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HTA Eng Noua
HTA Eng Noua
HTA Eng Noua
Stroke
Cardiac volume
output
Heart rate
Blood
pressure vascular
Peripherial structure
resistance Endothelial
factors
Stroke volume (L/min)
depends on
intravascular volum
myocardial contraction
preload
afterload
contractility
Miocardial contraction
Absorption ↑ Na⁺
Aldosteron ↑ ↑ Peripherial resistance
↑ Intravascular volume
↑ Cardiac output
↑ Blood pressure
Etiopathogenesis of essential hypertension
The additional action of environmental factors
• obesity - is a major cause in essential hypertension. The mechanisms
involved are: increased activity of the SNS, activation of the RAAS,
compression of the kidneys with the fat accumulated around them.
• sedentary lifestyle - hypodynamics leads to obesity
• alcohol consumption in high doses - 50% of alcohol addicts have
high blood pressure
• increased salt intake - leads to fluid retention and volume expansion
• stress - in response to stress there is excessive sympathetic
stimulation
• smoking - tobacco increases the release of norepinephrine, which
contributes to increased BP, stimulates atherosclerosis
• familiar eating habits - increased intake of carbohydrates, saturated
fats
Diagnostic plan:
1. Symptoms
2. History of disease
3. Physical examination
4. Repeated measurements of BP values
5. Paraclinical investigations
Symptoms collection
in office
• by the medical staff
out-of-office
• by the patient at home - HBPM
• automatic -ABPM (Holter) for
a period of 24/h
Office BP and out-of-office BP have an independent
Three BP measurements should be recorded, 1–2 min apart, and additional measurements only if the first two
readings differ by >10 mmHg. BP is recorded as the average of the last two BP readings.
Additional measurements may have to be performed in patients with unstable BP values due to arrhythmias, such
as in patents with AF, in whom manual auscultatory methods should be used as most automated devices have not
been validated for BP measurement in patients with AF.
Use a standard bladder cuff (12–13 cm wide and 35 cm long) for most patients, but have larger and smaller cuffs
available for larger (arm circumference >32 cm) and thinner arms, respectively.
The cuff should be positioned at the level of the heart, with the back and arm supported to avoid muscle
contraction and isometric exercise-dependant increases in BP.
When using auscultatory methods, use phase I and V (sudden reduction/disappearance) Korotkoff sounds to
identify SBP and DBP, respectively.
Measure BP in both arms at the first visit to detect possible between-arm differences. Use the arm with the higher
value as the reference.
Measure BP 1 min and 3 min after standing from a seated position in all patients at the first measurement to
exclude orthostatic hypotension. Lying and standing BP measurements should also be considered in subsequent
visits in older people, people with diabetes, and people with other conditions in which orthostatic hypotension
may frequently occur.
• the prevalence varies between studies, can account for up to 30 − 40% of people
(and >50% in the very old).
• Pulse pressure (in older people) ≥60 mmHg. Carotid–femoral PWV >10 m/s
ECG LVH (Sokolow–Lyon index >35 mm, or R in aVL ≥11 mm; Cornell voltage duration
Echocardiographic LVH [LV mass index: men >50 g/m2; women >47 g/m2. (height in
indexation for BSA (body surface area); may be used in normal-weight patients; LV
3.4–34 mg/mmol) (preferentially on morning spot urine) Moderate CKD with eGFR >30–59
>2440 mm.ms
ECG left ventricular hypertrophy
Transthoracic echocardiography in hypertension
12-lead ECG
Asssessment of HMOD
Lifestyle interventions for patients with HTA
Blood pressure treatment
Treatment for uncomplicated hypertension