacco, unhealthy diet and physical inactivity.
29
Cardiovascular diseases:
Facts and figures
30
Cardiovascular diseases:
Contributing factors
31
Cardiovascular diseases:
Prevention
32
Cardiovascular diseases:
Prevention
It has been predicted that mortality from coronary heart disease (CHD) in
the United Kingdom could be halved by small changes in cardiovascular risk
factors: a 1% decrease in cholesterol in the population could lead to a 2–4%
CHD mortality reduction; a 1% reduction in smoking prevalence could lead
to 2000 fewer CHD deaths per year; and a 1% reduction in population
diastolic blood pressure could prevent around 1500 CHD deaths each year.
80% of the reduction in CHD mortality in Finland during the period of 1972–
1992 has been explained by a decline in the major risk factors. Similarly, in
Ireland, almost half (48.1%) of the reduction in CHD mortality rates during
1985–2000 among those aged 25–84 years has been attributed to favorable
trends in population risk factors. In both countries, the greatest benefits
appear to have come from reductions in mean cholesterol concentrations,
smoking prevalence and blood pressure levels.
33
Cardiovascular diseases:
Treatment
• Effective measures are available for people at
high risk. For example, combination drug
therapy (such as aspirin, beta blocker, diuretic
and statin) can lead to a 75% reduction in
myocardial infarction (heart attack) among those
at high risk of having one.
• But many such interventions are not being
implemented, and about half of coronary
patients in the world still require more intensive
blood pressure management.
34
Tobacco
Rising production and consumption in developing
countries
Smoking prevalence in Bangladesh (1995)
Clinical work-up/CVS
Cancer
• Cancer is the uncontrolled growth and
spread of cells that arises from a change in
one single cell. The change may be started
by external agents and inherited genetic
factors and can affect almost any part of the
body. The transformation from a normal cell
into a tumour cell is a multistage process
where growths often invade surrounding
tissue and can metastasize to distant sites.
38
Cancer: Interaction between a person’s genetic
factors and any of three categories of external
agents
39
Cancer:
the majority of cancer deaths
40
Cancer:
risk factors for cancer
• tobacco use
• unhealthy diet
• insufficient physical activity
• the harmful use of alcohol
• Infections (hepatitis B, hepatitis C (liver cancer), human
papillomavirus (HPV; cervical cancer), Helicobacter pylori
(stomach cancer)
• Radiation
• variety of environmental and occupational exposures of
varying importance
41
Cancer:
policy
42
Cancer:
policy
43
Cancer:
national cancer control programme
44
Chronic respiratory diseases:
Quick facts and figures
• 71% of all lung cancer deaths
• 42% of chronic respiratory disease worldwide.
• Of the six WHO regions, the highest overall prevalence for
smoking in 2008 was estimated to be the in the European
Region, at nearly 29%.
45
Chronic respiratory diseases:
Quick facts and figures
• Survey data from 2002–2007 indicate that over half of all
children aged 13–15 years in many countries in the European
Region are exposed to second-hand tobacco smoke at home.
Second-hand smoke causes severe respiratory health
problems in children, such as asthma and reduced lung
function; and asthma is now the most common chronic
disease among children throughout the Region.
46
Chronic respiratory diseases:
Quick facts and figures
• According to the latest available data for 1997–2006, over
12% of infant deaths in the world are due to respiratory
diseases.
• Indoor air pollution from biological agents related to damp
and mould increases the risk of respiratory disease in
children and adults. Children are particularly susceptible to
the health effects of damp, which include respiratory
disorders such as irritation of the respiratory tract, allergies
and exacerbation of asthma. Damp is often associated with
poor housing and social conditions, poor indoor air quality
and inadequate housing hygiene.
47
Chronic respiratory diseases:
Quick facts and figures
• Increasing evidence suggests that allergic sensitization,
which is the most common precursor to the development of
asthma, can already occur antenatally. Emphasis on the
health, nutrition and environment of the pregnant woman
and the unborn child are therefore essential.
• Ozone pollution causes breathing difficulties, triggers
asthma symptoms, causes lung and heart diseases, and is
associated with about 21 000 premature deaths per year in
25 countries in the WHO European Region.
48
Chronic respiratory diseases:
Quick facts and figures
• Most countries in the world and the European Region have
introduced a wide range of comprehensive policies to reduce
and eliminate tobacco smoke. For example, the advertising
of cigarettes and the sale of tobacco products to minors have
been banned in more than 80% of the countries in the
Region. Smoking in restaurants and bars continues to be
regulated less strictly, however. Ireland, Turkey and the
United Kingdom are the first countries to make public places
100% smoke free.
49
Diabetes
• There is an emerging
global epidemic of
diabetes that can be traced
back to rapid increases in
overweight, obesity and
physical inactivity.
51
Diabetes: Quick facts and figures
• Diabetes is predicted
to become the
seventh leading cause
of death in the world
by the year 2030.
52
Diabetes: Quick facts and figures
• 80% of diabetes
deaths occur in
low- and middle-
income countries.
• In developed countries
most people with
diabetes are above the
age of retirement,
whereas in developing
countries those most
frequently affected are
aged between 35 and 64.
53
Diabetes: Health implications
54
Diabetes: Prevention
Without urgent action, diabetes-related deaths will increase
by more than 50% in the next 10 years. To help prevent type
2 diabetes and its complications, people should:
• Achieve and maintain healthy body weight.
• Be physically active - at least 30 minutes of regular,
moderate-intensity activity on most days.
• Early diagnosis can be accomplished through relatively
inexpensive blood testing.
