Professional Documents
Culture Documents
Digestive Sys
Digestive Sys
Contents:
Digestion Treatment of Ulcer
Mechanism of Action of PPI
GI System Parts short Description
Ulcer
Types of Ulcer
What is Peptic Ulcer?
GERD
Zollinger Ellison syndrome
Erosive Esophagitis
H. Pylori
Digestion:
Phases of Digestion
Ingestion
Peristalsis
Digestion
Absorption
The Digestive System
COMPONENTS:
Mouth
Esophagus
Stomach. ACCESSORY DIGESTIVE ORGANS
Small Intestine Teeth
Tongue
Large Intestine
Gallbladder
Salivary Glands
Liver
Pancreas
Enzymes
Causes
A bacterium called H.pylori
Excessive use of NSAIDs
Smoking
Caffeine
GASTRO-OESOPHAGEAL
(GORD) OR GASTRO
ESOPHAGEAL REFLUX
DISEASE (GERD)
Gastric reflux disease, or acid reflux
disease
Chronic symptom of mucosal damage.
Caused by stomach acid coming up from
the stomach into the esophagus.
GERD is usually caused by abnormal
relaxation of the lower esophageal
sphincter.
GORD SYMPTOMS
Heartburn
Regurgitation (reflux of mixture of gastric juices & undigested
food)
Difficulty in swallowing (dysphagia)
Increased salivation (also known as water brash)
NERD (NON EROSIVE REFLUX DISEASE)
SYMPTOMS OF ESOPHAGITIS
Difficulty when swallowing
Pain when swallowing
Acid reflux (heartburn)
Bleeding, either as blood in vomit or in stools (turning stools black)
REFLUX ESOPHAGITIS
Omeprazole
Lansoprazole
Esomeprazole
Pantoprazole
PPIs block secretion of hydrogen ions into the stomach.
Rabeprazole
Dexlansoprazole
PROTON PUMP
Proton pumps are a special kind of transporter that push hydrogen ions from areas
of low concentration to areas with high concentration.
Occur in Parietal cells.
Involved in production of gastric acid
MODE OF ACTION OF PPI