• Treatment of diabetes involves lowering blood sugar and the
levels of other known risk factors that damage blood vessels.
• Tobacco cessation is also important to avoid complications.
55
Diabetes: Control
• People with type 1 diabetes require insulin; people with type
2 diabetes can be treated with oral medication, but may also
require insulin.
• Blood pressure control
• Foot care
Other cost saving interventions include:
• Screening and treatment for retinopathy (which causes
blindness);
• Blood lipid control (to regulate cholesterol levels);
• Screening for early signs of diabetes-related kidney disease
and treatment.
These measures should be supported by a healthy diet,
regular physical activity, maintaining a normal body weight
and avoiding tobacco use.
56
Obesity
• Obesity is one of the greatest public health challenges of the
21st century. Its prevalence has tripled in many countries of
the WHO European Region since the 1980s, and the numbers
of those affected continue to rise at an alarming rate,
particularly among children.
• In addition to causing various physical disabilities and
psychological problems, excess weight drastically increases a
person’s risk of developing a number of noncommunicable
diseases (NCDs), including cardiovascular disease, cancer
and diabetes.
• The risk of developing more than one of these diseases (co-
morbidity) also increases with increasing body weight.
57
Obesity
Overweight and obesity
are defined as "abnormal
or excessive fat
accumulation that may
impair health“
58
Obesity: Quick facts and figures
More than 1.4 billion adults
were overweight in 2008,
and more than half a billion
obese
59
Obesity: Quick facts and figures
Globally, over 40 million
preschool children were
overweight in 2008
60
Obesity: Quick facts and figures
Overweight and obesity are linked
to more deaths worldwide than
underweight
61
Obesity: Quick facts and figures
Supportive environments and
communities are fundamental in
shaping people’s choices and
preventing obesity
63
Noncommunicable diseases:
Current status and trends in risk factors
The prevalence of these risk factors varied between country
income groups, with the pattern of variation differing between risk
factors and with gender. High-, middle- and low-income countries
had differing risk profiles.
Several risk factors have the highest prevalence in high-income
countries. These include:
1. physical inactivity among women,
2. total fat consumption,
3. raised total cholesterol.
Some risk factors have become more common in middle-income
countries. These include:
1. tobacco use among men,
2. overweight and obesity.
64
Noncommunicable diseases:
parameters for estimation of behavioural and
metabolic risk factors
• current daily tobacco smoking: the percentage of the
population aged 15 or older who smoke tobacco on a daily
basis.
• physical inactivity: the percentage of the population aged 15
or older engaging in less than 30 minutes of moderate
activity per week or less than 20 minutes of vigorous activity
three times per week, or the equivalent.
• raised blood pressure: the percentage of the population
aged 25 or older having systolic blood pressure ≥ 140 mmHg
and/or diastolic blood pressure ≥90 mmHg or on medication
to lower blood pressure.
65
Noncommunicable diseases:
parameters for estimation of behavioural and metabolic risk factors
67
Noncommunicable diseases:
Prevention and Control of Noncommunicable
Diseases
• There is the 2008-2013 Action Plan for the
implementation of the WHO Global Strategy on the
Prevention and Control of Noncommunicable Diseases.
This Action Plan was endorsed by the 2008 World Health
Assembly.
• It provides countries a roadmap for taking action against
NCDs, including raising the priority of NCD control,
improving disease surveillance, enabling governments to
take comprehensive action against the diseases, and
protecting countries, particularly developing, from the
burden of the epidemic.
68
Noncommunicable diseases:
The six objectives of the 2008-2013 Action Plan are:
• To raise the priority accorded to noncommunicable
disease in development work at global and national
levels, and to integrate prevention and control of such
diseases into policies across all government departments
• To establish and strengthen national policies and plans
for the revention and control of noncommunicable
diseases
• To promote interventions to reduce the main shared
modifiable risk factors for noncommunicable diseases :
tobacco use, unhealthy diets, physical inactivity and
harmful use of alcohol
69
Noncommunicable diseases:
The six objectives of the 2008-2013 Action Plan are:
70
Clinical Work-up
• Motivational Interviewing.
• “We know what works, we know what it costs
and we know that all countries are at risk. We
have an Action Plan to avert millions of
premature deaths and help promote a better
quality of life for millions more.”
Referrals And Referring
Protocols
• Develop or strengthen, where applicable,
preventive, promotive and curative
programmes to address noncommunicable
diseases and conditions, such as
cardiovascular diseases, cancer, diabetes,
chronic respiratory diseases, injuries, violence
and mental health disorders and associated
risk factors, including alcohol, tobacco,
unhealthy diets and lack of physical activity.
• The economic impact of this increase will be substantial because working-age adults
account for a high proportion of the NCD burden. Effective approaches to reduce the NCD
burden in LMIC include a mixture of population-wide and individual interventions. Such
cost-effective interventions are already available and include methods for early detection
of NCDs and their diagnoses using inexpensive technologies, non pharmacological and
pharmacological approaches for modi"cation of NCD risk factors and affordable
medications for prevention and treatment of heart attacks and strokes, diabetes, cancer
and asthma. These low technology interventions, if effectively delivered, can reap future
savings in terms of reduced medical costs, improved quality of life and productivity.
However, due to weak health systems, there are substantive gaps in their implementation
particularly in LMIC. Ef"cient use of limited health care resources, sustainable health
"nancing mechanisms, access to basic diagnostics and essential medicines and organized
medical information and referral systems are imperative for provision of equitable care for
people with and at risk of NCDs. They require long-term care that is proactive, patient
centered, community based and sustainable. Such care can be delivered equitably only
through health systems based on primary health care (PHC).